Clinical Trials Directory

Trials / Sponsors / Zhongnan Hospital

Zhongnan Hospital

Academic / Other · 95 registered clinical trials28 currently recruiting.

StatusTrialPhaseStarted
Not Yet RecruitingFULIRI Plus Targeted Therapy for First-line Conversion Therapy of Colorectal Cancer Liver Metastases.
Colo-rectal Cancer
Phase 22026-06-01
Not Yet RecruitingAn Open-label, Single-arm, Single-center Study to Evaluate the Diagnostic Efficacy of a Novel PET Probe, 68Ga-
Neoplasms
EARLY_Phase 12026-03-10
RecruitingEfficacy and Safety of Intrapulmonary Percussive Ventilation in Patients With Pulmonary Infection Receiving In
Pneumonia
N/A2026-03-06
Not Yet RecruitingA Phase II Study of Utidelone With Toripalimab in Advanced Cervical Cancer
Cervical Cancer, Recurrent, Metastatic
Phase 22026-02-01
RecruitingA Study on the Effect of Medical Students' Literature Reading Patterns on Cognitive Load and Academic Writing
Accuracy in Understanding the Core Content of English Medical Literature
2026-01-20
Not Yet RecruitingEvaluation of the Diagnostic Efficacy of a αvβ6/FAP-Targeting Heterodimeric Probe in Patients With Malignant S
PET / CT, Solid Tumors, Adult
2026-01-15
Not Yet RecruitingRadiotherapy Plus CAPOX, and Iparomlimab and Tuvonralimab (QL1706) as Neoadjuvant Therapy for LARC
Rectal Cancer Patients
Phase 22026-01-01
Not Yet RecruitingStudy on the Efficacy of Temporal Interference Stimulation (TIS) for Parkinson's Disease
Temporal Interference Stimulation (TIS), Parkinson's Disease
N/A2025-12-30
RecruitingRandomised Controlled Trial of Artificial Intelligence-assisted Health Education
Leukaemia, Multiple Myeloma (MM), Lymphoma, Large B-Cell, Diffuse (DLBCL), Lymphoma, Lymphoma
N/A2025-06-28
Not Yet RecruitingGranzyme B-targeted PET Imaging Monitoring Tumor Responses to Immunotherapy
PET/CT, Solid Tumors, Adult, Solid Tumors, Advanced Solid Tumors
2025-04-01
RecruitingHigh - Dose Vitamin C Infusion Regimen Based on Pharmacokinetic Characteristics for Patients With Advanced Mal
Vitamin C
Phase 12025-03-30
RecruitingEffect of Adding Electroacupuncture to Anti-cancer Therapy-induced Peripheral Neuropathy
Chemotherapy-induced Peripheral Neuropathy (CIPN), Cancer
N/A2025-03-20
Not Yet RecruitingThe Accuracy of Targeted Lymph Node Dissection of Non-small Cell Lung Cancer Patients According to Predictive
Non-small Cell Lung Cancer
N/A2025-01-01
Active Not RecruitingMinimally Invasive Suprachoroidal Drainage for the Treatment of Neovascular Glaucoma
Neovascular Glaucoma
N/A2025-01-01
RecruitingSafety and Efficacy of NRG-103 Injection in the Treatment of Recurrent Glioblastoma Patients
Glioblastoma (GBM)
EARLY_Phase 12024-12-19
RecruitingClinical Study on the Immune Response Characteristics of Novel Coronavirus and Influenza Virus Infection
COVID-19, Influenza
2024-09-19
Enrolling By InvitationRadiotherapy with Immunotherapy and Anti-Angiogenic Therapy for Advanced HER2-Negative Breast Cancer: a Single
Breast Cancer, Metastatic Breast Cancer
Phase 1 / Phase 22024-08-08
Not Yet RecruitingEfficacy of Semi-rigid Ureteroscopic Laser Lithotripsy in the Treatment of Proximal Ureteral Stones: a Randomi
Urolithiasis, Proximal Ureteral Stone
N/A2024-06-26
Not Yet RecruitingTislelizumab in Combination With Chemotherapy as a Neoadjuvant Treatment for Advanced Endometrial Cancer
Endometrial Neoplasms
N/A2024-06-01
UnknownDocetaxel Alone or in Combination With Enzalutamide for mCRPC Previously Treated With Abiraterone at mHSPC Sta
Prostate Cancer, Castrate Resistant Prostate Cancer
Phase 2 / Phase 32024-06-01
CompletedClinical Features and Visual Prognosis of Infectious Endophthalmitis
Endophthalmitis
2024-06-01
Active Not RecruitingA Clinical Trial Comparing Staged Turnbull-Cutait Pull-through Anastomosis With Direct Anastomosis Plus Prophy
Rectal Cancer, Rectal Carcinoma
