| Recruiting | Machine Learning in Guiding rTMS Treatment for GWI-Related Headaches and Body Pain NCT07325513 | Veterans Medical Research Foundation | N/A |
| Recruiting | Treatment Response in Patients With Medication-Overuse Headache NCT07487649 | Sultan 1. Murat State Hospital | — |
| Recruiting | Aerobic Exercise and Its Impact on Sensory, Musculoskeletal, and Psychosocial Aspects in Migraine NCT06716489 | University of Sao Paulo | N/A |
| Not Yet Recruiting | Localized Injection of Lidocaine Via the Middle Meningeal Artery for Intractable Headache Treatment NCT07361549 | Daniel A Tonetti, MD | Phase 2 |
| Not Yet Recruiting | Filter Lenses for the Prevention of Migraine Attacks NCT06161129 | Rune Skovgaard Rasmussen | N/A |
| Not Yet Recruiting | Amylin-Induced Migraine Attacks Without Aura NCT07340788 | Danish Headache Center | N/A |
| Recruiting | Infusion of Lidocaine and Steroids in Middle Meningeal Artery for Pain in Subarachnoid Hemorrhage NCT07294118 | The University of Texas Medical Branch, Galveston | Phase 2 |
| Active Not Recruiting | Prediction Model for Postoperative Headache After Transsphenoidal Pituitary Surgery NCT07446036 | Beijing Tiantan Hospital | — |
| Enrolling By Invitation | App-based Breathing Program for Migraine Relief NCT07297901 | Arizona State University | N/A |
| Not Yet Recruiting | LLM-Generated Lay Summaries for Brain MRI Reports NCT07310394 | University Hospital, Lille | N/A |
| Recruiting | Concussion Recovery and Support Program NCT07097792 | Seattle Children's Hospital | N/A |
| Recruiting | Efficacy and Safety of Transcutaneous Auricular Vagus Nerve Stimulation for Postoperative Headache Following S NCT07479082 | Beijing Tiantan Hospital | N/A |
| Completed | Ultrasonographic Optic Nerve Sheath Diameter in Postdural Puncture Headache Diagnosis NCT07100158 | Ankara City Hospital Bilkent | — |
| Not Yet Recruiting | Turkish Version of the Headache Screening Questionnaire NCT07048132 | Başakşehir Çam & Sakura City Hospital | — |
| Not Yet Recruiting | Effects of Photobiomodulation With Superpulsed Laser and Dual Wavelengths in Children and Adolescents NCT07031505 | University of Nove de Julho | N/A |
| Completed | The Effect of Sphenopalatine Ganglion Block on Headache and Vasalgia NCT07060586 | University Hospital Bispebjerg and Frederiksberg | N/A |
| Completed | The Relationship Between Smartphone Use and Headache and Posture Disorders in University Students NCT06996964 | Bahçeşehir University | — |
| Not Yet Recruiting | 0.5% Bupivacaine Lower Cervical Intramuscular Injection vs IV Medications for Headache Treatment NCT06937385 | HCA Florida North Florida Hospital | Phase 3 |
| Recruiting | Placebo Impacts Sleep and Pain Modulation in Chronic Pain NCT06225817 | University of Maryland, Baltimore | N/A |
| Not Yet Recruiting | Can a Specific OMT Protocol Influence Patient Pain and Associated Analgesia Use for Primary Headache Disorders NCT06546462 | New York Institute of Technology | N/A |
| Enrolling By Invitation | The Effectiveness of CBD and CBN in the Treatment of Facial Pain and Headache of Muscular Origin NCT05961501 | Wroclaw Medical University | Phase 2 / Phase 3 |
| Not Yet Recruiting | Effect of Parcetamol in Headach NCT06861738 | Assiut University | Phase 3 |
| Recruiting | Lidocaine Infusion Treatment for Subarachnoid Hemorrhage Headaches NCT06582810 | University of Kansas Medical Center | — |
| Enrolling By Invitation | The BETY-Biopsychosocial Questionnaire (BETY-BQ) in Individuals With Temporomandibular Dysfunction-Related Hea NCT05902026 | Hasan Kalyoncu University | — |
| Active Not Recruiting | Sphenopalatine Ganglion Block and Cold Induced Headaches NCT06310200 | Wright State University | Phase 1 |
| Recruiting | Puberty, Testosterone, and Brain Development NCT06670053 | University of Colorado, Denver | — |
| Not Yet Recruiting | Postdural Puncture Headache After Spinal Anesthesia for Cesarean Section NCT06683807 | Assiut University | N/A |
| Recruiting | External Trigeminal Nerve Stimulation for Migraine Treatment in Pregnancy NCT06788977 | Cefaly Technology | — |
| Completed | Headache in Juvenile Onset Systemic Lupus Erythematosus NCT06658457 | Pamukkale University | — |
| Recruiting | Transnasal Sphenopalatine Ganglion Block for Treatment of Acute Subarachnoid Hemorrhage Associated Headache NCT06621329 | University of California, Davis | Phase 2 / Phase 3 |
| Recruiting | THE EFFECT OF SURGICAL MASK AND N95 MASK USE ON SURGICAL SMOKE IN OPERATING ROOM NURSES NCT07404956 | Bartın Unıversity | N/A |
| Completed | Safety and Efficacy Predimenol for Headache NCT06558006 | Dexa Medica Group | Phase 2 |
| Completed | Sphenopalatine Ganglion Block for Post-Dural Puncture Headache NCT07494383 | ISSSTE Hospital Regional "Gral. Ignacio Zaragoza" | N/A |
| Recruiting | Intranasal Sphenopalatine Ganglion Blockade for Headaches Following Aneurysmal Subarachnoid Hemorrhage NCT07116408 | Wright State University | Phase 4 |
| Recruiting | The Effect of Osteopathic Treatment on Craniocervico-Mandibular Dysfunction NCT06471426 | Edward Via Virginia College of Osteopathic Medicine | N/A |
| Unknown | Arabic Version Of Henry Ford Hospital Headache Disability Inventory Questionnaire : Validity, And Reliability NCT06125821 | Cairo University | — |
