| Not Yet Recruiting | Penn SICCA Follow-up Study NCT05056012 | University of Pennsylvania | — |
| Not Yet Recruiting | Autologous Serum Tears With Hyaluronate vs Balanced Salt Solution for Moderate-to-Severe Dry Eye NCT07413172 | University of Miami | Phase 2 |
| Not Yet Recruiting | A Study to Evaluate the Safety, Tolerability, and Pharmacokinetic Profile of RC017 Ophthalmic Ointment Followi NCT07521748 | Nanjing Reju Therapeutics Co., Ltd | Phase 1 |
| Enrolling By Invitation | Microbiome-Focused Food Supplement for Evaporative Dry Eye Due to Meibomian Gland Dysfunction NCT07453212 | Varol TUNALI | N/A |
| Not Yet Recruiting | Study of Blinking as a Function of Tear Film Quality NCT07499193 | Essilor International | N/A |
| Not Yet Recruiting | Lacrima VR for Dry Eye Disease and Meibomian Gland Dysfunction NCT07415330 | Demaod Ltd | N/A |
| Completed | Effect of Yellow Light AG Mobile Phone Screen on Dry Eye and Asthenopia. NCT07340359 | Second Affiliated Hospital, School of Medicine, Zhejiang University | N/A |
| Not Yet Recruiting | Telemedicine for Evaluating Dry Eye Disease (DED) Using a Mobile Phone-Attached Portable Automatic Ocular Surf NCT07341724 | Singapore National Eye Centre | N/A |
| Not Yet Recruiting | Study to Evaluate the Safety and Tolerability of PRO-190 Ophthalmic Solution Compared to Systane Ultra® on the NCT06379685 | Laboratorios Sophia S.A de C.V. | Phase 1 |
| Not Yet Recruiting | Switching From Xiidra to TRYPTYR NCT07267481 | Southern College of Optometry | Phase 4 |
| Recruiting | Single-Arm Study of a Treatment for Dry Eye in People Who Struggle to Wear Contact Lenses NCT07510620 | Vision Innovation Centers of Pennsylvania, LLC d/b/a Eye Care Specialists | Phase 4 |
| Recruiting | PCOS and Problem of Eye Dryness: Is There a Benefit From Lifetyle Changes NCT07366944 | Cairo University | N/A |
| Not Yet Recruiting | Switching From Restasis to TRYPTYR NCT07267299 | Southern College of Optometry | Phase 4 |
| Recruiting | JN002 for the Treatment of Dry Eye Disease NCT07245017 | Eye & ENT Hospital of Fudan University | EARLY_Phase 1 |
| Recruiting | Comparing Tear Proteomics Profile in Dry Eye Disease pre-and Post-treatment With Low Level Light Therapy NCT07329712 | Singapore National Eye Centre | — |
| Recruiting | Impact of TRYPTYR on a Patient's Quality of Life and Ability to Perform Work NCT07266948 | Southern College of Optometry | Phase 4 |
| Recruiting | Preliminary Clinical Study of the Effectiveness and Safety of Ocular Surface Microbiota Transplantation in the NCT07298811 | Second Affiliated Hospital of Nanchang University | Phase 1 / Phase 2 |
| Recruiting | An Eight-Week Study to Evaluate the Safety and Efficacy of VSJ-110 Compared to Placebo in the Treatment of Dry NCT07179055 | Vanda Pharmaceuticals | Phase 2 |
| Completed | Effect of a Dietary Supplement on Gut Microbiota and Ocular Surface Outcomes in Dry Eye Disease NCT07148271 | Varol TUNALI | N/A |
| Not Yet Recruiting | Phase III Study of Topical Fibrinogen-Depleted Human Platelet Lysate Compared to Placebo for Moderate to Sever NCT06903611 | Cambium Bio Limited | Phase 3 |
| Enrolling By Invitation | Evaluation of New Color Temperature Adjustment Mode in Preventing Dry Eye and Visual Fatigue NCT07201493 | Beijing Tongren Hospital | N/A |
| Completed | Phase 2b Controlled Study of Dosing Techniques - Part B NCT07161011 | IVIEW Therapeutics Inc. | Phase 2 |
| Active Not Recruiting | Evaluation of the Protective Effects of Cordyceps Cicadae on Visual Function and Anti-Fatigue Performance in E NCT07135193 | China Medical University Hospital | N/A |
| Recruiting | Efficacy of Kera Sol Tears on Signs and Symptoms of Surgical Temporary Ocular Discomfort Syndrome (STODS) in S NCT07155070 | Vance Thompson Vision | Phase 4 |
| Not Yet Recruiting | Compare the Clinical Efficacy of 3% Diquafosol and 0.1% Hyaluronic Acid in Patients With Dry Eye After LASIK NCT07097922 | He Eye Hospital | N/A |
| Not Yet Recruiting | Impact of Cataract Surgery on the Incidence and Progression of Dry Eye Disease NCT06759168 | Assiut University | — |
| Recruiting | Quality of Life in Presbyopic Patients Who Are Treated With Qlosi NCT07113210 | Southern College of Optometry | Phase 4 |
| Completed | A Study to Evaluate Concomitant Perfluorohexyloctane Use With Contact Lens Wear NCT07054606 | Bausch & Lomb Incorporated | Phase 4 |
| Not Yet Recruiting | Ganyan-1 in Dry Eye NCT06818487 | Beijing Tongren Hospital | N/A |
| Active Not Recruiting | Exploring the Eye Care Benefits of Cordyceps Cicadae Across Different Age Groups NCT07135180 | China Medical University Hospital | N/A |
| Recruiting | SAS 1: Develop Ocular Disease (OSD) Diagnostic, Algorithms, and Management Protocols for Cataract Surgery NCT07323264 | Louis Tong | — |
| Recruiting | Low Level Light Therapy & Skin Pigmentation NCT07173530 | University of Houston | N/A |
| Terminated | Performance of Systane PRO Versus Refresh Optive Mega-3 NCT06975891 | Scripps Poway Eyecare and Optometry | Phase 4 |
| Not Yet Recruiting | Efficacy of Lipid-containing Artificial Tears in the Treatment of Dry Eye NCT06955585 | University Hospital Sestre Milosrdnice | N/A |
| Recruiting | Assessment of CataClear, Tear Film Stability, Tear Volume, and Dry Eye Symptoms Using Stem Cells Fortified Eye NCT07191847 | Ace Cells Lab Limited | Phase 4 |
| Recruiting | Evaluating the Efficacy of Topical Insulin for the Restoration of Ocular Surface Interface in Dry Eye Disease. NCT06939959 | Khyber Teaching Hospital | Phase 4 |