N/A2024-05-08
WithdrawnDetection of G-quadruplex DNA Methylation in Cancer
Cancer, DNA G-quadruplex, Methylation
2024-04-30
CompletedHealing of Corneal Incision After Cataract Surgery in Diabetic Patients
Diabetes, Cataract
2024-04-01
UnknownThe Value of Peripheral Blood CD34+ Cell Dynamics Monitoring in Autologous Hematopoietic Stem Cell Transplant
Granulocyte Colony-Stimulating Factor
EARLY_Phase 12024-02-01
UnknownPET-CT Imaging Features of Meibomian Glands
MGD-Meibomian Gland Dysfunction, Positron-Emission Tomography, Dry Eye
2024-01-31
RecruitingMA+AZA Regimen for the Treatment of Newly Diagnosed Acute Myeloid Leukemia (AML)
Acute Myeloid Leukaemia
Phase 32024-01-18
Active Not RecruitingMechanism of Nitric Oxide on Ventilator-induced Diaphragm Dysfunction with Extracorporeal Membrane Lung Assist
Tracheal Intubation, Extracorporeal Membrane Oxygenation, Nitric Oxide
2024-01-16
Active Not RecruitingA Cross-sectional Study of Ocular Manifestations During the Covid-19 Pandemic in Hubei Province
COVID-19, Ocular Surface Disease
2024-01-01
UnknownCisplatin Plus Temozolomide Compared With Temozolomide in Patients With MGMT Promotor Unmethylated Glioblastom
Glioblastoma Multiforme of Brain
Phase 1 / Phase 22024-01-01
UnknownAnalysis of Ocular Complications of AIDS Patients in Ophthalmic Consultation
Ocular Complications in AIDS Patients, Such as Fundus Opportunistic Infections, Microangiopathy, and Uveitis
2023-10-01
UnknownStudy on the Pathogenesis of Retinal Vascular Diseases Based on Body Fluid Metabolomics
Metabolomics; Retinopathy; Etiology
2023-09-07
RecruitingEffects of Acupoint Massage Around Eyes on Ocular Biological Indexes
Investigating the Effects of Periocular Acupressure on Ocular Biological Indicators
N/A2023-09-01
CompletedResearch on the Accurate Diagnosis of Urinary Tract Tumors and the Development of Kits
Bladder Cancer, Urothelial Carcinoma
2023-06-01
UnknownA Clinical Trial on Booster Immunization of Two COVID-19 Vaccines Constructed From Different Technical Routes
COVID-19
N/A2023-05-30
UnknownCXCR4 Targeted PET Imaging in APA Preoperative Localization Diagnosis
Aldosterone-Producing Adenoma
N/A2023-05-30
CompletedFluorescence Imaging With Indocyanine Green(ICG) in Endoscopic Spinal Surgery
Disc Herniation
Phase 1 / Phase 22023-04-11
UnknownFunction and Morphological Characteristics of Meibomian Gland in Patients With Renal Anemia
Dry Eye, MGD-Meibomian Gland Dysfunction
N/A2023-04-01
CompletedA Modified Calculation Formula for Meibomian Gland Grading
Meibomian Gland Dysfunction
2023-04-01
RecruitingCadonilimab Plus Anlotinib for R/M/P Cervical Cancer
Cervical Cancer
Phase 22023-02-16
UnknownShen Hai Long Capsule for Male Asthenospermia
Efficacy and Safety of Shen Hai Long Capsule for Mild to Moderate Asthenospermia in Men
N/A2023-02-15
UnknownA Study of Shengxuening Tablet in the Treatment of Chemotherapy-related Anemia in Hematologic Tumors
Hematological Malignancy, Cancer-Related Anemia
Phase 32023-02-07
UnknownEtoposide Plus Cisplatin Compared With Temozolomide in Patients With Glioblastoma
MGMT-Unmethylated Glioblastoma
Phase 22023-02-01
UnknownApplication of Point-of-care Ultrasound in Rapid Assessment of Cardiac Arrest Patients
Cardiac Arrest, Point-of-care Ultrasound, Cardiopulmonary Resuscitation
2023-02-01
UnknownClinical Study for Combined Analysis of CTC and Exosomes on Predicting the Efficacy of Immunotherapy in Patien
Hepatocellular Carcinoma
2023-01-01
RecruitingIntegrin αvβ6-targeted PET in Malignant Tumors
Malignant Neoplasm, PET/CT, Non-Small Cell Lung Cancer
2023-01-01
Active Not RecruitingDisitamab Vedotin Combined With Fruquintinib for mCRC With HER2 Expression
HER2, Colorectal Cancer
Phase 42023-01-01
RecruitingThe Effect of Eyeliner on Tear Composition, Tear Secretion and Tear Film Stability.
