NCT01011673

Metoclopramide Versus Ketorolac for Tension-type Headache

An RCT of Metoclopramide/Diphenhydramine vs. Ketorolac Alone for Tension-type Headache

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 123 (actual)
• Sponsor: Montefiore Medical Center · Academic / Other
• Sex: All
• Age: 21 Years – 64 Years
• Healthy volunteers: Not accepted

Summary

Occasionally, episodic tension-type headache may be severe enough to require an emergency department (ED) visit. The purpose of this study is to compare two commonly used medications to see which is better for tension type headache. Patients who present to the ED with an acute tension-type headache requiring treatment with injectable medication will be randomized to metoclopramide or ketorolac.

Conditions

• Headache

Interventions

Type	Name	Description
DRUG	Metoclopramide	metoclopramide 20mg IVSS + diphenhydramine 25mg IVSS
DRUG	Ketorolac	ketorolac 30mg IVSS

Timeline

• Start date: 2009-11-01
• Primary completion: 2012-09-01
• Completion: 2012-11-01
• First posted: 2009-11-11
• Last updated: 2018-05-15
• Results posted: 2012-12-03

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated drug study