NCT04182659

Long Term Efficacy of Neuronavigation Guided rTMS in Alleviating Gulf War Illness Related Headaches and Pain Symptoms

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 150 (estimated)
• Sponsor: Veterans Medical Research Foundation · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

This study aims to look at the long term efficacy of using repetitive transcranial magnetic stimulation (rTMS) in relieving Gulf War Illness related headaches and pain.

Detailed description

Headaches (HA), muscle and joint pain, are some of the most common debilitating symptoms in military personnel served in the 1990-1991 Persian Gulf War (GW1). Migraine like HA and diffuse body pain were detected in 64% of Gulf War Veteran (GWV) diagnosed with Gulf War Illness (GWI). Unfortunately, conventional pharmacological treatments for GWI-related pain has not been shown to be effective and drugs such as narcotics contain many long term untoward psychosomatic and abusive side effects. This study is assessing the effectiveness of repetitive transcranial magnetic stimulation (rTMS), non-invasive treatment option, in alleviating headaches, muscle, and joint pain symptoms of GWI.

Conditions

• Gulf War Syndrome
• Gulf War Illness
• Headache
• Muscle Pain
• Joint Pain

Interventions

Type	Name	Description
DEVICE	Transcranial Magnetic Stimulation	A non-invasive treatment that emits magnetic pulses to stimulate the brain.
DEVICE	Sham Transcranial Magnetic Stimulation	Sham rTMS will consist of the same parameters as active, however, the subject will not receive the actual magnetic stimulation due to the use of a double sided Active/Sham coil used specifically for research studies.

Timeline

• Start date: 2019-10-01
• Primary completion: 2023-09-30
• Completion: 2023-09-30
• First posted: 2019-12-02
• Last updated: 2023-08-09

Locations

3 sites across 1 country: United States

Regulatory

• FDA-regulated device study