NCT02510287

A Comparison of Epidural Analgesia: Continuous Infusion Versus Programmed Intermittent Boluses

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 128 (actual)
• Sponsor: Fundación Santa Fe de Bogota · Academic / Other
• Sex: Female
• Age: 18 Years – 45 Years
• Healthy volunteers: Accepted

Summary

The analgesic approach in labor can be done in different ways, among which the neuraxial approach has shown the best analgesic results and fetal outcomes. Currently, programmed epidural intermittent bolus has been included in the neuraxial approach for a better distribution of the solution into the epidural space as compared with the continuous infusion strategy. In this study, the investigators seek to compare both strategies in 132 laboring women.

Conditions

• Labor Pain

Interventions

Type	Name	Description
DRUG	Bupivacaine and Fentanyl Initial Dose	10 ml of 0.1% bupivacaine (2 ml of 0.5% bupivacaine and 50 mcg / ml fentanyl in 7 ml of normal saline solution)
DRUG	Bupivacaine and Fentanyl: Continuous Epidural Infusion	0.1% bupivacaine and fentanyl 2 mcg / ml (8-12 ml / hour)
DRUG	Bupivacaine and Fentanyl: Programmed Intermittent Epidural Bolus	A 0.1% bupivacaine and fentanyl 2 mcg / ml (8-12ml) bolus will be administered each hour at a rate of 500ml/hour
DRUG	Rescue Bolus	Upon patient request, rescue bolus of 8-10 ml of 0.1% bupivacaine will be administered.
DRUG	Lidocaine	If needed, during the second phase (9-10 centimeters of cervical dilation) a 2% lidocaine without epinephrine (8-10 cc) bolus will be administered.

Timeline

• Start date: 2015-07-01
• Primary completion: 2016-05-01
• Completion: 2016-05-01
• First posted: 2015-07-29
• Last updated: 2016-05-20

Locations

1 site across 1 country: Colombia