| Not Yet Recruiting | Comparing Efficacy of Tea Tree Oil Versus Topical Azithromycin in Treating Dry Eye NCT06921525 | Ehab Mohamed Elsayed Mohamed Saad | Phase 1 / Phase 2 |
| Active Not Recruiting | Comparing Effect of Hyaluronic Acid and Lipid Coated Carbomer Gel on Dry Eyes After Phacoemulsification in DP NCT06901895 | Superior University | N/A |
| Recruiting | Cord Blood Platelet Poor Plasma Eye Drops NCT07089511 | Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico | N/A |
| Recruiting | Effect of Addition of Pyramidal Exercise to Intermittent Fasting on Dryness of Eye in Pre-diabetic Psoriasis P NCT06893913 | Cairo University | N/A |
| Not Yet Recruiting | Compare the Clinical Efficacy of 3% Diquafosol and 0.1% Hyaluronic Acid in Patients with Dry Eye After Trans-P NCT06852105 | He Eye Hospital | N/A |
| Recruiting | Role of Corneal Nerves in Dry Eye Disease NCT06841471 | Daniela Nosch | — |
| Recruiting | Use of Acthar Gel Single-Dose Pre-Filled SelfJectTM Injector in Patients With Moderate-Severe Keratitis and Au NCT06964269 | Toyos Clinic | Phase 4 |
| Completed | AI Chatbot-Based Learning on Dry Eye and Eye Strain Knowledge NCT06785155 | Gaziantep Islam Science and Technology University | N/A |
| Completed | Prostaglandin Analog Eyelash Serum and Ocular Surface Health: A Prospective Study NCT06875687 | University of Seville | N/A |
| Completed | Effect of Low-Level Light Therapy on Ocular Surface Parameters in Patients Undergoing Cataract Surgery NCT07067294 | Grigore T. Popa University of Medicine and Pharmacy | N/A |
| Recruiting | Evaluation of BTV100 in Subjects With Dry Eye Disease NCT06543303 | BioTheraVision, Inc. | Phase 2 |
| Completed | Efficacy and Safety of SJP-0132 Eye Drops in Chinese Patients With Dry Eye Disease NCT06717152 | Senju Pharmaceutical Science & Technology (Beijing) Co., Ltd. | Phase 3 |
| Completed | A Study in the Treatment of Mild to Moderate Dry Eye Disease Comparing Saline to TTAX03. NCT06780306 | BioTissue Holdings, Inc | Phase 2 |
| Recruiting | Eyelid Closure in Keratometry NCT07297849 | Vienna Institute for Research in Ocular Surgery | N/A |
| Completed | A Randomized Controlled Trial to Evaluate the Safety and Efficacy of an Oral Supplement in Supporting Vision a NCT07123584 | Bio Nature Health | N/A |
| Completed | Evaluation of Safety and Efficacy of DM-28 for Treatment of Moderate to Severe Ocular Dryness NCT06607237 | Horus Pharma | N/A |
| Enrolling By Invitation | Efficacy of 0.28% Sodium Hyaluronate Eye Drops in Patient With Moderate to Severe Dry Eye NCT06860659 | Department of Medical Services Ministry of Public Health of Thailand | Phase 4 |
| Not Yet Recruiting | Effects of 3% Diquafosol on Tear Film and Vision-related Quality of Life in Orthokeratology Lens Related Dry E NCT06537349 | He Eye Hospital | N/A |
| Completed | Effect of Low-Level Light Therapy on Ocular Surface Parameters in Patients Undergoing Femto-Lasik Surgery NCT07181668 | Grigore T. Popa University of Medicine and Pharmacy | N/A |
| Not Yet Recruiting | iTear Single-center, Open-label, Single-arm Study NCT06525961 | The University of Hong Kong | Phase 4 |
| Active Not Recruiting | A Study to Evaluate Corneal Endothelial Cell Density (ECD) in Subjects With Dry Eye Disease (DED) Administerin NCT06565650 | Bausch & Lomb Incorporated | Phase 4 |
| Recruiting | Dryness Difference Between Before and After Phacoemulsification NCT06513000 | Sohag University | — |
| Terminated | Differences in Corneal Structure and Function in Patients With Sjogrens vs. Non-Sjogrens Dry Eye NCT06364657 | Johns Hopkins University | — |
| Completed | An Observational Study to Assess Optive MEGA-3 (OM3) on Dry Eye Symptoms and Quality of Life of Adult Particip NCT06439394 | AbbVie | — |
| Completed | An Observational Study to Assess Next Generation Emulsion Preservative Free Eye Drops (NGE-UD) on Dry Eye Symp NCT06443775 | AbbVie | — |
| Completed | Dry Eye and Asthenopia Treatment Effect Evaluation. NCT06763822 | Second Affiliated Hospital, School of Medicine, Zhejiang University | N/A |
| Recruiting | Clinical Investigation for a Multifunction Ophthalmic Measurement Device NCT06565091 | Essilor International | N/A |
| Completed | Corneal Changes in Estrogen-Dependent Breast Cancer After Hormonal Treatment NCT06924229 | Sohag University | Phase 4 |
| Completed | Treating Lid Wiper Epitheliopathy NCT06671041 | Southern College of Optometry | Phase 4 |
| Terminated | Study to Evaluate Corneal Neurosensory Abnormalities in Patients With Sjögren's Dry Eye NCT06411132 | Dompé Farmaceutici S.p.A | — |
| Not Yet Recruiting | Assessment of Tear Production, Corneal Staining, and Comfort Level Wearing Different Types of Contact Lenses NCT06351410 | National University of Malaysia | N/A |
| Suspended | A Study to Evaluate the Efficacy and Safety of Tanfanercept (HL036) in Dry Eye Disease NCT06400589 | HanAll BioPharma Co., Ltd. | Phase 3 |
| Completed | A Study to Evaluate the Effect of Miebo™ on Preoperative Biometry/Keratometry and Postoperative Refractive Acc NCT06346340 | Bausch & Lomb Incorporated | Phase 4 |
| Recruiting | Cyclosporine and Intense Pulsed Light for Dry Eye in Contact Lens Users NCT06392438 | Université de Sherbrooke | Phase 3 |
| Completed | Total30 For Contact Lens Dropouts NCT06967298 | Southern College of Optometry | N/A |
| Completed | YM-101 Eye Drops in the Treatment of Dry Eye Syndrome NCT06792903 | Eye & ENT Hospital of Fudan University | EARLY_Phase 1 |
| Completed | The THINK Study Incidence of Neurotrophic Keratopathy) NCT06482164 | Research Insight LLC | N/A |
