NCT06287879

Function and Morphological Characteristics of Meibomian Gland in Patients With Renal Anemia

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 50 (estimated)
• Sponsor: Zhongnan Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

Renal anemia refers to anemia in which the absolute or relative production of erythropoietin (EPO) is insufficient due to various kidney diseases, and uremic toxins affect erythropoietin production and its lifespan. Common treatment drugs for renal anemia include erythropoietin EPO and Roxadustat (FG-4592). Medical history information was collected from patients with renal anemia who visited the ophthalmology department with dry eye symptoms. This study will help to determine the function and morphological characteristics of meibomian gland in patients with renal anemia

Detailed description

1. Collect medical records of patients with renal anemia who visited the ophthalmology outpatient department of Zhongnan Hospital and hospitalized patients with renal anemia 2. Patients were divided into Rosallistat group, and EPO group according to their drug use history. 3. The dry eye analysis results of all patients were collected, and the lacrimal river height, tear film rupture time and meibomian gland grade were counted. The results of dry eye examination were analyzed statistically. 4. Complete data collection, conduct statistical analysis, and evaluate the analysis results.

Conditions

• Dry Eye
• MGD-Meibomian Gland Dysfunction

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Dry eye examination	1. Lacrimal river height 2. tear break-up time 3. tear-film lipid layer thickness 4. meibomian glands two-dimensional digital infrared images

Timeline

• Start date: 2023-04-01
• Primary completion: 2024-12-20
• Completion: 2024-12-30
• First posted: 2024-03-01
• Last updated: 2024-03-01

Locations

1 site across 1 country: China