Trials / Completed
CompletedNCT04598685
Early Vascular Ageing in the YOUth
Early Vascular Ageing in the YOUth - An Observational Study Into the Predictors of Atherosclerotic Changes in Adolescents
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 1,517 (actual)
- Sponsor
- VASCage GmbH · Academic / Other
- Sex
- All
- Age
- 14 Years – 19 Years
- Healthy volunteers
- Accepted
Summary
This is a single-center observational study on adolescents to determine predictors of the early steps of the formation of atherosclerosis and to quantify their influence on Intima-Media-Thickness of the carotid artery and the aorta and on the Pulse-Wave Velocity. A long-term follow-up by means of record linkage is furthermore planned to evaluate the effect of early atherosclerosis and the cardiovascular risk profile on future morbidity with a special focus cardio- and cerebrovascular events.
Detailed description
EVA4YOU is a cross-sectional study enrolling 3000 students and apprentices aged between 14 and 19 years. Examinations are conducted at schools and companies throughout Tyrol, Austria and include laboratory measurements; standardized medical interviews; anthropometry; liver elastography; ultrasonography of the carotid artery and the aorta, and blood pressure, bioelectrical impedance; visceral abdominal fat-tissue-thickness measurement, pulse-wave velocity measurements. The study hypothesis is that the cardiovascular risk factors measured already influence the formation of atherosclerosis (measured as carotid and aortic Intima-Media Thickness and Pulse-Wave-Velocity) in adolescents. A long-term follow-up by means of record linkage is furthermore planned to evaluate the effect of early atherosclerosis and the cardiovascular risk profile on future morbidity with a special focus cardio- and cerebrovascular events.
Conditions
- Atherosclerosis
- Cardiovascular Risk Factor
- Cardiovascular Diseases
- Cardiovascular Pathology
- Life Style
- Vascular Diseases
- Vascular Stiffness
- Non-Alcoholic Fatty Liver Disease
- Hypertension
- Obesity
- Overweight
- Headache
- Sleep
- Sleep Disorder
Timeline
- Start date
- 2021-02-01
- Primary completion
- 2023-02-28
- Completion
- 2023-03-31
- First posted
- 2020-10-22
- Last updated
- 2023-05-12
Locations
1 site across 1 country: Austria
Source: ClinicalTrials.gov record NCT04598685. Inclusion in this directory is not an endorsement.