NCT03882814

Pethidine Analgesia on Labor Duration

The Effect of Pethidine Analgesia on Labor Duration and Maternal-Fetal Outcomes

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 240 (actual)
• Sponsor: Kanuni Sultan Suleyman Training and Research Hospital · Academic / Other
• Sex: Female
• Age: 18 Years – 40 Years
• Healthy volunteers: Not accepted

Summary

Although opioid analgesics are used to treat labor pain, there are still concerns about their side effects. The researchers in this study; aimed to evaluate the effect of pethidine on active phase duration of labor, labor pain and maternal-neonatal. 50 mg pethidine will be administered intramuscularly to the cases to be included in the study group. The patients in the control group will be given placebo injections. Vital signs of all cases included in the study will be checked at 0, 5, 15, 30, 45 and 60 minutes. Pain will also be assessed by Visual Analogue Scale (VAS) before injection and at the 1st and 2nd hour after injection. Delivery times, maternal side effects, neonatal apgar scores and fetal findings will be recorded.

Conditions

• Labor Pain

Interventions

Type	Name	Description
DRUG	pethidine	Pethidine 50 mg intramuscular (IM) injection was performed when cervical dilatation was at or greater than 4 cm and the cardiotocogram uterine contraction recordings of 200 Montevideo units was reached. Opioid analgesia (pethidine HCl - 50 mg I.M.) was given following amniotomy.
DRUG	Placebo - Concentrate	Intramuscular saline was administered to the control group as placebo. Salin intramuscular (IM) injection was performed when cervical dilatation was at or greater than 4 cm and the cardiotocogram uterine contraction recordings of 200 Montevideo units was reached. salon was given following amniotomy.

Timeline

• Start date: 2017-07-01
• Primary completion: 2018-06-01
• Completion: 2018-06-01
• First posted: 2019-03-20
• Last updated: 2020-10-22

Locations

1 site across 1 country: Turkey (Türkiye)