| Recruiting | Study of 5% VVN001 Ophthalmic Solution in Dry Eye Disease NCT06360133 | VivaVision Biotech, Inc | Phase 3 |
| Unknown | Neurological Dry Eye Study Stimulating Both Lacrimal and Vagus Nerves NCT06271005 | Genetic Disease Investigators | N/A |
| Completed | Healthy Living Through Personalized Monitoring of Eyelid Care NCT03840668 | Singapore National Eye Centre | N/A |
| Completed | Evaluation of the Efficacy and Safety of DM934 Versus Théalose on Eye Dryness NCT06245421 | Horus Pharma | N/A |
| Not Yet Recruiting | Efficacy of 20% Autologous Serum Drops in the Treatment of Corneal Epitheliopathy Associated With Antihyperten NCT06294015 | Université de Sherbrooke | Phase 4 |
| Unknown | A Study to Evaluate the Safety and Efficacy of VSJ-110 Compared to Placebo in the Treatment of Dry Eye NCT06296966 | Vanda Pharmaceuticals | Phase 2 |
| Completed | A Study to Evaluate Early Treatment Outcomes With Miebo™ in Subjects With Dry Eye Disease NCT06309953 | Bausch & Lomb Incorporated | Phase 4 |
| Active Not Recruiting | The Effect of Omega 3 Supplements Comparison With Warm Compression in Patients With Dry Eye Disease NCT06748768 | Superior University | — |
| Unknown | Point of Care Test of LTA Level in Tear Fluid, Measured With a POCT Test, in DE Patients Following IPL Treatme NCT06269237 | He Eye Hospital | N/A |
| Terminated | A Study Evaluating the Safety of the Nasal Pump NCT06329687 | Oyster Point Pharma, Inc. | Phase 4 |
| Completed | Hydroxypropyl-methylcellulose and GlicoPro® Eyedrops in the Treatment of Dry Eye Disease: Clinical Study NCT06726525 | University of Milan | Phase 4 |
| Active Not Recruiting | Comparing Efficacy of Autologous Serum Eye Drops With and Without Insulin in Autoimmune Dry Eye: A Randomized NCT06931041 | Instituto de Oftalmología Fundación Conde de Valenciana | Phase 3 |
| Unknown | PET-CT Imaging Features of Meibomian Glands NCT06324890 | Zhongnan Hospital | — |
| Completed | Subjective and Objective Performance of Systane Complete Multi-Dose PF Versus Walgreen's Lubricant Balance NCT06219577 | Scripps Poway Eyecare and Optometry | Phase 4 |
| Completed | Medical vs Acupuncture for Dry Eye NCT07185854 | Nadide Koca | N/A |
| Withdrawn | Tear Film Markers in Dry Eye Syndrome NCT04515329 | Vishal Jhanji | Phase 4 |
| Completed | Validity of Web-Based OSDI-6 Questionnaire in a Chinese Adult Population NCT06158906 | He Eye Hospital | — |
| Completed | Efficacy and Safety of Different Hyaluronic Acid Tear Substitutes Formulations in Evaporative Dry Eye NCT06517667 | University of Seville | Phase 2 / Phase 3 |
| Unknown | Comparison of Non-pharmaceutical Treatments for Evaporative Dry Eye NCT05923528 | He Eye Hospital | N/A |
| Completed | Systane® Ultra Preservative Free Lubricant Eye Drops NCT05902364 | Alcon Research | N/A |
| Completed | The COAT Trial: Cequa's Onset of Action Trial NCT06482177 | Research Insight LLC | Phase 4 |
| Completed | Systane® Hydration PF and Systane® Hydration Preserved NCT05932238 | Alcon Research | N/A |
| Completed | Managing Dry Eye in Patients Using Glaucoma Drops NCT06158984 | He Eye Hospital | N/A |
| Completed | Performance and Safety of T2769 in DED NCT05965778 | Laboratoires Thea | N/A |
| Active Not Recruiting | Effect of Periorbital Massage on Dry Eye Disease NCT06390644 | Superior University | N/A |
| Completed | Evaluation of Miebo (Perfluorohexyloctane) Eyedrops in Habitual Contact Lens Wearers NCT06176651 | Gordon Schanzlin New Vision | Phase 4 |
| Recruiting | The Effect of Cord Blood Serum Eyes Drops Administer in Patients With Severe Keratopathy Related to EGFR-I Tre NCT06830551 | IRCCS Azienda Ospedaliero-Universitaria di Bologna | N/A |
| Completed | Efficacy of Quantum Molecular Resonance Combined With Intense Pulsed Light in Mixed Dry Eye NCT06576245 | University of Seville | N/A |
| Unknown | The Effect of a Pre-cataract Surgical Ocular Hygiene Regime on Microbial Load, Tear Osmolarity, Dry Eye, and I NCT05990712 | Uptown Eye Specialists | Phase 4 |
| Completed | Systane® Complete Preservative Free Lubricant Eye Drops NCT05932225 | Alcon Research | N/A |
| Completed | Performance and Safety Assessment of T2769 in Contact Lens Wearers With Dry Eye Symptoms. NCT05931861 | Laboratoires Thea | N/A |
| Completed | Impact of Different Types of Virtual Reality Games on Motion Sickness and Ocular in Adults: A Pilot Study NCT06354309 | He Eye Hospital | N/A |
| Completed | A Prospective Study of the Dry Eye Drink That Evaluates Hydration and Subject's Assessment on Eye Dryness NCT05949697 | Bruder Healthcare | N/A |
| Completed | Feasibility of Dynamic Muscle Stimulation + Radiofrequency for Improving Blink Quality in Subjects with Dry Ey NCT05945069 | Lumenis Be Ltd. | N/A |
| Active Not Recruiting | The Beijing Adult Dry Eye Cohort Study NCT06621446 | Beijing Tongren Hospital | — |
| Completed | Comparing Efficacy and Safety of TJO-083 in Dry Eye Diseases Patients NCT06427031 | Taejoon Pharmaceutical Co., Ltd. | Phase 3 |
| Completed | Efficacy and Safety of a Multiple-Action Tear Substitute (TriMix) in Dry Eye Disease NCT06478134 | University of Seville | Phase 2 / Phase 3 |
| Completed | Phase 4 Study Evaluating the Safety of the Nasal Guide With Tyrvaya NCT05918406 | Oyster Point Pharma, Inc. | Phase 4 |
| Unknown | Croatian Version of the Ocular Surface Disease Index Questionnaire (OSDI) NCT05938985 | University Hospital Sestre Milosrdnice | — |
| Completed | Evaluation of Low-Level Light Therapy on Meibomian Glands Study NCT05859295 | University of Houston | N/A |
