Clinical Trials Directory

Trials / Completed

CompletedNCT01666210

Phase II Study Evaluating Safety/Efficacy of OTX-DP for Treatment of Ocular Inflammation and Pain After Cataract Surgery

A Prospective, Multicenter, Randomized, Parallel-Arm, Double-Masked, Vehicle Controlled Phase II Study Evaluating the Safety and Efficacy of OTX-DP for the Treatment of Ocular Inflammation and Pain After Cataract Surgery

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
60 (actual)
Sponsor
Ocular Therapeutix, Inc. · Industry
Sex
All
Age
21 Years
Healthy volunteers
Not accepted

Summary

To evaluate the safety and efficacy of OTX-DP as a sustained release drug (dexamethasone) depot when placed in the canaliculus of the eyelid for the treatment of ocular inflammation and pain in subjects who have undergone cataract extraction with intra-ocular lens implantation.

Conditions

Interventions

TypeNameDescription
DRUGOTX-DP (Dexamethasone punctum plug)Sustained and tapered release of dexamethasone from hydrogel punctum plug
DRUGPlacebo Vehicle Punctum PlugHydrogel punctum plug without dexamethasone

Timeline

Start date
2012-10-01
Primary completion
2013-08-01
Completion
2013-08-01
First posted
2012-08-16
Last updated
2021-10-19
Results posted
2017-04-27

Locations

1 site across 1 country: United States

Source: ClinicalTrials.gov record NCT01666210. Inclusion in this directory is not an endorsement.