Dry Eye
2022-11-20
UnknownFirst-in-human (FIH) Phase I Trial of BS-006 in Cervical Cancer
Uterine Cervical Neoplasms
Phase 12022-09-16
UnknownSafety and Efficacy of a New Approach to Delineating Clinical Target Volume of Glioblastoma
Glioblastoma
N/A2022-09-01
UnknownThe Safety and Immunogenicity of SARS-CoV-2 mRNA Vaccine (SYS6006) as Heterologous Booster in Participants Age
SARS-CoV-2, Safety, Immunotoxicity
N/A2022-08-13
UnknownAn Open, Single Center, Randomized Controlled Clinical Study of UCB (Cord Blood) in the Treatment of Newly Dia
UCB (Cord Blood) Microtransplantation in the Treatment of Newly Diagnosed Acute Myeloid Leukemia (AML)
Phase 12022-08-10
UnknownA Comparative Study on the Efficacy of AI Temperature-controlled Radiofrequency Technology and Electrical Stim
Vulvar Lichen Sclerosus
N/A2022-07-07
UnknownFibroblast Activation Protein Inhibitor PET/CT Imaging in Malignant Tumor of Digestive System
Gastrointestinal Cancer
2022-06-23
RecruitingInfusion Set Replacement Intervals for Critically Ill Patients
Critical Illness
N/A2022-05-15
UnknownThe Usefulness of CaIMR in Patients With STEMI
CaIMR, Prognosis, ST-segment Elevation Myocardial Infarction
2022-05-15
UnknownSurufatinib Alone or Combined With Anti-PD-1 mAb in the Treatment of Advanced Hepatocellular Carcinoma
Hepatocellular Carcinoma; Targeted Therapy; Progression-free Survival
Phase 22022-04-16
CompletedUrine Interleukin-37 as a Biomarker of Mortality Risk in Patients With Sepsis
Sepsis
2022-03-23
RecruitingCXCR4-targeted PET/CT Imaging in Hematological Malignancies
CXCR4, PET/CT, Hematological Malignancy
N/A2022-03-01
UnknownMulti-mode Rehabilitation of Abdominal Tumor Patients Undergoing Concurrent Chemoradiotherapy
Concurrent Chemoradiotherapy;Nutrition;Multimodal Rehabilitation
Phase 22022-02-07
UnknownNoninvasive and Dynamic Monitoring the Biological Parameters of Eyes in Different Age Groups
Myopia
2022-02-01
UnknownThe Function of PET Molecular Imaging Targeting Fibroblast Activation Protein in the Hepatobiliary Malignancie
Hepatobiliary Diseases
2022-01-20
UnknownThe Neuro-epigenetics Biomarkers of Postoperative Delirium in Elderly Patients Undergoing Hip/Knee Replacement
Postoperative Delirium
2021-11-03
CompletedDesflurane and Postoperative Sleep Quality in Patients Undergoing Elective Breast Surgery
Desflurane, Propofol, Postoperative Sleep
N/A2021-10-21
RecruitingExploring the Application Value of PET Molecular Imaging Targeting FAP in Oral Squamous Cell Carcinoma
PET/CT, FAPI, Oral Cancer
2021-09-15
RecruitingCervical Cancer Screening with NGS-HPV Technology Based on Menstrual Blood
Cervical Cancer
2021-09-01
UnknownEffect of Es-ketamine on Postoperative Delirium Among Old Patients With Lobectomy
Postoperative Delirium
N/A2021-07-31
UnknownEffect of Radiotherapy Concurrent of TTFields in Patients With Glioblastoma
Glioma, Glioblastoma
N/A2021-06-19
UnknownSafety and Efficacy of Esmketamine Versus Dexmedetomidine
Osa Syndrome
Phase 42021-05-01
UnknownConcurrent Radiochemotherapy Plus Anlotinib for Locally Advanced Cervical Cancer
Uterine Cervical Neoplasms, Chemoradiotherapy, Angiogenesis
N/A2021-03-12
Recruiting68Ga-FAPI PET/CT in Malignant Tumors