| Completed | Combined Treatment With Pulsed Light and Photobiomodulation Before Laser Refractive Surgery NCT05803798 | University Hospital, Brest | N/A |
| Completed | Intra-Nasal Mechanical Stimulation (INMEST) As a Treatment Method for the Relief of Symptoms of Dry Eye NCT05887336 | Abilion Medical Systems AB | N/A |
| Unknown | Platelet Rich Plasma in Corneal Surface Diseases NCT05320172 | Assiut University | Phase 3 |
| Withdrawn | OSIG-eye Drops Treatment for Dry Eye Disease NCT04510428 | University of Illinois at Chicago | Phase 2 |
| Completed | Dry Eye Symptom Mitigation by Oral Intake of Probiotics NCT05906381 | Chung Shan Medical University | N/A |
| Completed | Evaluate the Safety and Efficacy of Calcitonin Gene-Related Peptide (CGRP) Antagonists in Patients With Dry Ey NCT05895500 | Nvision Laser Eye Centers | — |
| Completed | Nasal Spray Study in Sjogren's Dry Eye Disease NCT05700422 | University of Pennsylvania | Phase 4 |
| Completed | Evaluation of Comfort of Ocular Lubricants in Symptomatic Contact Lens Wearers NCT05741216 | Alcon Research | N/A |
| Completed | Study of OT202 in Treating Moderate to Severe Dry Eye NCT06435182 | Ocumension Therapeutics (Shanghai) Co., Ltd | Phase 2 |
| Unknown | Temperature on Evaporative Dry Eye NCT05720754 | He Eye Hospital | N/A |
| Unknown | Function and Morphological Characteristics of Meibomian Gland in Patients With Renal Anemia NCT06287879 | Zhongnan Hospital | N/A |
| Completed | Evaluating a Device for Blocking the Tear Duct NCT05748951 | AesculaTech, Inc. | N/A |
| Completed | Management of DE With IPL in Combination With DQS NCT05694026 | He Eye Hospital | N/A |
| Completed | Clinical Evaluation of a Multidose Preservative-free Lubricating Eye Drops Contained in Novelia® Eye Dropper i NCT05661851 | Johnson & Johnson Vision Care, Inc. | Phase 2 |
| Recruiting | Clinical Trial to Determine the Efficacy and Safety of Insulin Eye Drops in Dry Eye in Patients with Topical H NCT06017362 | Barbara Burgos Blasco | Phase 4 |
| Completed | Artificial Tears, Tear Lipids and Tear Film Dynamics NCT05705518 | University of California, Berkeley | Phase 4 |
| Active Not Recruiting | DOMPE -MT Neurotrophic Keratitis NCT06947850 | Toyos Clinic | Phase 4 |
| Completed | Evaluation of Safety and Tolerability of Ocular Lubricants NCT05573360 | Alcon Research | N/A |
| Completed | Effect of Micropulse Laser on Dry Eye Disease Due to Meibomian Gland Dysfunction NCT04425551 | Naval Hospital, Athens | N/A |
| Completed | PMCF Study to Evaluate Performance and Safety of "Xanoftal Next" NCT05829499 | C.O.C. Farmaceutici S.r.l. | N/A |
| Recruiting | The Effect of Eyeliner on Tear Composition, Tear Secretion and Tear Film Stability. NCT05632887 | Zhongnan Hospital | — |
| Completed | Quantum Molecular Resonance Electrotherapy in Severe Dry Eye Disease NCT06119386 | Centro Oculistico Borroni | N/A |
| Unknown | Changes of Clinical Characteristics and Tear Film Biomarkers Following FS-LASIK NCT05601011 | Peking University Third Hospital | — |
| Completed | Efficacy of 0.38% and 0.18% Sodium Hyaluronate Ocular Lubricants for Dry Eye in Adult Gazan Participants NCT06851364 | International Islamic University Malaysia | Phase 2 |
| Unknown | Clinical Characteristics of Patients Developing Chronic Dry Eye After Refractive Surgery NCT05600985 | Peking University Third Hospital | — |
| Completed | Clinical Trial To Determine The Effectiveness And Safety Of Topical Insulin In Dry Eye NCT05692739 | Barbara Burgos Blasco | Phase 4 |
| Recruiting | Electroacupuncture for Mild-to-moderate Dry Eye NCT05552820 | Shanghai Institute of Acupuncture, Moxibustion and Meridian | N/A |
| Unknown | Safety, Tolerability, Plug Retention and Preliminary Efficacy of Tacrolimus-loaded Punctal Plug in Patients Wi NCT05618730 | Eximore Ltd. | Phase 1 |
| Completed | Evaluation of Onefit Scleral Lenses in the Mangement of Dry Eye NCT05973409 | CooperVision International Limited (CVIL) | N/A |
| Completed | Lifitegrast 5% for the Treatment of Dry Eye In Habitual Soft Contact Lens Wearers NCT05505292 | State University of New York College of Optometry | Phase 4 |
| Completed | to Evaluate the Effectiveness and Safety of the Tixel® , VS LipiFlow® in the Treatment of Meibomian Gland Dysf NCT05162261 | Novoxel Ltd. | N/A |
| Terminated | Effects of Supplementation With PUFAs and Antioxidants for Contact Lens Discomfort NCT04163328 | University of Alabama at Birmingham | Phase 4 |
| Completed | Prospective Single-center Long-term Follow-up Study of a Series of Cases Previously Included in the QUALVIDON NCT05523531 | Fondation Ophtalmologique Adolphe de Rothschild | — |
| Completed | PMCF Study to Evaluate Performance and Safety of "HPMC-based Eyedrops" Used to Relieve Dry Eye Symptoms NCT05825599 | C.O.C. Farmaceutici S.r.l. | N/A |
| Unknown | The Effect of 0.05% CsA Eye Drops on Post-refractive Surgery Dry Eye NCT06043908 | Peking University Third Hospital | Phase 4 |
| Completed | Bilberry-containing Capsules for Dry Eye Mitigation NCT05737108 | Chung Shan Medical University | N/A |
| Completed | Efficacy and Safety Safety of Nutritears® in Adults With Dry Eye Syndrome NCT05481450 | Applied Science & Performance Institute | N/A |
| Unknown | To Evaluate the Efficacy of Diquafosol Sodium in the Treatment of MGD in Different Treatment Pattern NCT05383612 | Zhongshan Ophthalmic Center, Sun Yat-sen University | N/A |
| Completed | PMCF Study to Evaluate Performance and Safety of "Distilled Waters-based Eyedrops" Used to Relieve Dry Eye Sym NCT05825586 | C.O.C. Farmaceutici S.r.l. | N/A |