| Unknown | Impementation of the Exercise Recommendations for the Treatment of Primary Headaches: A Qualitative Approach t NCT06127888 | Fundació Universitària del Bages | — |
| Recruiting | Personalized Brain Stimulation to Treat Chronic Concussive Symptoms NCT06073886 | University of California, Los Angeles | Phase 2 |
| Completed | Combine Effect Of Myofascial Release Technique and Ocular Muscle Exercise Among University Students NCT06406881 | Riphah International University | N/A |
| Completed | Cross-cultural Adaptation, Reliability and Validity of the Turkish Version of the Headache Disability Question NCT04736654 | Gazi University | — |
| Recruiting | Headache Registration and Followup Initiated by Tongji Hospital, HUST NCT07269561 | Tongji Hospital | — |
| Completed | Relation Between Forward Head Posture and Incidence of Headache in Obese Adults NCT06383429 | Ahram Canadian University | — |
| Completed | Investigation of the Relationship Between Gray and White Matter Volumes, Walking Exercise, and Body Fat Percen NCT07425093 | Amasya University | N/A |
| Recruiting | BLOCK-SAH - PPF-Block for Post-SAH Headache NCT06008795 | University of Florida | Phase 2 |
| Unknown | Sequential, Multiple Assignment, Double Randomized Preference, Migraine Behavioral Trial NCT06170281 | Stanford University | N/A |
| Completed | The Use of Virtual Reality Applications in Tension-Type Headaches NCT06155669 | Ankara City Hospital Bilkent | N/A |
| Unknown | Migraine Headache Mitigation Utilizing Avulux NCT06149000 | Kaiser Permanente | N/A |
| Recruiting | Repetitive Transcranial Magnetic Stimulation for Post-concussion Headaches NCT06112093 | State University of New York - Upstate Medical University | Phase 1 |
| Completed | Efficacy of Manuel Therapy and BETY in Patients With Temporomandibular Dysfunction Related Headache NCT05927545 | Hasan Kalyoncu University | N/A |
| Completed | Bioequivalence Study to Compare Ibuprofen/ Paracetamol Tablets (200mg Ibuprofen/ 500mg Paracetamol) Versus Nur NCT06180070 | Humanis Saglık Anonim Sirketi | Phase 1 |
| Recruiting | Responding With Evidence and Access for Childhood Headaches NCT05889624 | Children's Hospital Medical Center, Cincinnati | N/A |
| Completed | Study of Two Digital Therapeutics for the Prevention of Episodic Migraine Receiving CGRP Therapy (ReMMiD-C) NCT06004388 | Click Therapeutics, Inc. | Phase 3 |
| Recruiting | Differences in Characteristics of Headache Patients With a Positive or Negative FRT: a Cross-sectional Compari NCT06134791 | University Ghent | — |
| Completed | Effect of Electromagnetic Therapy on Patients With Chronic Rhinosinusitis. NCT05865613 | Cairo University | N/A |
| Recruiting | Evaluation of the Efficacy of Manual Therapy, Therapeutic Exercise and the Two Modalities Combined in Pain Red NCT05990153 | Campus Bio-Medico University | N/A |
| Completed | Study of Two Digital Therapeutics for the Prevention of Episodic Migraine NCT05853900 | Click Therapeutics, Inc. | N/A |
| Completed | Greater Occipital Nerve Pulsed Radiofrequency in Cervicogenic Headache NCT06764433 | Ankara City Hospital Bilkent | N/A |
| Completed | Steroids in Occipital Nerve Block for Treatment of Headache NCT05732532 | Mayo Clinic | Phase 4 |
| Completed | The U.K. Embryologist Fatigue Study NCT05708963 | TMRW Life Sciences | — |
| Unknown | Occipital Nerve RF Between Occipital Nerve Block And Occipital Nerve Radiofrequency Ablation NCT04124458 | Allevio Pain Management Clinic | N/A |
| Completed | Vagal Nerve Stimulation for Post COVID Fatigue NCT05445427 | Mayo Clinic | N/A |
| Unknown | A Wearable Nerve Stimulator for Chronic Migraine/Headache and Mood Disturbance in Adolescents NCT05702528 | University of South Carolina | N/A |
| Completed | Cross-cultural Adaptation, Reliability and Validity of the Turkish Version of the Headache Impact Questionnair NCT04765501 | Gazi University | — |
| Unknown | Validity and Reliability of the Dutch HDI NCT05619354 | University Ghent | — |
| Completed | Effect of Riocigaut on Cerebral Vasodilation and Headache Induction in Healthy Volunteers NCT05582811 | Danish Headache Center | N/A |
| Completed | Transnasal Versus Suprazygomatic SPG Block in Persistant Idiopathic Facial Pain NCT06496841 | Diskapi Teaching and Research Hospital | — |
| Withdrawn | Safe Harbors in Emergency Medicine, Specific Aim 3 NCT05410366 | Vanderbilt University Medical Center | — |
| Unknown | Validity of Headache Disability Index NCT05376163 | Hacettepe University | — |
| Unknown | The Involvement of ATP Sensitive Potassium Channel in Migraine Aura and Migraine Pain. NCT05565001 | Danish Headache Center | N/A |
| Unknown | Superficial Dry Needling for Cervicogenic Headache NCT05444296 | Youngstown State University | N/A |
| Recruiting | Determining the Utility of a Behavioral Intervention in Chronic Migraine NCT05415020 | Mayo Clinic | N/A |
| Completed | RELAXaHEAD for Headache Patients (Phase II) NCT05466682 | NYU Langone Health | N/A |
| Completed | Alleviation of Common Cold Symptoms NCT06106880 | Applied Biological Laboratories Inc | Phase 1 |
