NCT01016821

Oxycodone for Labor Pain - Pharmacokinetics (PK), Safety and Efficacy

The Efficacy and Safety of Intravenous Oxycodone and Plasma Oxycodone Concentrations in Labour Pain

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 15 (estimated)
• Sponsor: Kuopio University Hospital · Academic / Other
• Sex: Female
• Age: 18 Years – 45 Years
• Healthy volunteers: Not accepted

Summary

Childbirth is one of the most painful events that a woman is likely to experience, and thus is a major concern for most parturient. Severe pain releases stress mediators and may thus compromise fetus well-being if placental perfusion is decreased. Epidural analgesia is the golden standard for the management of severe labor pain. However, it could not always be used both due the parturient related factors and the organizational reasons.However, the knowledge on safety and efficacy of oxycodone involving mother, fetus and newborn is limited. Aim of the study is firstly, to evaluate the efficacy and safety of oxycodone in labor pain healthy parturients. Secondly, to measure parturient's blood oxycodone concentration during labour and fetal concentration from placental umbilical vein and artery right after birth.

Conditions

• Labor Pain

Interventions

Type	Name	Description
DRUG	Oxycodone	Intravenous, 1 mg, 5 times, in every 5 minutes, duration of drug administration 25 minutes

Timeline

• Start date: 2009-11-01
• Primary completion: 2010-12-01
• Completion: 2010-12-01
• First posted: 2009-11-20
• Last updated: 2011-01-11

Locations

1 site across 1 country: Finland