NCT07323264

SAS 1: Develop Ocular Disease (OSD) Diagnostic, Algorithms, and Management Protocols for Cataract Surgery

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 110 (estimated)
• Sponsor: Louis Tong · Other Government
• Sex: All
• Age: 21 Years – 99 Years
• Healthy volunteers: Accepted

Summary

Patient: Tear film issues resulting in poor visual outcomes are a major cause of dissatisfaction after cataract surgery. There is no universal best preoperative algorithm for managing the ocular surface prior to surgery. Industry: Recent advances in tear/cornea imaging and refractive cataract surgery such as multifocal intraocular lenses will be advantageous to patients only if tear film issues can be addressed. Society: Cataract surgery is the most common ophthalmic surgery done in Singapore and worldwide. Improving vision by attending to tear film problems improves quality of life.

Detailed description

Phase 1: Investigate the impact of ocular surface disease (OSD) on post-operative outcomes in cataract surgery. Phase 1A: Longitudinal interventional parallel group study; small cohort to determine the impact of moderate dry eye for at-risk patient groups. Phase 1B: Longitudinal interventional parallel group study; larger cohort of to compare outcomes based on different IOL types.

Conditions

• Dry Eye

Timeline

• Start date: 2025-06-27
• Primary completion: 2027-06-30
• Completion: 2027-10-31
• First posted: 2026-01-07
• Last updated: 2026-01-07

Locations

1 site across 1 country: Singapore