| Completed | The Effect of Accompanying Temporomandibular Joint Dysfunction in Patients With Chronic Migraine NCT05381129 | Istanbul University - Cerrahpasa | N/A |
| Completed | The U.S. Embryologist Fatigue Study NCT05326802 | TMRW Life Sciences | — |
| Completed | Efficacy of GONB in Patients of Migraine NCT05679765 | Pain Medicine Department | Phase 4 |
| Completed | Kinesiophobia in Children With Headaches NCT06136052 | Istanbul Arel University | — |
| Withdrawn | Sphenopalatine Ganglion Block for the Treatment of Post-Stroke Headache NCT05365880 | University of Utah | Phase 2 |
| Recruiting | Percutaneous Needle Electrolysis (PNE) on the Concha of the Ear NCT05662722 | University of Alcala | N/A |
| Completed | Effect of Sumatriptan on Levcromakalim-Induced Symptoms in Individuals With Migraine NCT05211050 | Danish Headache Center | N/A |
| Completed | Temporamandibular Joint Functions and Parafunctional Habits NCT05580276 | Karadeniz Technical University | — |
| Unknown | Dry Needling of the M. Obliquus Capitis Inferior on Rotational Mobility and Headache Related Outcome Measures NCT05074381 | University Ghent | N/A |
| Completed | Effect of Low Level Laser Therapy in Patients With Chronic Rhinosinusitis. NCT05861817 | Cairo University | N/A |
| Completed | New-onset Severe Headache After Covid-19 Vaccine NCT05235776 | Oslo University Hospital | — |
| Recruiting | Combined Transcranial Magnetic Stimulation and Therapy for MTBI Related Headaches NCT05176392 | Veterans Medical Research Foundation | N/A |
| Unknown | The Incidents of Weekend Headaches in Children NCT05218330 | Bnai Zion Medical Center | — |
| Active Not Recruiting | Effect of Hormones on Frequency of Headache and Brain Structure and Function in Puberty NCT05607303 | University of Colorado, Denver | — |
| Completed | Evaluating the Effectiveness of a Headache Management Program in Primary Care Settings NCT05067725 | Geisinger Clinic | N/A |
| Unknown | Dry Needling for Cervicogenic Headache NCT05140291 | Youngstown State University | N/A |
| Completed | Comparison of Kinesiology Taping and Instrument Assisted Soft Tissue Mobilization in Cervicogenic Headache NCT05474612 | Riphah International University | N/A |
| Completed | Mirtazapine vs Sumatriptan in the Treatment of Postdural Puncture Headache NCT05108688 | Ain Shams University | Phase 4 |
| Completed | Art Therapy QEEG Study for Service Members with a Traumatic Brain Injury and Posttraumatic Stress Symptoms NCT04776304 | Walter Reed National Military Medical Center | N/A |
| Completed | Neurolens Headache Study NCT05070767 | Neurolens Inc. | N/A |
| Unknown | Pediatric Patient Experience on a Diagnostic Path NCT05199363 | Children's Memorial Health Institute, Poland | N/A |
| Unknown | Home Blood Pressure Monitoring Before and After COVID-19 Vaccination in Patients at High Risk of Cardiovascula NCT05033613 | National Taiwan University Hospital | — |
| Completed | Treatment of Chronic Cluster Headache with TENS and ONS NCT05023460 | University of Aarhus | N/A |
| Terminated | Efficacy of CLORazepate for the Treatment of MIGraine Attack in the Emergency Room NCT04726592 | Assistance Publique - Hôpitaux de Paris | Phase 3 |
| Completed | Effect of Ivabradine on Levcromakalim-Induced Symptoms in Individuals With Migraine Without Aura (ILIM) NCT04853797 | Danish Headache Center | N/A |
| Completed | Migraine in Electrohypersensitive Patients NCT04845152 | University Hospital, Montpellier | — |
| Completed | Amitriptyline vs GON and SON Blocks in Migraine NCT04750967 | Dr. Lutfi Kirdar Kartal Training and Research Hospital | N/A |
| Recruiting | Assessment of the Efficacy of Medrol Dose Pack for Acute Post-Concussive Headaches NCT04685772 | Northwell Health | — |
| Terminated | Sphenopalatine Ganglion Block for Headache After Concussion NCT04650282 | University of Michigan | Phase 2 |
| Completed | Investigating the Frequency and Phenotype of Headaches Associated With Fasting During the Month of Ramadan. NCT04804995 | Danish Headache Center | — |
| Recruiting | Mind Body Balance for Pediatric Migraine NCT04715685 | Children's Hospital Medical Center, Cincinnati | N/A |
| Completed | Study of Hesperidin Therapy on COVID-19 Symptoms (HESPERIDIN) NCT04715932 | Montreal Heart Institute | Phase 2 |
| Unknown | Comparison Of Different Doses Of Intrathecal Neostigmine In Prevention Of Post-Dural Puncture Headache NCT04905953 | Cairo University | Phase 2 / Phase 3 |
| Completed | Early Vascular Ageing in the YOUth NCT04598685 | VASCage GmbH | — |
| Terminated | The Effect of Ganglion Sphenopalatine Block Versus Placebo on Persistent Headache Following COVID-19 Infection NCT04636034 | University Hospital Bispebjerg and Frederiksberg | Phase 3 |
| Completed | Instrument-assisted Soft Tissue Mobilization and Phonophoresis on Trigger Points of Tension Headache NCT04950413 | Nada Gamal Saad | N/A |
| Unknown | Lokal Cold Application in Nitroglycerin-Induced Headache (NIH) NCT04707586 | Yasemin Kalkan Uğurlu | N/A |
| Completed | Narrow Band Green Light and Migraine NCT04841083 | Vedanta Research | N/A |
| Completed | Temporomandibular Dysfunction Affects Neck Disability, Headache, Anxiety, And Sleep Quality In Women: A Cross- NCT04948320 | Ankara Yildirim Beyazıt University | — |