Fibroblast Activation Protein Inhibitor, PET/CT, Malignant Neoplasm
N/A2021-02-23
UnknownClinical Study of MAK Immune Cells in the Treatment of PHC
Primary Hepatocellular Carcinoma
N/A2021-01-01
UnknownA Pharmacokinetics Study of Daptomycin in Critically Ill Patients and Effects of Daptomycin on Kidney
Outcome, Fatal, Infection
2020-12-01
CompletedTrained Immunity in Fungal Infection and Its Mechanism
BCG Vaccination
EARLY_Phase 12020-09-01
UnknownCompletely Abdominal Approach Laparoscopic Partial Intersphincteric Resection for Rectal Cancer
Rectal Cancer
N/A2020-07-19
UnknownHigh Dose Vitamin C Combined With Metformin in the Treatment of Malignant Tumors
Hepatocellular Cancer, Pancreatic Cancer, Gastric Cancer
Phase 22020-07-01
UnknownBicarbonated Ringer's Solution Versus Lactated Ringer's Solution in Patients With Septic Shock
Septic Shock, Fluid Resuscitation, Crystalloid Solution
N/A2020-07-01
UnknownStudy on Early Brain Injury Mechanism and Comprehensive Intervention of VCI
Vascular Cognitive Impairment
N/A2020-07-01
UnknownEffects of Metabolic Enzymes and Transporter Gene Polymorphisms on the Pharmacokinetics and Metabolism of Oral
Abiraterone Acetate, Gene Polymorphism, Pharmacokinetic
EARLY_Phase 12020-05-05
CompletedAutoimmunity Contributes to the Severe Progression of COVID-19
Coronavirus Disease 2019
2020-03-10
UnknownCirculating Tumor Cell Capture for Early Diagnosis and Postoperative Tumor Recurrence Monitoring of Liver Canc
Circulating Tumor Cell
2020-01-22
UnknownBortezomib Combined With DAG Regimen in the Treatment of Refractory/Relapsed AML
Bortezomib, Acute Myeloid Leukemia
Phase 12020-01-01
CompletedPlasma-free Replacement in Patients With Multiple Myeloma
Multiple Myeloma
N/A2020-01-01
CompletedClinical Study of hUC-MSCs Treating Decompensated Liver Cirrhosis With HBV
HBV
EARLY_Phase 12019-09-08
CompletedProtein Kinase N1 Level in Patients Undergoing Cardiac Surgery
Acute Kidney Injury, Extracorporeal Circulation; Complications, Surgery
2019-07-22
UnknownMultiple Biomarkers in ICU Sepsis Patients
Sepsis, Severe, Sepsis, Septic Shock
2018-12-30
CompletedClinical Characteristics of Neovascular Glaucoma
Neovascular Glaucoma
2018-01-01
CompletedRetrospective Analysis of the Clinical Characteristics of Retinal Vein Occlusion
Retinal Vein Occlusion
2018-01-01
UnknownCytoreductive Surgery(CRS) Plus Hyperthermic Intraperitoneal Chemotherapy(HIPEC) With Lobaplatin in Advanced a
Ovarian Cancer, Ovary Neoplasm, Ovarian Neoplasms
Phase 32017-09-30
UnknownAdjuvant IMRT With Concommitant Raltitrexed Chemotherapy for Locally Advanced Gastric Cancer After D0/D1 Radic
Gastric Cancer
Phase 22017-01-01
UnknownEffect of FDG-PET/CT for Simulation and Radiation Treatment Planning in Oral Cancer Patients
Oral Cancer, Radiotherapy; Complications
Phase 22017-01-01
CompletedSVF Therapy for Human Knee Osteoarthritis
Knee Osteoarthritis
N/A2016-12-19
CompletedAberrant Myeloid Lineage Differentiation in HIV/AIDS Patients
HIV Infections, Leukemia
2016-01-01
UnknownComparing Preoperative Short-course Radiotherapy With or Without Local Boost for Rectal Cancer
Rectal Cancer
N/A2015-07-01
CompletedStudy of Postoperative Delirium in Elderly People After Orthopedic Surgery
Postoperative Delirium
2015-03-01