Trials / Completed
CompletedNCT04949295
Evaluation of Ocular Surface in Hemodialysis Patients by Ocular Surface Analyzer
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 36 (actual)
- Sponsor
- XiaoYong Liu · Academic / Other
- Sex
- All
- Age
- 25 Years – 72 Years
- Healthy volunteers
- Accepted
Summary
We clinically observed that some hemodialysis patients had corneal epithelial dryness, shedding, edema, and persistent epithelial nonunion after ocular surgery, which seriously affected the effect of surgery, and it is necessary to study the ocular surface characteristics of hemodialysis patients. In this study, we examined the ocular surface and analyzed and investigated the characteristics of the ocular surface in hemodialysis patients to provide a basis for ocular surface intervention or treatment in hemodialysis patients before ocular surgery in clinical practice.
Detailed description
This study is a clinical case-control study. A total of 36 hemodialysis patients and 36 normal subjects were randomly selected from the Nephrology Department of the First Affiliated Hospital of Jinan University .All the subjects in the hemodialysis group (n = 36, 72 eyes) and the normal group (n = 36, 72 eyes) were investigated with the OSDI scale, and then bilateral ocular surface examinations were performed with Keratograph5M eye surface comprehensive analyzer. Non-invasive tear meniscus height (NITMH), first tear film break-up time (FTBUT), average tear film break-up time (ATBUT), dry eye severity grade, tear film lipid layer analysis (distribution and color), tear film lipid layer thickness grade, meibomian gland opening blocking site, meibomian gland opening blocking analysis, meibomian gland opening secretion oil character score, eye redness index analysis (conjunctiva, ciliary shape), and meibomian gland absence area score were recorded.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DEVICE | ocular surface analyzer | Using ocular surface analyzer for Inspection |
Timeline
- Start date
- 2021-01-01
- Primary completion
- 2021-12-31
- Completion
- 2021-12-31
- First posted
- 2021-07-02
- Last updated
- 2022-04-19
Locations
1 site across 1 country: China
Source: ClinicalTrials.gov record NCT04949295. Inclusion in this directory is not an endorsement.