| Not Yet Recruiting | An Exploratory Study of the Efficacy and Safety of Esketamine and Dexmedetomidine in Non-Intubated ICU Patient NCT07377981 | The First Affiliated Hospital with Nanjing Medical University | Phase 4 |
| Recruiting | Intranasal Dexmedetomidine-esketamine Administration and Postoperative Pain in Pediatric Patients NCT07479602 | Peking University First Hospital | Phase 4 |
| Not Yet Recruiting | Dexmedetomidine-esketamine Combination and Chronic Postsurgical Pain After Spinal Surgery NCT07525999 | Peking University First Hospital | Phase 4 |
| Not Yet Recruiting | Dexmedetomidine-esketamine Combination and Moderate-to-severe Pain After Spinal Surgery NCT07523321 | Peking University First Hospital | Phase 4 |
| Recruiting | Comparison of Post Operative Analgesia in Patients Undergoing Lower Abdominal Surgeries Receiving Ultrasound G NCT07508202 | Pakistan Institute of Medical Sciences | Phase 4 |
| Recruiting | Effect of Intranasal Dexmedetomidine on the Incidence of Emergence Agitation in Children Undergoing Strabismus NCT07523438 | Alexandria University | N/A |
| Not Yet Recruiting | Propofol-Only Versus Dexmedetomidine-Propofol in Children Undergoing Magnetic Resonance Imaging NCT07369128 | Boston Children's Hospital | Phase 4 |
| Recruiting | Virtual Reality Versus Intravenous Dexmedetomidine on Maternal Anxiety, Stress, Hemodynamics, and Neonatal Out NCT07343843 | Benha University | N/A |
| Not Yet Recruiting | Safety Exploration and Evaluation of Dexmedetomidine Hydrochloride Nasal Spray for Pre-anesthesia Sedation in NCT07298525 | Sichuan Provincial People's Hospital | Phase 4 |
| Recruiting | Impact of Perioperative Dexmedetomidine and Esketamine on Postoperative Quality of Recovery NCT07308756 | Peking University First Hospital | Phase 4 |
| Not Yet Recruiting | Role of Opioid Free Anaesthesia in Elderly Patients Undergoing Elective Coronary Artery Bypass Graft Surgeries NCT07360327 | Ain Shams University | N/A |
| Recruiting | Intravenous Lidocaine Infusion Versus Intravenous Dexmedetomidine Infusion During Sleeve Gastrectomy NCT07327905 | Alexandria University | N/A |
| Not Yet Recruiting | Dexamethasone, Dexmedetomidine and Their Combination on Post op. GIT Function Measured by I-FFED Score Post La NCT07329933 | Benha University | N/A |
| Not Yet Recruiting | Dexmedetomidine-Esketamine Combination for Sedation and Analgesia in ICU Patients NCT06468436 | Peking University First Hospital | N/A |
| Completed | Comparing Doses of Intrathecal Dexmedetomidine NCT07395271 | Bahria International Hospital | Phase 4 |
| Recruiting | Sedation With Dexmedetomidine-esketamine Combination and Delirium in ICU Patients NCT07151716 | Peking University First Hospital | Phase 4 |
| Recruiting | Intrathecal Dexmedetomidine-Fentanyl Combination Versus Fentanyl Alone as Adjuvant to Bupivacaine in Spinal An NCT07276867 | National Cancer Institute, Egypt | N/A |
| Recruiting | The Efficacy and Safety of Pregabalin Combined With Dexmedetomidine in Patients With Fibromyalgia NCT07230197 | Beijing Tiantan Hospital | N/A |
| Not Yet Recruiting | D-FAB-POUR Trial: Dexmedetomidine vs Fentanyl as Adjuvants to Bupivacaine on Postoperative Urinary Retention NCT07117565 | Tribhuvan University Teaching Hospital, Institute Of Medicine. | Phase 4 |
| Recruiting | Do Increasing Preoperative Timing of Single Dexmedetomidine Dose Have an Effect on Stress Response of Laryngos NCT07165483 | Tanta University | N/A |
| Completed | Dexmedetomidine-esketamine-ropivacaine Versus Sufentanil-ropivacaine for Epidural Labor Analgesia NCT07145775 | Peking University First Hospital | Phase 4 |
| Not Yet Recruiting | Dexmedetomidine Nasal Spray for the Treatment of Panic Attacks in Adults NCT07162649 | Yuan Shen | N/A |
| Not Yet Recruiting | The Effect of Dexmedetomidine on Postoperative Cognitive Function in Geriatric Patients NCT07047898 | Ankara Etlik City Hospital | N/A |