| Completed | Efficacy of Percutaneous SPG Block in Aneurysmal SAH NCT04331938 | Mayo Clinic | Phase 1 |
| Unknown | Registry for Migraine - Structural and Functional MRI Before and After Erenumab Treatment NCT04674020 | Danish Headache Center | Phase 4 |
| Completed | Predictive Score for Non-traumatic Secondary Headache After an Emergency Call NCT04617808 | Centre Hospitalier Régional d'Orléans | — |
| Completed | The Hemodynamic Effects of PACAP38 After Glibenclamide Administration in Healthy Volunteers NCT04960657 | Danish Headache Center | N/A |
| Completed | Implementation of a Minor Ailment Service in Community Pharmacy Practice NCT05247333 | Universidad de Granada | N/A |
| Unknown | miR-155 Expression in Episodic and Chronic Migraine NCT05891808 | IRCCS National Neurological Institute "C. Mondino" Foundation | — |
| Unknown | A Diagnostic Test on DeepDoc-an AI-based Decision Support System NCT04055766 | Xijing Hospital | — |
| Unknown | The TMS Treatment for Postoperative Headache in GH Tumor NCT04529356 | Huashan Hospital | N/A |
| Completed | Brain Structural Abnormalities in Patients with Post-COVID-19 Headache NCT06825741 | University of Pecs | — |
| Unknown | Safety Profile of PETALO CVS in the Treatment of Non-thrombotic Internal Jugular Vein Stenosis and Chronic Hea NCT04352218 | University of Catania | Phase 2 |
| Completed | Anchoring Patients Pain Scores in the Emergency Department NCT04717518 | CHRISTUS Health | — |
| Completed | CorPath® GRX Neuro Study NCT04236856 | Corindus Inc. | N/A |
| Completed | Effectiveness of Acupuncture Clinical Pathway NCT04490798 | Hospital Son Llatzer | — |
| Completed | Effects of Manual Therapy on the Upper Cervical Spine Combined With Exercise vs Isolated Exercise in Patients NCT04401501 | Universidad de Zaragoza | N/A |
| Completed | Improvement of Migraine Severity and Frequency With Migraineguard ™ NCT04759040 | Herbacure Natural | N/A |
| Unknown | The Effect of Intravenous Fluid Therapy in Acute Migraine Attacks NCT04287140 | Marmara University | N/A |
| Unknown | Musculoskeletal Impairment in Headaches Attributed to Rhinosinusitis NCT04222244 | Des Moines University | — |
| Unknown | SPG Blocks for Headaches NCT04255420 | Kendall Healthcare Group, Ltd. | Phase 4 |
| Completed | Dry Needling for Cervicogenic Headache NCT04305223 | Emory University | N/A |
| Completed | Acute Headache Treatment in Pregnancy: Occipital Nerve Block vs PO Acetaminophen With Caffeine NCT03951649 | University of Alabama at Birmingham | Phase 4 |
| Completed | The Hemodynamic Effects of CGRP After Glibenclamide Administration in Healthy Volunteers NCT04231617 | Danish Headache Center | N/A |
| Completed | Factors Affecting Patients With Myofascial Temporomandibular Disorders NCT04842136 | Hasan Kalyoncu University | — |
| Unknown | Xuefu-Zhuyu Capsule for the Treatment of "Qizhi Xueyu Zheng" (Qi Stagnation and Blood Stasis Syndrome) NCT04218487 | Zhong Wang | Phase 4 |
| Completed | Headache Provocation of People Who Are Unable to Have Headache NCT04217668 | Danish Headache Center | N/A |
| Completed | Prevention and Intervention of Neck Pain in Swiss Office-Workers NCT04169646 | Zurich University of Applied Sciences | N/A |
| Completed | Evaluation of the Impact of the HL Natural, Inc. Tension Relief Product NCT04091555 | Hawthorne Effect Inc. | N/A |
| Completed | Multiomics After Headache Provocation of People Who Are Unable to Have Headache NCT04218760 | Danish Headache Center | N/A |
| Unknown | Long Term Efficacy of Neuronavigation Guided rTMS in Alleviating Gulf War Illness Related Headaches and Pain S NCT04182659 | Veterans Medical Research Foundation | N/A |
| Completed | Pain Perception of People Who Are Unable to Have Headache NCT04217616 | Danish Headache Center | — |
| Completed | Multiomics After Cold Pressor Test of People Who Are Unable to Have Headache NCT04220580 | Danish Headache Center | N/A |
| Completed | Evaluation of Headache and Childbirth in a Chronic Pain Population NCT04632420 | Stanford University | — |
| Completed | Magnesium Versus Prochlorperazine Versus Metoclopramide for Migraines NCT05967442 | Wake Forest University Health Sciences | Phase 3 |
| Completed | Headache Inducing Effect of Levcromakalim in Migraine With Aura Patients NCT04012047 | Danish Headache Center | N/A |
| Completed | Acupuncture as Migraine Prophylaxis in Reducing Frequency, Duration and Intensity of Migraine With Minimum Acu NCT04509141 | Indonesia University | N/A |
| Completed | Evaluation of a Fixed Combination of Herbal Extracts to Prevent Symptoms Alcohol-induced Hangovers NCT04183842 | Incara Lab | N/A |
| Completed | Improving Safety of Diagnosis and Therapy in the Inpatient Setting NCT04393909 | Brigham and Women's Hospital | N/A |
| Suspended | Efficacy of a Transcranial Vibrating System for Mitigation of Migraine Associated Vertigo NCT03886012 | Otolith Labs | N/A |
| Unknown | The Hemodynamics Effect of Glibenclamide on Levcromakalim Assessed by High Resolution Magnetic Resonance Angio NCT03886922 | Danish Headache Center | N/A |
| Unknown | Pulsed Radiofrequency in Chronic Headaches NCT04339335 | Attikon Hospital | — |
