Clinical Trials Directory

Trials / Completed

CompletedNCT04674358

The TRANQUILITY Trial: Clinical Trial to Assess the Efficacy and Safety in Subjects With Dry Eye Disease

The TRANQUILITY Trial: Multi-Center Randomized, Double-Masked, Parallel Design, Vehicle-Controlled Phase 2/3 Clinical Trial to Assess the Efficacy and Safety of 0.25% Reproxalap Ophthalmic Solution Compared to Vehicle in Subjects With Dry Eye Disease

Status
Completed
Phase
Phase 2 / Phase 3
Study type
Interventional
Enrollment
329 (actual)
Sponsor
Aldeyra Therapeutics, Inc. · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The TRANQUILITY Trial: Multi-Center Randomized, Double-Masked, Parallel Design, Vehicle-Controlled Phase 2/3 Clinical Trial to Assess the Efficacy and Safety of 0.25% Reproxalap Ophthalmic Solution Compared to Vehicle in Subjects with Dry Eye Disease.

Conditions

Interventions

TypeNameDescription
DRUGReproxalap Ophthalmic Solution (0.25%)Reproxalap Ophthalmic Solution (0.25%) administered over two consecutive days (Day one pre-dry eye chamber and Day two dry eye chamber assessment).
DRUGVehicle Opthalmic SolutionVehicle Ophthalmic Solution administered over two consecutive days (Day one pre-dry eye chamber and Day two dry eye chamber assessment).

Timeline

Start date
2020-11-21
Primary completion
2021-09-12
Completion
2021-09-12
First posted
2020-12-19
Last updated
2025-03-19
Results posted
2025-03-19

Locations

1 site across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT04674358. Inclusion in this directory is not an endorsement.