| Completed | Efficacy of Nebulized Dexmedetomidine on Blunting Hemodynamic Changes During Intubation and Pneumoperitoneum i NCT07054138 | Tanta University | N/A |
| Recruiting | The Effect of Dexmedetomidine on Agitation During Weaning From Mechanical Ventilation NCT07066605 | Sohag University | N/A |
| Recruiting | Dexmedetomidine as an Adjuvant to Bupivacaine in Scalp Block Versus Bupivacaine Alone for Postoperative Pain M NCT06993922 | Ain Shams University | N/A |
| Completed | Infusion of Dexmedetomidine Versus Lidocaine in Management of Acute Postoperative Pain After Modified Radical NCT06974656 | Cairo University | N/A |
| Not Yet Recruiting | Intravenous Lidocaine Plus Intratracheal Dexmedetomidine on Postoperative Sore Throat NCT06952309 | Anqing Municipal Hospital | N/A |
| Recruiting | Intraoperative Infusion of Either Lidocaine or Dexmedetomidine on Regional Cerebral Oxygen Saturation and Post NCT07108764 | Tanta University | N/A |
| Completed | Effect of Dexmedetomidine and Total Intravenous Anesthesia on Endothelial Damage-Related Biomarkers NCT06897696 | Firat University | Phase 4 |
| Recruiting | Dexmedetomidine Versus Lidocaine Infusions as Adjuvants to General Anesthesia for Chronic Pain Management Afte NCT06910644 | Cairo University | N/A |
| Recruiting | Application of Remimazolam, Dexmedetomidine, and Esketamine in Pediatric Preoperative Sedation NCT07050212 | Maternal and Child Health Hospital of Hubei Province | N/A |
| Recruiting | Dexmedetomidine-Esketamine Combination and Sleep Disturbances After Major Noncardiac Surgery NCT06859892 | Peking University First Hospital | Phase 4 |
| Recruiting | Determination of ED50 and ED95 With Clinical Efficacy of Intranasal Dexmedetomidine Combined With Esketamine f NCT06853431 | Second Affiliated Hospital of Wenzhou Medical University | Phase 4 |
| Recruiting | Lidocaine and Dexmedetomidine Infusions for Intraoperative Bleeding in Functional Endoscopic Sinus Surgery NCT06848764 | Ain Shams University | N/A |
| Recruiting | Lidocaine and Dexmedetomidine Infusion and Their Combination on Perioperative Pain in Patients Undergoing Vide NCT06837519 | Ain Shams University | N/A |
| Completed | Impact of Adding Dexmedetomidine as an Adjuvant to The Local Anesthetic in Quadratus Lumborum Block in Patient NCT07072650 | Majid Fakhir Mutar Alhamaaidah | Phase 1 |
| Completed | Procedural Sedation in Renal Sympathetic Denervation NCT07293273 | Ebru Girgin Dinc | — |
| Completed | Magnesium vs. Dexmedetomidine in TURBT Under Spinal Anesthesia NCT07445451 | Dr. Lutfi Kirdar Kartal Training and Research Hospital | N/A |
| Not Yet Recruiting | Dexmedetomidine and Kidney Transplantation NCT05935293 | Eduardo Schiffer | Phase 4 |
| Completed | Dexmedetomidine as an Adjuvant in External Oblique Intercostal Plane Block for Post Thoracotomy Pain NCT06684535 | Tanta University | N/A |
| Not Yet Recruiting | Role of Dexmedetomidine as Synergistic Agent NCT06662175 | Lady Reading Hospital, Pakistan | Phase 2 / Phase 3 |
| Not Yet Recruiting | The Impact of a Dexmedetomidine Perfusion on Intraoperative Remifentanil Consumption NCT06684197 | Ciusss de L'Est de l'Île de Montréal | N/A |
| Completed | Effect of Dexmedetomidine on Gastric Emptying, Assessed by Ultrasound in Laparoscopic Cholecystectomy NCT06634524 | Tanta University | N/A |
| Recruiting | Clinical Study of Perioperative Sleep Disorders in Cardiac Surgery NCT06778811 | Nanjing First Hospital, Nanjing Medical University | Phase 4 |
| Completed | Different Doses of Dexmedetomidine Combined With Esketamine in Women Undergoing Cesarean Delivery NCT06613243 | Peking University First Hospital | Phase 4 |
| Recruiting | Mini-dose Dexmedetomidine-Esketamine Supplemented Analgesia in Patients at High-risk of OSA NCT06566482 | Peking University First Hospital | Phase 4 |
| Completed | Dexmedetomidine-esketamine Combined Nasal Administration and Emergence Delirium NCT06566469 | Peking University First Hospital | Phase 4 |