| Completed | the Effectiveness of 3rd Occipital Radiofrequency Versus Systemic Steroid in Headache Management in Rheumatoid NCT03852355 | Assiut University | N/A |
| Completed | Effectiveness of Yoga@Work to Reduce Head and Muscle Pain in Office Workers NCT04313491 | Aarogyam UK | N/A |
| Withdrawn | Drinking Extra Water for to Prevent or Decrease Headaches NCT02330809 | ThinkWell | N/A |
| Completed | Post-dural Puncture Headache: A Retrospective Study NCT03790124 | Augusta University | — |
| Completed | Neurology Inpatient Clinical Education Trial NCT03826056 | Dartmouth-Hitchcock Medical Center | N/A |
| Completed | Ultrasound Guided Platelet Rich Plasma Injections for Post Traumatic Greater Occipital Neuralgia NCT04051203 | University of Calgary | Phase 1 |
| Completed | Influence of Dalcroze Eurhythmics on Pains in Older Women NCT06264102 | Poznan University of Physical Education | N/A |
| Completed | Cervical Stabilization Training on Individuals With Headache NCT05839496 | Gazi University | N/A |
| Completed | Effects of Preemptive Paracetamol and Ibuprofen on Headache and Myalgia in Patients After Electroconvulsive Th NCT03783312 | Inonu University | N/A |
| Completed | SubArachnoid Hemorrhage HEadache Treated by Lumbar Puncture NCT03754335 | University Hospital, Toulouse | N/A |
| Completed | Mechanisms Of Change in Adolescent Pain Self-management NCT04043962 | Seattle Children's Hospital | N/A |
| Completed | Mind and Body Approaches to Pain Reduction in Youth With Migraine NCT03472092 | Children's Hospital Medical Center, Cincinnati | Phase 2 |
| Unknown | Collection of Whole Blood Samples for the Evaluation of Preeclampsia (Pre-E) Biomarkers From Pregnant Women NCT03767803 | Progenity, Inc. | — |
| Completed | Impact of Exercise on "Invisible" Symptoms and Quality of Life in Multiple Sclerosis Individuals NCT03768830 | University of Rijeka | N/A |
| Completed | Provider-Targeted Behavioral Interventions to Prevent Unsafe Opioid Prescribing for Acute Pain in Primary Care NCT03537573 | University of Pittsburgh | N/A |
| Completed | The Role of Inflammation and Vasodilatation in PACAP38-induced Headache Using MRI on Healthy Subjects NCT03585894 | Danish Headache Center | N/A |
| Completed | Adverse Events in Dry Needling NCT03612843 | Elizabeth Lane | — |
| Completed | The Effect of Levcromakalim Infusion on the Cranial Arteries Over Several Hours Using a High Resolution MRA Te NCT03609008 | Danish Headache Center | N/A |
| Completed | Headache After Coil Embolization for Unruptured Intracranial Aneurysms NCT03359252 | Seoul National University Hospital | N/A |
| Completed | Dexmedetomidine and Propofol for Pediatric MRI Sedation NCT03513757 | Medical College of Wisconsin | Phase 4 |
| Completed | Headache Analysis and Intervention NCT02887638 | Hasselt University | N/A |
| Unknown | Endovascular Stenting Treatment for Patients With Internal Jugular Vein Stenosis NCT03373292 | Capital Medical University | Phase 1 |
| Unknown | Neuroinflammatory Response and Headache Control in Patients After Subarachnoid Hemorrhage NCT03604276 | MaineHealth | — |
| Completed | RELAXaHEAD for Headache Patients (Phase I) NCT03183791 | NYU Langone Health | N/A |
| Withdrawn | Cognitive Effects of Immediate Release Topiramate vs Extended Release Topiramate in Patients With Migraine NCT03280342 | University of Minnesota | Phase 2 |
| Completed | The Effect of OMT on Functional Outcomes and Anti-inflammatory Biomarkers in Mild to Moderate Traumatic Brain NCT03163901 | Michigan State University | N/A |
| Withdrawn | A Comparative Efficacy Trial of IV Acetaminophen Versus IV Ketorolac for Emergency Department Treatment of Gen NCT03472872 | Corewell Health South | Phase 4 |
| Terminated | Acupuncture - a Treatment for Children With Headache NCT03426800 | Regionshospital Nordjylland | N/A |
| Completed | The Effectiveness of Osteopathic Manipulative Medicine in the Management of Headaches Associated With Post Con NCT04732338 | Hackensack Meridian Health | EARLY_Phase 1 |
| Completed | Sphenopalatine Ganglion Block Versus Occiptal Nerve Block in Treatment of Post Dural Puncture Headache NCT03156049 | Assiut University | N/A |
| Completed | Immediate Effect of Energy Alignment and Mantra on Stress Related Pain in Adolescents NCT03308630 | NMP Medical Research Institute | N/A |
| Withdrawn | Facilitating Migraine Medication Adherence and Optimizing Medication Use NCT02473692 | Wake Forest University Health Sciences | — |
| Terminated | LSFG-SKIN, Laser Speckle Flowgraphy NCT03660618 | Randy Kardon | N/A |
| Completed | Intravenous Fluids in Benign Headaches Trial NCT03185130 | University Medical Center of Southern Nevada | Phase 4 |
| Completed | rTMS Treatment of Persistent Headache and Post Concussion Symptoms Attributed to Mild Traumatic Injury to the NCT03691272 | University of Calgary | Phase 1 / Phase 2 |
| Completed | S100B in the Care of Non-traumatic Headaches in the Emergency Department NCT02683304 | Centre Hospitalier Universitaire de Nīmes | N/A |
| Completed | The Effect of Intravenous L-kynurenine (LKYN) on Cerebral Hemodynamics in Healthy Volunteers NCT03212430 | Danish Headache Center | Phase 1 |
| Completed | Alleviating Headache and Pain in GWI With Neuronavigation Guided rTMS NCT03030794 | Veterans Medical Research Foundation | N/A |
