Clinical Trials Directory

Trials / Recruiting

RecruitingNCT06830551

The Effect of Cord Blood Serum Eyes Drops Administer in Patients With Severe Keratopathy Related to EGFR-I Treatment

Personalized Approach in the Treatment of Patients Affected by Severe Dry Eye Associated With Therapy With EGFR Inhibitors (EGRFR-I) With Growth Factors in Cord Blood Serum (CBS) Eye Drops

Status
Recruiting
Phase
N/A
Study type
Interventional
Enrollment
10 (estimated)
Sponsor
IRCCS Azienda Ospedaliero-Universitaria di Bologna · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The study aim to evaluate the efficacy of cord blood eye drops in the healing of the damaged corneal epithelium.

Detailed description

Patients undergoing treatment with EGFR inhibitor for lung cancer might develop corneal damage. The study aims to evaluate the healing of corneal epithelium by administering cord blood eye drops for one month.

Conditions

Interventions

TypeNameDescription
DRUGadministration cord blood based eye drops, standardized to the deliver BDNF.administration cord blood based eye drops customized to deliver epitelio tropic factors, incluiding EGF in EGFR blocked cells

Timeline

Start date
2023-09-12
Primary completion
2025-12-31
Completion
2025-12-31
First posted
2025-02-17
Last updated
2025-02-17

Locations

1 site across 1 country: Italy

Source: ClinicalTrials.gov record NCT06830551. Inclusion in this directory is not an endorsement.