NCT07312279

Study on the Efficacy of Temporal Interference Stimulation (TIS) for Parkinson's Disease

• Status: Not Yet Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 24 (estimated)
• Sponsor: Zhongnan Hospital · Academic / Other
• Sex: All
• Age: 40 Years
• Healthy volunteers: Not accepted

Summary

The primary objective of this clinical study is to evaluate the therapeutic efficacy of Temporal Interference Stimulation (TIS), a non-invasive deep brain stimulation technique, in patients with Parkinson's disease, and to further investigate its potential mechanisms of action. Although TIS offers lower stimulation intensity and precision compared to conventional Deep Brain Stimulation (DBS), it possesses the distinct advantage of being non-invasive. This study utilizes TIS to explore different stimulation targets analogous to those used in DBS for Parkinson's disease, thereby providing valuable insights for subsequent DBS surgical interventions. The findings will contribute preliminary exploratory evidence regarding the application of non-invasive deep brain stimulation technology in the treatment of Parkinson's disease.

Conditions

• Temporal Interference Stimulation (TIS)
• Parkinson's Disease

Interventions

Type	Name	Description
DEVICE	TIS	Temporal Interference Stimulation

Timeline

• Start date: 2025-12-30
• Primary completion: 2026-05-31
• Completion: 2026-12-31
• First posted: 2025-12-31
• Last updated: 2025-12-31