| Terminated | Treatment of Post-dural Puncture Headache in Postpartum Patients: Sphenopalatine Ganglion Block to Epidural Bl NCT02962427 | University of Colorado, Denver | Phase 4 |
| Unknown | Assessment of Siemens' GoBrain and DotBrain Software NCT03269539 | University of Saskatchewan | — |
| Terminated | Effects of IV-Administered Ca-DTPA and Zn-DTPA To Treat Patients With Gadolinium Deposition Disease NCT02947022 | University of North Carolina, Chapel Hill | Phase 1 / Phase 2 |
| Withdrawn | Neuromodulation Treatment of Vestibular Migraines NCT02866084 | University of Miami | N/A |
| Completed | Confounding Factors in the Detection of Intracranial Hemorrhage With the Infrascanner NCT02809651 | Ziekenhuis Oost-Limburg | N/A |
| Terminated | The CHECK Trial: A Comparison of Headache Treatment in the Emergency Department: Compazine Versus Ketamine NCT02735343 | Mike O'Callaghan Military Hospital | Phase 3 |
| Completed | Olanzapine for Acute Headaches NCT03066622 | HealthPartners Institute | Phase 4 |
| Completed | "THINK Trial: Treatment of Headache With IntraNasal Ketamine: A Randomized Controlled Trial Evaluating the Eff NCT03081416 | Brooke Army Medical Center | Phase 3 |
| Completed | The Association Between Pain Catastrophizing Scale Score and Postspinal Headache NCT02727244 | Tokat Gaziosmanpasa University | — |
| Completed | The CHECK Trial: A Comparison of Headache Treatment in the ED: Compazine Versus Ketamine NCT02657031 | University Medical Center of Southern Nevada | Phase 4 |
| Terminated | Interventional Testing of Gene-environment Interactions Via the Verifomics Mobile Application NCT02758990 | Verifomics LLC | N/A |
| Completed | Ketamine for Acute Migraine in the Emergency Department NCT02697071 | Carilion Clinic | N/A |
| Completed | Chronic Postconcussive Headache: A Placebo-Controlled Treatment Trial of Prazosin NCT02266329 | VA Office of Research and Development | Phase 1 / Phase 2 |
| Unknown | Non-pharmacological Management of Chronic Migraine NCT02953015 | Universita di Verona | N/A |
| Withdrawn | A Comparison of Dexamethasone and Triamcinolone for Ultrasound-guided Occipital C2 Nerve Blocks NCT02655523 | Northwestern University | Phase 4 |
| Completed | Vitamin D Plasma Level and Its Role in Headache NCT02467127 | University of Catanzaro | N/A |
| Completed | Ticagrelor Therapy for RefrACTORy Migraine Study NCT02518464 | Columbia University | Phase 4 |
| Completed | IV Haloperidol for the Treatment of Headache in the ED NCT02747511 | Western Michigan University School of Medicine | Phase 4 |
| Unknown | Yoga for Pediatric Tension-Type Headache NCT03166358 | Matthew Morris | N/A |
| Unknown | Clinical Decision Rule for Pediatric Intracranial Pathology NCT02742272 | Children's Hospitals and Clinics of Minnesota | — |
| Completed | Prospective Analgesic Compound Efficacy (PACE) Study NCT02403687 | Express Specialty Pharmacy | — |
| Unknown | PatientSpot Formerly Known as ArthritisPower NCT03840928 | Global Healthy Living Foundation | — |
| Completed | A Preliminary Investigation of the Efficacy of Aromatherapy in Reducing Discomfort in Youth With Chronic Heada NCT02440997 | Children's Mercy Hospital Kansas City | N/A |
| Completed | eNeura SpringTMS Post-Market Observational US Study of Migraine NCT02357381 | eNeura, Inc. | — |
| Unknown | Maintenance of Anaesthesia With Sevoflurane Versus Propofol and the Occurrence of Postoperative Headache. NCT03789370 | Attikon Hospital | N/A |
| Completed | Comparative Study Between Hydrocortisone and Mannitol in Treatment of Postdural Puncture Headache NCT02760862 | Ain Shams University | Phase 4 |
| Completed | An Intervention to Improve Adolescent Headache Self-management NCT02475005 | Stephen F Butler, PhD | N/A |
| Completed | Acceptance and Commitment Therapy vs Medical Treatment as Usual Wait-list Control for Primary Headache Suffere NCT02734992 | University of Cyprus | N/A |
| Unknown | Comparing Sensory Modulation, Anxiety and Quality of Life Between Children With Primary Headaches and Healthy NCT04284501 | Bnai Zion Medical Center | — |
| Withdrawn | Efficacy and Safety of a Fixed-dose Combination of Naratriptan and Naproxen in Acute Treatment of Migraine. NCT01726920 | Ache Laboratorios Farmaceuticos S.A. | Phase 3 |
| Completed | The Effect of Patient Position on Postdural Puncture Headache NCT02122419 | Diskapi Yildirim Beyazit Education and Research Hospital | — |
| Completed | Effects of Fasting on Self Efficacy NCT02113111 | Universität Duisburg-Essen | — |
| Completed | A Retrospective Chart Review to Evaluate Diagnosis and Treatment of Chronic Migraine and Headache NCT01946126 | Allergan | — |
| Completed | Carbon Monoxide's Headache Inducing Characteristics and Effects on the Cerebral Arteries and Blood Flow NCT02066558 | Danish Headache Center | N/A |
| Completed | Clinical Effects of Upper Cervical Translatoric Mobilization in Patients With Headache NCT02422862 | Universidad de Zaragoza | N/A |
| Completed | Scalp Block Versus Scalp Infiltration With Dexmedetomidine and Local Anesthetic for Post Craniotomy Pain NCT02866409 | NAVNEH SAMAGH | Phase 2 |