| Completed | Phase 2, Multi-center, Randomized, Double- Masked and Placebo-Controlled Study of YP-P10 Ophthalmic Solution C NCT05467293 | Yuyu Pharma, Inc. | Phase 2 |
| Completed | PMCF Study to Evaluate Performance and Safety of "Hyaluronic Acid (HA)-Based Eyedrops" Used to Relieve Dry Eye NCT05807360 | C.O.C. Farmaceutici S.r.l. | N/A |
| Completed | PMCF Study to Evaluate Performance and Safety of "CLHA-based Eyedrops" Used to Improve Lacrimal Abnormalities NCT05823961 | C.O.C. Farmaceutici S.r.l. | N/A |
| Completed | PMCF Study to Evaluate Performance and Safety of "Optrex Double Action Soothing and Lubricating Drops" NCT05824000 | C.O.C. Farmaceutici S.r.l. | N/A |
| Completed | Cyclosporine 0.1% / Loteprednol 0.2% Effect on Anterior Segment Normalization NCT05322148 | Research Insight LLC | Phase 3 |
| Completed | AST Combined With 0.05% Cyclosporin Eye Drop Improve Corneal Nerve Density in Patients With SS Dry Eye NCT06013436 | Chengdu University of Traditional Chinese Medicine | — |
| Completed | Dailies Total 1 Sphere Contact Lenses NCT05239494 | University of Alabama at Birmingham | N/A |
| Completed | Ocular Effects of Scleral Lens Wear on Dry Eye Patients NCT05079321 | University of Waterloo | N/A |
| Completed | Herbal Medication to Treat Dry Eye in Peri/ Post-menopausal Women NCT05319041 | Singapore National Eye Centre | EARLY_Phase 1 |
| Completed | Efficacy of Low-Level Light Therapy in Reducing Dry Eye in Patients Undergoing Cataract Surgery NCT05754437 | Azienda Ospedaliera Universitaria Mater Domini, Catanzaro | N/A |
| Completed | Tear Lipid Layer Thickness Assessments With Perfluorohexyloctane Eye Drops NCT05288582 | Ohio State University | N/A |
| Completed | PMCF Study to Evaluate Performance and Safety of "Ocular Drops Based Upon Carmellose" Used to Relieve Dry Eye NCT05825352 | C.O.C. Farmaceutici S.r.l. | N/A |
| Unknown | Usability, Immediate, and 30 Day Effect of External Neuromodulation With iTEAR100 Generation 2 in Dry Eye Pati NCT05304637 | Olympic Ophthalmics, Inc. | Phase 4 |
| Unknown | Evaluating Impact of Systane iLux on Dryness Symptoms and Wearing Time in Contact Lens Users NCT05306561 | Periman Eye Institute | N/A |
| Completed | Safety and Efficacy Study on Cenegermin (Oxervate®) vs Vehicle in Severe Sjogren's Dry Eye Disease (PROTEGO-1 NCT05133180 | Dompé Farmaceutici S.p.A | Phase 3 |
| Unknown | Dry Eye Response to Interval Exercise and Mediterranean Diet NCT05248698 | Cairo University | N/A |
| Completed | Total30 Sphere Contact Lenses NCT05183022 | University of Alabama at Birmingham | N/A |
| Completed | Phase II Clinical Study to Evaluate the Efficacy of Multidose Lagricel® Ofteno Ophthalmic Solution as Treatmen NCT04704531 | Laboratorios Sophia S.A de C.V. | Phase 2 |
| Unknown | Evaluation of Neovis® Total Multi Versus Systane® Balance on Ocular Dryness Associated With Meibomian Gland Dy NCT05191771 | Horus Pharma | N/A |
| Completed | A Phase 3, Multi-Center Study Evaluating PL9643 in Patients with Dry Eye NCT05201170 | Palatin Technologies, Inc | Phase 3 |
| Completed | Study to Compare the Efficacy of the Ophthalmic Solution Humylub Ofteno® PF With Hyabak® and Lagricel Ofteno® NCT04702776 | Laboratorios Sophia S.A de C.V. | Phase 4 |
| Completed | OC-01 (Varenicline) Nasal Spray and Dry Eye Signs and Symptoms in Daily Disposable Contact Lens Wearers NCT05161208 | Center for Ophthalmic and Vision Research, LLC | Phase 4 |
| Completed | The Effect of 0.05% CsA Eye Drops on Diabetic Patients with Dry Eye Disease NCT06824844 | Peking University Third Hospital | Phase 4 |
| Unknown | Microvascular and Inflammatory Responses of 0.05 Cyclosporine Eye Drop (II) in Treatment of Dry Eye NCT05131152 | Zhongshan Ophthalmic Center, Sun Yat-sen University | N/A |
| Unknown | Meibomian Gland Probing in the Sub-Acute Phase of Patients With Stevens-Johnson Syndrome/Toxic Epidermal Necro NCT05145959 | Massachusetts Eye and Ear Infirmary | N/A |
| Withdrawn | Single Center, Prospective, Randomized, Controlled, Non-significant Risk NCT03286166 | Toyos Clinic | — |
| Completed | A Study to Assess the Efficacy and Safety of Tanfanercept (HL036) Ophthalmic Solution in Participants With Dry NCT05109702 | HanAll BioPharma Co., Ltd. | Phase 3 |
| Completed | Effect of Povidone-iodine 5% Vs 1% on the Ocular Surface in Intravitreal Injections of Anti-VEGF NCT06710951 | José Gerardo García Aguirre | N/A |
| Unknown | Efficacy and Safety of Topical Hydrocortisone on Signs and Symptoms of Dry Eye Associated to Meibomian Gland D NCT05159284 | Laboratorios Thea, Spain | Phase 4 |
| Unknown | Causal Relationship Between Dry Eye and Accommodative Spasm NCT05120401 | Far Eastern Memorial Hospital | — |
| Completed | Optimization of the Ocular Surface Prior to Cataract Surgery Using PROKERA NCT05148507 | Jeff Wongskhaluang | N/A |
| Completed | Strip Meniscometry in Dry Eye Evaluation NCT06120894 | University Hospital Olomouc | — |
| Completed | Evaluate the Safety and Effectiveness of The Tixel Fractional System in the Treatment of Meibomian Gland Disfu NCT04889950 | Novoxel Ltd. | N/A |
| Completed | The Effect of a Novel Blueberry Supplement on Dry Eye Disease NCT05027087 | SightSage Foods and Nutrition Inc. | Phase 3 |
| Completed | An Exploratory Crossover Clinical Trial to Compare the Activity of Reproxalap and Lifitegrast in a Dry Eye Dis NCT05102409 | Aldeyra Therapeutics, Inc. | Phase 2 |
