NCT02122705

A Case Series of VPIA Using Remifentanil for Labour and Delivery

A Case Series of Vital Signs-controlled, Patient Assisted Intravenous Analgesia (VPIA) Using Remifentanil for Labour and Delivery

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 29 (actual)
• Sponsor: KK Women's and Children's Hospital · Other Government
• Sex: Female
• Age: 18 Years – 45 Years
• Healthy volunteers: Not accepted

Summary

This study is a prospective case series aiming to evaluate a new VPIA remifentanil algorithm which would benefit labouring mothers who are unable or unwilling to receive epidural analgesia.

Detailed description

This study proposes a novel Vital signs-controlled, patient-assisted intravenous analgesia (VPIA) regimen that will enhance the efficacy, safety and personalization of remifentanil therapy for labouring women. This system will study the parturient's pattern of analgesic use in 15 min epochs and titrate the demand doses and basal infusion rate to maintain a plasma level of remifentanil that is appropriate for the degree of pain felt. The system incorporates vital signs (pulse oximetry and heart rate values) into the algorithm which would temporarily stop the pumps and step down doses accordingly when predefined critical values are reached.

Conditions

• Labor Pain

Interventions

Type	Name	Description
DEVICE	VPIA remifentanil	Vital signs controlled patient assisted intravenous analgesia using remifentanil

Timeline

• Start date: 2012-05-01
• Primary completion: 2016-01-01
• Completion: 2016-06-01
• First posted: 2014-04-24
• Last updated: 2017-02-07

Locations

1 site across 1 country: Singapore