| Completed | GET Living: Graded Exposure Treatment for Children and Adolescents With Chronic Pain NCT01974791 | Boston Children's Hospital | N/A |
| Completed | Use of Ibuprofen and Acetaminophen for Treatment of Acute Headache Post Concussion in Children NCT02268058 | McMaster Children's Hospital | N/A |
| Withdrawn | Effects of Perioperative Pregabalin for Post-Craniotomy Pain NCT01591980 | Unity Health Toronto | Phase 4 |
| Unknown | Effects of Changes in Dietary Intake and Headache's Attacks NCT01917474 | Federico II University | N/A |
| Completed | Migraine With Aura Inducing Characteristics and Effects on the Cerebral Arteries and Blood Flow by Hypoxia NCT01896167 | Danish Headache Center | N/A |
| Completed | Promoting Patient-Centered Counseling to Reduce Inappropriate Diagnostic Tests NCT01808664 | University of California, Davis | N/A |
| Unknown | Prevalence of Post-craniotomy Headache in Siriraj Hospital NCT01806155 | Mahidol University | — |
| Completed | Evaluation of an Integrated Care Project NCT01854580 | Charite University, Berlin, Germany | — |
| Completed | Acetazolamide's Headache Inducing Characteristics and Effects on the Cerebral Arteries and Blood Flow NCT01750723 | Danish Headache Center | N/A |
| Completed | Exercise and Manipulative Therapy for Older Persons With Headache NCT01736774 | Chiang Mai University | N/A |
| Unknown | Correlation Between Headaches and Septum and Nasal Mucosa Contact NCT01943929 | Hospital Israelita Albert Einstein | — |
| Completed | Sphenopalatine Nerve Block for Headache Tx360 NCT01939314 | Indiana University | Phase 3 |
| Completed | Exercise Training With Physically Active Lifestyle to Reduce Headache and Quality of Life NCT01664585 | UKK Institute | N/A |
| Completed | Natriuretic Peptide's Headache Inducing Characteristics and Effects on the Cerebral Blood Flow NCT01637662 | Danish Headache Center | N/A |
| Unknown | Inflammatory Markers Identification in Migraine Patients NCT01618201 | Tel-Aviv Sourasky Medical Center | — |
| Completed | Safety and Efficacy of Botulinum Toxin Type A (BOTOX®) to Treat Chronic Migraine in Korea NCT01976611 | Allergan | — |
| Terminated | The Childhood and Adolescent Migraine Prevention Study NCT01581281 | Children's Hospital Medical Center, Cincinnati | Phase 3 |
| Completed | Problem Solving Skills Training For Parent Caregivers of Youth With Chronic Pain NCT01496378 | Seattle Children's Hospital | N/A |
| Completed | STOPAIN in the Treatment of a Single Migraine Attack NCT01687101 | Thomas Jefferson University | N/A |
| Terminated | Efficacy of a Single Dose of Aspirin vs. Acetaminophen in Tension Type Headache NCT01552798 | Bayer | Phase 3 |
| Completed | A Study of the Safety and Efficacy of MK-6096 for Migraine Prophylaxis in Participants With Episodic Migraine NCT01513291 | Merck Sharp & Dohme LLC | Phase 2 |
| Completed | Non-drug Interventions for Migraines NCT01545466 | Brigham and Women's Hospital | N/A |
| Unknown | Will the Use of Osteopathic Manipulative Treatments Help Alleviate Headache Pain NCT01704625 | Good Samaritan Hospital Medical Center, New York | N/A |
| Completed | Outcomes After Surgery for Degenerative Cervical Radiculopathy in Patients with Concurrent Headache NCT06885216 | University Hospital of North Norway | — |
| Completed | A Cost Effective Treatment for Headache in Pregnancy When Acetaminophen Alone is Ineffective. NCT02295280 | St. Louis University | N/A |
| Withdrawn | Efficacy and Safety of a Fixed-dose Combination of Naratriptan and Naproxen in Acute Treatment of Migraine NCT01390324 | Ache Laboratorios Farmaceuticos S.A. | Phase 3 |
| Completed | Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of Care NCT01431326 | Daniel Benjamin | — |
| Completed | HIRREM Developmental Study NCT02709369 | Wake Forest University Health Sciences | N/A |
| Completed | Pain Quality Study NCT01321190 | University of Washington | — |
| Completed | Internet Intervention for Adolescents With Chronic Pain NCT01316471 | Seattle Children's Hospital | Phase 2 |
| Completed | Cervical Spine Manipulation Affects on Balance and Proprioception NCT01745705 | University of Nevada, Las Vegas | N/A |
| Completed | Effect of Osteopathic Manipulative Treatment for Patients With Chronic Headache NCT01332864 | Western University of Health Sciences | Phase 4 |
| Completed | Exploratory Study to Evaluate 2 Acupuncture Methods for the Treatment of Headaches Associated With TBI NCT01338701 | Samueli Institute for Information Biology | Phase 2 / Phase 3 |
| Completed | Effect of Transmagnetic Stimulation on Conditioned Pain Modulation (CPM) NCT01501045 | Rambam Health Care Campus | N/A |
| Completed | Botulinum Toxin Type A in Treatment of Cranial Allodynia in Patients With Headache NCT01357798 | Federal University of Bahia | Phase 3 |
| Completed | Efficacy Evaluation Of Great Occipital Nerve Electrical Stimulation On Rebound Headache NCT01184222 | Centre Hospitalier Universitaire de Nice | N/A |
| Completed | Clinical Evaluation of QFlu Combo Test NCT01506583 | Cellex, Inc. | — |
| Completed | Boston Migraine and Contraception Study NCT01216358 | Planned Parenthood League of Massachusetts | — |