| Completed | Performance and Tolerability of the Medical Device LACRIACT NCT06159569 | Laboratórios Baldacci S.A | N/A |
| Completed | Efficacy of LipiFlow in Patients Affected by Meibomian Gland Dysfunction in Reducing Post-cataract Surgery Dry NCT05062564 | Azienda Ospedaliero-Universitaria Careggi | N/A |
| Unknown | Investigator Initiated Study to Assess the Efficacy of OC-01 (Varenicline) Nasal Spray on Signs and Symptoms o NCT05045508 | Brandon Baartman | Phase 3 |
| Completed | The TRANQUILITY 2 Trial: A Phase 3 Clinical Trial to Assess the Efficacy and Safety in Subjects With Dry Eye D NCT05062330 | Aldeyra Therapeutics, Inc. | Phase 3 |
| Completed | I-DROP MGD Symptomatic Relief and Tear Film Stability NCT05011708 | I-MED Pharma | N/A |
| Completed | Digital Device Users Who Are Treated With Systane Hydration PF NCT04837807 | University of Alabama at Birmingham | Phase 4 |
| Completed | The DEPOT Study (Dry Eye Prescription Options for Therapy) NCT04911361 | Research Insight LLC | Phase 4 |
| Completed | The Effect of Xiidra on Comfort and Dryness in Symptomatic Contact Lens Wearers NCT04297618 | University of Waterloo | Phase 4 |
| Suspended | Neurosensory Abnormalities in SymptomAtic Ocular Surface Patients (NASA) NCT04838223 | Tufts Medical Center | — |
| Completed | Evaluation of Comfort in Subjects With Moderate Dry Eye Disease NCT04830956 | Alcon Research | N/A |
| Completed | Role of Postoperative Lubrication in Cataract Surgery NCT06555224 | Vienna Institute for Research in Ocular Surgery | Phase 4 |
| Completed | CEQUA for Sjogren's Syndrome Dry Eye NCT04835623 | Center for Ophthalmic and Vision Research, LLC | Phase 4 |
| Completed | A Clinical Trial to Assess Subjects With Dry Eye Disease. NCT04971031 | Aldeyra Therapeutics, Inc. | Phase 2 |
| Recruiting | Transcutaneous Auricular Vagus Nerve Stimulation in Dry Eye Disease With Meibomian Gland Dysfunction NCT06544447 | Beijing Tongren Hospital | Phase 1 / Phase 2 |
| Withdrawn | Ocular Inflammation in Cataract Patients and Response to Treatment With Xiidra NCT04120987 | Bucci Laser Vision Institute | Phase 4 |
| Completed | ALY688 Ophthalmic Solution in Subjects With Dry Eye Disease NCT04899518 | Allysta Pharmaceutical | Phase 2 / Phase 3 |
| Completed | Short and Long-term Results of Skin Versus Skin Plus Orbicularis Resection Blepharoplasty NCT05528016 | Marmara University | N/A |
| Completed | Safety And Effectiveness Of The TearCare® System In The Treatment Of The Signs And Symptoms Of Dry Eye Disease NCT04795752 | Sight Sciences, Inc. | N/A |
| Completed | Effect on Ocular Surface Symptoms of Online Education NCT04960696 | Kahramanmaras Sutcu Imam University | — |
| Completed | The Chronology of Lifitegrast Effect on Anterior Surface Rehabilitation (CLEAR) Study NCT04669561 | Research Insight LLC | Phase 4 |
| Terminated | Safety and Efficacy of Dexamethasone Ophthalmic Insert (Dextenza®) in the Management of Clinically Significant NCT04498468 | Johns Hopkins University | Phase 4 |
| Unknown | Effect of Traditional Chinese Medicine on Basic Tear Secretion and Tear Cytokines in Patients With Dry Eye Dis NCT04785261 | China Medical University Hospital | Phase 2 |
| Withdrawn | Effect of Lifitegrast 5% on Tear Film Markers NCT03952481 | Weill Medical College of Cornell University | Phase 4 |
| Unknown | A Study Evaluating HBM9036 Efficacy and Safety on Moderate to Severe Dry Eye NCT04633213 | Harbour BioMed (Guangzhou) Co. Ltd. | Phase 3 |
| Completed | Post-marketing Study Focused on Evaluating I+Med's DayDrop for Improving Signs and Symptoms of Mild/Moderate D NCT06731725 | i+Med S.Coop. | N/A |
| Completed | To Assess the Efficacy and Safety of OTX-DED for the Short-term Treatment of Signs and Symptoms of Dry Eye Dis NCT04747977 | Ocular Therapeutix, Inc. | Phase 2 |
| Completed | Effect of Trigeminal Nerve Stimulation on Corneal Nerves and Chronic Ocular Pain NCT04648085 | Instituto de Oftalmología Fundación Conde de Valenciana | N/A |
| Completed | Detection of Acetylsalicylic Acid and Omega-3 Fatty Acids in Schirmers' Test Strips Using Mass Spectrometry NCT05775536 | Medical University of Vienna | Phase 2 |
| Completed | Acupoint Therapy Device for Dry Eye NCT06720428 | Shanghai 10th People's Hospital | N/A |
| Completed | Evaluation of Ocular Surface in Hemodialysis Patients by Ocular Surface Analyzer NCT04949295 | XiaoYong Liu | — |
| Recruiting | Proteomics Analysis of Human Tears in the Diagnosis and Management of Dry Eye Disease NCT07175909 | The Hong Kong Polytechnic University | N/A |
| Unknown | Dry Eye Management With 3% Diquafosol Before and After Cataract Surgery NCT04952987 | Mun Wai Lee | — |
| Recruiting | Clinical Cohort Study in Patients With Different Subtypes of Primary Sjogren Syndrome Related Dry Eye NCT05605314 | Peking University Third Hospital | — |
| Completed | Study of VVN001 Ophthalmic Solution in Dry Eye Disease NCT04556838 | VivaVision Biotech, Inc | Phase 2 |
| Completed | Clinical Trial to Compare the Safety and Efficacy of Nanodrop® NCT04111965 | Laboratorios Sophia S.A de C.V. | Phase 1 / Phase 2 |
| Unknown | Effect of Artificial Tears on the Parameters of the Eye and Its Impact on IOL Power Calculation for Cataract S NCT04706455 | Second Affiliated Hospital of Xi'an Jiaotong University | N/A |
| Unknown | Wireless Micropump in Dry Eye Patients NCT04667819 | Tianjin Eye Hospital | N/A |
| Completed | The TRANQUILITY Trial: Clinical Trial to Assess the Efficacy and Safety in Subjects With Dry Eye Disease NCT04674358 | Aldeyra Therapeutics, Inc. | Phase 2 / Phase 3 |
