| Not Yet Recruiting | Study to Evaluate Long-Term Safety of Intravitreal OTX-TKI (Axitinib Implant) in Participants With Neovascular Neovascular Age-Related Macular Degeneration (nAMD) | Phase 3 | 2026-04-01 |
| Recruiting | A Study to Evaluate the Efficacy and Safety of OTX-TKI (Axitinib Implant) in Participants With Non-Proliferati Non-Proliferative Diabetic Retinopathy | Phase 3 | 2025-11-17 |
| Active Not Recruiting | Study to Evaluate the Efficacy and Safety of Intravitreal OTX-TKI (Axitinib Implant) in Subjects With Neovascu Neovascular Age-related Macular Degeneration | Phase 3 | 2024-11-27 |
| Active Not Recruiting | Study to Evaluate the Efficacy and Safety of Intravitreal OTX-TKI (Ocular Therapeutix) (Axitinib Implant) in S Neovascular Age-Related Macular Degeneration | Phase 3 | 2024-01-29 |
| Completed | OTX-DED for the Short-term Treatment of the Symptoms of Dry Eye Disease (DED) Dry Eye Syndromes, Eye Diseases | Phase 2 | 2023-05-11 |
| Unknown | Study to Evaluate the Safety, Tolerability, and Efficacy of OTX-TKI in Subjects With Moderately Severe to Seve Non-proliferative Diabetic Retinopathy | Phase 1 | 2023-01-15 |
| Unknown | An Observational, Qualitative Study Assessing Eye Drop Administration Ocular Injury | — | 2022-04-21 |
| Completed | A Study to Evaluate the Efficacy and Safety of OTX-TIC (Travoprost) Intracameral Implant for Patients With Ope Open Angle Glaucoma, Ocular Hypertension | Phase 2 | 2022-03-16 |
| Completed | Study Evaluating the Treatment of OTX-TKI for Subjects With Neovascular Age-related Macular Degeneration Neovascular Age-Related Macular Degeneration | Phase 1 | 2021-07-28 |
| Terminated | A Human Factors Study to Evaluate a Novel Intracanalicular Insertion Device in Healthy Subjects Healthy | EARLY_Phase 1 | 2021-06-01 |
| Completed | To Assess the Efficacy and Safety of OTX-DED for the Short-term Treatment of Signs and Symptoms of Dry Eye Dis Dry Eye | Phase 2 | 2021-02-12 |
| Completed | A Study Assessing the Safety and Efficacy of Dextenza® for the Treatment of Ocular Pain and Inflammation Follo Cataract | Phase 3 | 2020-09-04 |
| Completed | Study to Evaluate the Safety, Tolerability, and Efficacy of OTX-CSI in Subjects With Dry Eye Disease. Dry Eye Disease | Phase 1 / Phase 2 | 2020-04-23 |
| Completed | A Study Evaluating the Safety and Efficacy of OTX-DP for the Treatment of Allergic Conjunctivitis Allergic Conjunctivitis | Phase 3 | 2019-08-05 |
| Completed | CLN-0046: Treatment of AMD Subjects With OTX-TKI Neovascular Age-related Macular Degeneration | Phase 1 | 2019-02-18 |
| Completed | A Study to Evaluate the Long Term Safety of OTX-TP (Sustained Release Travoprost) Intracanalicular Insert Open Angle Glaucoma and Ocular Hypertension | Phase 3 | 2018-07-10 |
| Completed | CLN-0045: Safety, and Efficacy of OTX-TIC in Participants With Open Angle Glaucoma or Ocular Hypertension Ocular Hypertension, Open Angle Glaucoma | Phase 1 | 2018-04-25 |
| Completed | Phase 3 Study Evaluating Safety and Efficacy of OTX-TP in Subjects With OAG or OHT Open Angle Glaucoma, Ocular Hypertension | Phase 3 | 2016-11-07 |
| Completed | OTX-15:003: A Phase 3 Study Evaluating the Safety and Efficacy of OTX-DP for the Treatment of Ocular Inflammat Post-Surgical Ocular Pain, Post-Surgical Ocular Inflammation | Phase 3 | 2015-10-01 |
| Completed | OTX-15-002: A Phase 3 Study Evaluating the Safety and Efficacy of OTX-DP for the Treatment of Chronic Allergic Chronic Allergic Conjunctivitis | Phase 3 | 2015-06-01 |
| Completed | OTX-14-007: A Phase 3 Study Evaluating the Safety and Efficacy of OTX-DP for the Treatment of Chronic Allergic Chronic Allergic Conjunctivitis | Phase 3 | 2015-04-01 |
| Completed | OTX-14-006: A Phase 2 Study Evaluating the Safety and Efficacy of OTX-DP for the Treatment of Dry Eye Dry Eye | Phase 2 | 2015-01-01 |
| Completed | ReSure Sealant Post Approval Study Adverse Events | — | 2014-12-01 |
| Completed | Phase 2b Study Evaluating Safety and Efficacy of OTX-TP Compared to Timolol Drops in the Treatment of Subjects Glaucoma, Ocular Hypertension | Phase 2 | 2014-11-01 |
| Completed | OTX-14-003: A Phase 3 Study Evaluating the Safety and Efficacy of OTX-DP for the Treatment of Ocular Inflammat Post-Surgical Ocular Pain, Post-Surgical Ocular Inflammation | Phase 3 | 2014-04-01 |
| Completed | OTX-14-001: A Phase 2 Study Evaluating the Safety and Efficacy of OTX-DP for the Treatment of Chronic Allergic Chronic Allergic Conjunctivitis | Phase 2 | 2014-03-01 |
| Completed | Phase 3 Study Evaluating Safety and Efficacy of OTX-DP for Treatment of Ocular Inflammation and Pain After Cat Post Ocular Surgical Inflammation and Pain | Phase 3 | 2014-02-01 |
| Completed | Multi-Arm Feasibility Study Evaluating OTX-TP Compared to Timolol in Treatment of Subjects With Open Angle Gla Glaucoma | Phase 1 | 2013-04-01 |
| Unknown | Non-Significant Risk Feasibility Study to Assess Retention and Replacement of the OTX Punctum Plug Healthy Subjects | Phase 1 | 2013-02-01 |
| Completed | Phase II Study Evaluating Safety/Efficacy of OTX-DP for Treatment of Ocular Inflammation and Pain After Catara Ocular Inflammation and Pain | Phase 2 | 2012-10-01 |
| Completed | ReSure Sealant Pivotal Study Cataract Surgery Incision Leak | Phase 3 | 2011-12-01 |
| Completed | I-ZIP Ocular Bandage Pivotal Study Cataract | N/A | 2008-10-01 |
| Withdrawn | OTX-14-002: Device Exposure Registry Endophthalmitis | — | — |