| Unknown | Efficacy and Safety Study to Compare Ibuprofen + Caffeine With Ibuprofen Alone in the Treatment of Headache NCT01172405 | Mantecorp Industria Quimica e Farmaceutica Ltd. | Phase 3 |
| Completed | Prostaglandin F2alpha in a Human Headache Model NCT01327118 | Danish Headache Center | N/A |
| Completed | Study of Oculomotor Dysfunction Leading to Children Vertigo NCT01153789 | Assistance Publique - Hôpitaux de Paris | N/A |
| Completed | Neural Dynamics and Connectivity in Response Inhibition and Traumatic Brain Injury NCT01194661 | National Institute of Neurological Disorders and Stroke (NINDS) | — |
| Completed | Intravenous Fluid for Pediatric Migraine in the Emergency Department NCT01073787 | University of Alberta | Phase 1 / Phase 2 |
| Completed | Trial of Etoricoxib (Arcoxia) Taken Prophylactically to Prevent Ramadan Headache NCT01148303 | Hartford Hospital | Phase 4 |
| Completed | Equity in Diagnostic Imaging Trial NCT01611714 | Icahn School of Medicine at Mount Sinai | N/A |
| Terminated | Low Dose Versus Usual Dose Dexamethasone for Symptom Control in Children Undergoing Cranial or Craniospinal Ra NCT01135550 | The Hospital for Sick Children | Phase 3 |
| Completed | Mindfulness-Based Cognitive Therapy for the Treatment of Chronic Headache Pain NCT01213056 | University of Alabama, Tuscaloosa | Phase 1 / Phase 2 |
| Completed | A Study of Family-based Cognitive-behavioral Therapy for Chronic Pediatric Headache and Anxiety NCT01182051 | Johns Hopkins University | N/A |
| Completed | Healing Patient Rooms NCT01504750 | Maastricht University Medical Center | N/A |
| Completed | Metoclopramide Versus Ketorolac for Tension-type Headache NCT01011673 | Montefiore Medical Center | Phase 4 |
| Terminated | A Study to Evaluate the Efficacy and Safety of IV Peramivir in Addition to Standard of Care Compared to Standa NCT00958776 | BioCryst Pharmaceuticals | Phase 3 |
| Completed | Safety Study of IV Peramivir in Hospitalized Subjects With Confirmed or Suspected Influenza NCT00957996 | BioCryst Pharmaceuticals | Phase 3 |
| Completed | A Clinical Trial of the Optimal Treatment Period and Long-term Efficacy of Functional Electrical Stimulation ( NCT01000389 | Medotech A/S | N/A |
| Withdrawn | A Study Comparing Two Spinal Techniques for for Cesarean Delivery Anesthesia NCT00990574 | Stanford University | N/A |
| Unknown | Identification of Inflammatory Markers in Migraine Patients NCT00969995 | Tel-Aviv Sourasky Medical Center | — |
| Completed | Utility of the History and Physical Exam in the Emergency Department NCT01154517 | Henry Ford Health System | — |
| Completed | MedlinePlus Health Prescriptions: Developing a Pragmatic Approach for Clinic Use NCT01050465 | University of Missouri-Columbia | N/A |
| Completed | Digital Ocular Fundus Photography in the Emergency Department: A New Application for Telemedicine? NCT00873613 | Emory University | N/A |
| Unknown | Tailored Internet Information Supply for Patients NCT00746408 | Health & Life Sciences University, Tryol | — |
| Completed | Oxygen Therapy for the Treatment of Undifferentiated Headache in the Emergency Department NCT00856232 | University of Medicine and Dentistry of New Jersey | N/A |
| Completed | Validation of Venogenic Hypothesis for Cough, Exertional and Sexual Headaches NCT00852748 | French Society for the Study of Migraine Headache | — |
| Completed | Study of Intramuscular Ropivacaine Injections for Treatment of Pediatric Headache NCT00680823 | Robert Hickey | N/A |
| Completed | Effect of a New Oral Contraceptive Pill on Hormone Related Symptoms Such as Pelvic Pain and Headache NCT00778609 | Bayer | Phase 3 |
| Withdrawn | Is Topiramate Effective in Treating Dizziness in Patient's With Migraine-Associated Dizziness NCT00732108 | University of California, San Francisco | N/A |
| Unknown | Randomized Placebo Controlled Trial With Etoricoxib That is Taken to Prevent the Yom Kippur Headache NCT00752921 | Shaare Zedek Medical Center | Phase 4 |
| Withdrawn | MgSO4 vs Metoclopramide for Headache in Pregnant Women NCT00632606 | Women and Infants Hospital of Rhode Island | Phase 2 / Phase 3 |
| Terminated | Evaluation of Yoga for the Treatment of Pediatric Headaches NCT00726843 | Medical College of Wisconsin | N/A |
| Terminated | Medical Therapies for Chronic Post-Traumatic Headaches NCT00862095 | Madigan Army Medical Center | Phase 4 |
| Terminated | Rhinogenic Headache Improvement After Nasal Operation NCT00580307 | University of Missouri-Columbia | N/A |
| Completed | Carbachols Headache-inducing Effect and Changes in Cerebral Blood Flow in Migraine Patients NCT00564408 | Danish Headache Center | N/A |
| Completed | Web-based CBT for Children With Chronic Pain NCT00853138 | Seattle Children's Hospital | Phase 2 |
| Completed | Pomegranate Products for Prevention of Common Cold NCT00617318 | Texas Heart Institute | Phase 3 |
| Completed | Efficacy and Safety of Sinutab on Subjects in the Setting of a Common Cold NCT00378144 | McNeil AB | Phase 4 |
| Unknown | Juvenile Postlumbar Puncture Headache After Puncture With Needles With Quincke Tip or With Sprotte Tip NCT00450060 | Heidelberg University | N/A |
| Unknown | Migraine Inducing Effects and Changes in Brain Haemodynamics of PGI2 NCT00510172 | Glostrup University Hospital, Copenhagen | N/A |