| Completed | Assess the Safety and Efficacy of CsA Ophthalmic Gel in Subjects With Moderate to Severe Dry Eye Disease NCT04541888 | Zhaoke (Guangzhou) Ophthalmology Pharmaceutical Ltd. | Phase 3 |
| Unknown | Effects of Topical Insulin on Levels of Tear Inflammatory Mediators NCT04877210 | Universiti Kebangsaan Malaysia Medical Centre | Phase 1 |
| Completed | An Evaluation of the Clinical Utility and Safety of the Visant Medical Canalicular Plug NCT04817085 | Visant Medical, Inc. | N/A |
| Completed | A Study to Assess the Safety and Efficacy of ECF843 vs Vehicle in Subjects With Dry Eye Disease NCT04391894 | Novartis Pharmaceuticals | Phase 2 |
| Completed | Implementation of a Minor Ailment Service in Community Pharmacy Practice NCT05247333 | Universidad de Granada | N/A |
| Completed | Comparing Treatment of Dry Eye With Intracanalicular Dexamethasone, Restasis, and/or Lotemax NCT04555694 | Thomas Chester, OD | Phase 4 |
| Completed | Correlation Study of Corneal Nerve Changes and Dry Eye in Contact Lens Wearers NCT04663529 | Peking University Third Hospital | — |
| Completed | Dry Eye OmniLenz Application of Omnigen Research Study NCT04553432 | Aston University | Phase 4 |
| Completed | Study on Curative Effect and Mechanism of Acupuncture on Neuropathic Pain in Dry Eye Disease NCT04668131 | Peking University Third Hospital | N/A |
| Terminated | Intracanalicular Dexamethasone Insert for the Treatment of Inflammation and Discomfort in Dry Eye Disease (DEc NCT04527887 | Tufts Medical Center | Phase 4 |
| Completed | Safety and Efficacy of Intracanalicular Dexamethasone Compared to Loteprednol Etabonate in Patients With Kerat NCT04418999 | Illinois College of Optometry | EARLY_Phase 1 |
| Completed | Study to Evaluate the Efficacy of SDP-4 in Subjects With Dry Eye Disease (DED) (SDP-4-CS202) NCT04535947 | Silk Technologies, Ltd. | Phase 2 |
| Completed | A Randomized Study of Smile Exercise for Dry Eye NCT04421300 | Zhongshan Ophthalmic Center, Sun Yat-sen University | N/A |
| Unknown | Effect of Re-esterified Triglyceride (rTG) Form Omega-3 Supplements on Dry Eye Following Cataract Surgery NCT04411615 | Samsung Medical Center | N/A |
| Unknown | Epidemiological Study of Dry Eye Disease in Stavanger: Dry Eye Disease in Patients Treated With Intravitreal I NCT04458012 | Helse Stavanger HF | — |
| Unknown | Clinical Outcome of Lipiflow Treatment Prior to Cataract Surgery in Dry Eye Patients NCT04457999 | Samsung Medical Center | N/A |
| Completed | Meibomian Gland Dysfunction Treatment NCT04229888 | Indiana University | N/A |
| Terminated | Evaluation of Tangible Boost for Patients With Stevens Johnson Syndrome, Sjogren's Syndrome, and Graft Vs Host NCT04313725 | Tangible Science | N/A |
| Completed | Lubricating Eye Drops After Routine Cataract Surgery NCT04465071 | Guy's and St Thomas' NHS Foundation Trust | N/A |
| Unknown | Effect of UMSCs Derived Exosomes on Dry Eye in Patients With cGVHD NCT04213248 | Zhongshan Ophthalmic Center, Sun Yat-sen University | Phase 1 / Phase 2 |
| Completed | Efficacy and Safety of Ikervis Under Controlled Environmental Conditions Environment NCT04492878 | Instituto Universitario de Oftalmobiología Aplicada (Institute of Applied Ophthalmobiology) - IOBA | Phase 4 |
| Unknown | Clinical Efficacy of Two Topical Dry Eye Drops for Central Corneal Stain Clearing Over 90 Days NCT04172961 | Toyos Clinic | Phase 4 |
| Terminated | Prospective Study To Assess The Safety And Effectiveness Of Tixel Treatment On Dry Eye Symptoms In Asian Patie NCT04260893 | Novoxel Ltd. | N/A |
| Completed | Lipiflow vs iLux Patient Acceptance and Comfort Study NCT04454983 | Epstein, Arthur B., OD, FAAO | N/A |
| Unknown | Dry Eye Screening and Referral System NCT04413370 | Sun Yat-sen University | — |
| Completed | Phase 3 Study of the Safety and Efficacy of OmegaD Softgels in the Treatment of Dry Eye Disease NCT04181593 | OmegaD LLC | Phase 3 |
| Terminated | Investigating iLux Efficacy in Contact Lens Wearers With Evaporative Dry Eye Disease NCT04159935 | University of Waterloo | Phase 4 |
| Completed | Analysis of the Diagnostic Performance of LacryDiag, a New Analyzer of the Ocular Surface in the Dry Eye NCT04093037 | Centre Hospitalier Universitaire de Saint Etienne | N/A |
| Completed | Evaluating HA 0.15% Compared With Cyclosporine 0.05%, and Efficacy of Combination Therapy in Dry Eye Disease P NCT04127851 | Taejoon Pharmaceutical Co., Ltd. | Phase 4 |
| Completed | Treatment With Allogeneic Adipose-derived Mesenchymal Stem Cells in Patients With Aqueous Deficient Dry Eye Di NCT03878628 | Rigshospitalet, Denmark | EARLY_Phase 1 |
| Unknown | Use of Prophylactic Lubricating Drops After Cataract Surgery NCT04131335 | Guy's and St Thomas' NHS Foundation Trust | N/A |
| Terminated | Predicting the Success of Dry Eye Disease Interventions Using Clinical Tests NCT04125134 | Tufts Medical Center | Phase 4 |
| Completed | Liposomal Sirolimus in Dry Eye Disease NCT04115800 | Instituto de Oftalmología Fundación Conde de Valenciana | EARLY_Phase 1 |
| Unknown | Dry Eye Evaluation System Based on Bioinformatics NCT04109170 | Huaxia Eye Hospital Group | — |
| Completed | Refitting Daily Disposable Contact Lens Wearers With Dry Eye Disease With A Different Daily Disposable Lens Ty NCT04105842 | University of Waterloo | N/A |
| Unknown | Validation of Osmolarity System: Clinical Usability Study NCT03769324 | I-MED Pharma | — |
| Completed | Clinical Trial to Evaluate the Safety and Tolerability of Lagricel® Ofteno Multi-dose Ophthalmic Solution NCT04081610 | Laboratorios Sophia S.A de C.V. | Phase 1 |
| Terminated | Azithromycin for Meibomian Gland Disease NCT03953118 | University of California, San Francisco | Phase 4 |
| Completed | Assessing the Impact of Tixel Treatment of Periorbital Wrinkles on Dry Eye Symptoms and Signs NCT04730336 | Aston University | N/A |
| Completed | Rexon-Eye in Dry Eye NCT04320563 | Singapore National Eye Centre | N/A |
| Completed | A Study to Evaluate the Safety and Effectiveness Assessments of Restylane-Defyne for Punctual Occlusion NCT04022382 | John C Meyer, MD | N/A |
| Recruiting | High Resolution, High-speed Multimodal Ophthalmic Imaging NCT04129021 | Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts | N/A |
| Unknown | Impact of Breathing Exercises and Meditation on Quality of Life in Dry Eye Disease Patients: A Pilot Study NCT03345381 | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | N/A |
| Completed | The Effect of Punctal Plugs on Ocular Surface After Povidone-Iodine Preparation of Intravitreal Injection NCT03945071 | University of Oklahoma | N/A |
| Completed | Comfort Associated With The Use Of Eyelid Cleansing Products Available For The Management Of Demodex Folliculo NCT03987230 | University of Waterloo | N/A |
| Completed | Direct Application of Systane Complete to Contact Lenses NCT03848221 | University of Alabama at Birmingham | Phase 4 |
| Completed | Assessment of the Safety and Efficacy of RGN-259 Ophthalmic Solutions for Dry Eye Syndrome: ARISE-3 NCT03937882 | ReGenTree, LLC | Phase 3 |
| Completed | IVIG-eye Drops Treatment for Dry Eye Disease NCT03992482 | Sandeep Jain, MD | Phase 1 / Phase 2 |
| Completed | A Multi-Center, Randomized, Double-Masked, Parallel-Group, Vehicle-Controlled, Clinical Trial of Reproxalap to NCT03916042 | Aldeyra Therapeutics, Inc. | Phase 2 |
| Unknown | Effect of Preservative-free Low-dose Hyaluronic Acid-containing Salt Solution on Dry Eye Disease NCT03888183 | Chang Gung Memorial Hospital | Phase 4 |
| Completed | The RENEW Trial: A Multi-Center, Randomized, Double-Masked, Parallel-Group, Vehicle-Controlled, Adaptive Phase NCT03879863 | Aldeyra Therapeutics, Inc. | Phase 3 |
| Completed | Study to Evaluate the Safety and Efficacy of SDP-4 in Subjects With Dry Eye Disease (DED) NCT03889886 | Silk Technologies, Ltd. | Phase 2 |
| Completed | Survey: Evaluation of Ocular Surface Disease Symptoms and Patient Satisfaction With Thealoz® Duo After 84 Days NCT04803240 | Laboratoires Thea | — |
| Completed | Tixel Treatment for Dry Eye Symptoms NCT05299619 | Dr Ludger Hanneken | N/A |
| Completed | Tavilermide Ophthalmic Solution for the Treatment of Dry Eye NCT03925727 | Mimetogen Pharmaceuticals USA, Inc. | Phase 3 |
| Completed | A Study Evaluating the Efficacy and Safety on Moderate to Severe Dry Eye NCT04092907 | Harbour BioMed (Guangzhou) Co. Ltd. | Phase 2 |
| Completed | A Study to Assess Efficacy and Safety of HL036 in Subjects With Dry Eyes NCT03846453 | HanAll BioPharma Co., Ltd. | Phase 3 |
| Completed | TearCare System to Treat Dry Eye Disease NCT03857919 | Sight Sciences, Inc. | N/A |
| Unknown | Efficacy and Safety of Hydrolysed Red Ginseng Extract on Dry Eye NCT03992287 | Chonbuk National University Hospital | N/A |
| Completed | Corneal Epithelial Stem Cells and Dry Eye Disease NCT03302273 | Sloan W. Rush, MD | N/A |
| Completed | Clinical Evaluation of Reproducibility of Keratometric Measurements and Influencing Factors in Cataract Patien NCT04196621 | Medical University of Vienna | N/A |
| Withdrawn | Effects of Xiidra on Closed Eye Tear Film Leukocytes in Dry Eye Disease NCT03408015 | University of Alabama at Birmingham | Phase 4 |
| Completed | The Effect Of Lifitegrast On Refractive Accuracy And Symptoms In Dry Eye Patients Undergoing Cataract Surgery NCT03866629 | MDbackline, LLC | — |
| Terminated | MiBo ThermoFlo Lid Temperature Evaluation NCT03787212 | Johnson & Johnson Vision Care, Inc. | N/A |
| Completed | Study of Brimonidine Tartrate Nanoemulsion Eye Drop Solution in the Treatment of Dry Eye Disease (DED) NCT03785340 | Ocugen | Phase 3 |
| Completed | Evaluation of the Performance of MAF-1217 on Cataract Surgery NCT03833908 | VISUfarma SpA | N/A |
| Completed | Evaluation of Systane Complete for the Treatment of Contact Lens Discomfort NCT03682809 | University of Alabama at Birmingham | Phase 4 |
| Withdrawn | Autologous Plasma Treatment for Severe Dry Eye Patients NCT03768115 | Singapore National Eye Centre | EARLY_Phase 1 |
| Completed | Comparing Effect of Topical Tacrolimus 0.03% Versus Cyclosporine 0.05% in Dry Eyes of Secondary Sjogren Syndro NCT03865888 | Pavly Moawd | Phase 3 |
| Unknown | Eyelash Prostheses Compared to 5.0% Lifitegrast BID for Dry Eye Disease. NCT03691636 | D.E.L., LLC | N/A |
| Completed | Efficacy and Safety of Ocudox Lid Wipes Compared to Traditional Lid Cleaning NCT03763006 | Singapore National Eye Centre | Phase 1 |
| Unknown | Efficacy of Two Concentrations of Autologous Serum for the Treatment of Severe Dry Eye NCT03436576 | Pontificia Universidad Catolica de Chile | Phase 3 |
| Completed | A Multicenter Study Evaluating AZR-MD-001 in Patients With Meibomian Gland Dysfunction and Evaporative Dry Eye NCT03652051 | Azura Ophthalmics | Phase 2 |
| Unknown | Evaluation of Efficacy and Safety of Vismed Gel Multi 0.3% Versus Vismed Multi 0.18% on Treatment of Ocular Dr NCT03645850 | Horus Pharma | N/A |
| Completed | Intense Pulse Light Treatment With Meibomian Gland Expression of the Upper Eyelids in Dry Eye Disease NCT03658811 | Toyos Clinic | N/A |