| Completed | Adding Dexmedetomidine to Mannitol to Attenuate the Increase of Intracranial Pressure NCT07064720 | Cairo University | Phase 2 / Phase 3 |
| Completed | Fentanyl and Dexmedetomidine as Adjuvants to Bupivacaine in Ultrasound-guided Superficial Cervical Plexus Bloc NCT07057739 | Kafrelsheikh University | N/A |
| Recruiting | Effect of Dexmedetomidine and Esketamine on Catheter-related Bladder Discomfort NCT06399185 | Peking University First Hospital | Phase 4 |
| Recruiting | Systemic Versus Local Dexmedetomidine as An Adjuvant to Bupivacaine in Ultrasound Guided Erector Spinae Block NCT06386770 | Aswan University | Phase 3 |
| Completed | Analgesic Efficacy of Adding Dexmedetomidine to Erector Spinae Plane Block Versus Subcostal Transverse Abdomin NCT07075913 | Kafrelsheikh University | N/A |
| Completed | General Anesthesia Versus Sedation By Dexmedetomidine and Ketamine With Local Infiltration for Percutaneous Tr NCT06431178 | Tanta University | N/A |
| Recruiting | Dexmedetomidine in Non-intubated VATS NCT05863416 | Tri-Service General Hospital | Phase 4 |
| Completed | Different Doses of Dexmedetomidine in External Oblique Intercostal Plane Block in Splenectomy NCT06363578 | Tanta University | N/A |
| Completed | Intraoperative Dexmedetomidine Infusion in Endovascular Intervention for Aneurysmal Subarachnoid Hemorrhage NCT06352593 | Tanta University | N/A |
| Recruiting | Effect of Dexmedetomidine Supplementation to General Anaesthesia in Paediatric Transcatheter Closure of Atrial NCT06631534 | Alexandria University | Phase 4 |
| Completed | Efficacy of Intraoperative Magnesium Sulphate vs Dexmedetomidine on Emergence Agitation in Pediatric Patients NCT06977425 | Ain Shams University | N/A |
| Not Yet Recruiting | Effect of Dexmedetomidine on Oxygenation and Lung Mechanics NCT06355960 | Cairo University | N/A |
| Completed | Dexmedetomidine and Ketamine as an Adjuvant in External Oblique Intercostal Plane Block for Post Thoracotomy P NCT06331182 | Tanta University | N/A |
| Completed | Dexmedetomidine as an Adjuvant to Bupivacaine in Scalp Block vs Bupivacaine Alone for Hemodynamics Stability i NCT06951256 | Ain Shams University | N/A |
| Unknown | Adding Dexmedetomidine to Bupivacaine for Bilateral Erector Spinae Block NCT06231979 | Assiut University | Phase 4 |
| Completed | Effect of Dexmedetomidine on Improving Intubating Conditions Without the Use of Muscle Relaxant NCT06409377 | Theodor Bilharz Research Institute | Phase 4 |
| Completed | Dexmedetomidine in Obturator Nerve Block as an Analgesic in Transurethral Surgeries NCT06229054 | Cairo University | EARLY_Phase 1 |
| Active Not Recruiting | Dexamethasone and Dexmedetomidine Versus Dexmedetomidine Alone With Bupivacaine in Ultrasound Guided Rectus Sh NCT06942884 | sarah mohamed | N/A |
| Recruiting | Different Dose Esketamine and Dexmedetomidine for Supplemental Analgesia and Longterm Outcomes NCT06087510 | Peking University First Hospital | Phase 4 |
| Unknown | Dexmedetomidine Infusion Dose Versus Rapid Bolus Dose Before Tracheal Intubation. NCT06327399 | Kasr El Aini Hospital | Phase 2 |
| Completed | Propofol-Fentanyl-Dexmedetomidine and Propofol-Fentanyl-Sevoflurane Anesthesia for Major Spine Surgery Under S NCT06210061 | Ain Shams University | N/A |
| Completed | Effect of Dexmedetomidine on Central Nervous System Complications in Patients Undergoing Cardiac Surgery NCT06551259 | Chinese PLA General Hospital | Phase 4 |
| Completed | Nerve Block Vs Sedation Infusion for Awake Fiberoptic Intubation. NCT06651905 | Cairo University | N/A |
| Terminated | Propofol + Remifentanil vs. Propofol + Dexmedetomidine in Adolescent Idiopathic Scoliosis Patients Having Spin NCT06096181 | Cedars-Sinai Medical Center | Phase 2 |
| Recruiting | Intranasal Dexmedetomidine for Pain Management During Screening for Retinopathy of Prematurity NCT06067958 | Assaf-Harofeh Medical Center | Phase 3 |
| Unknown | Dexmedetomidine Prevents Postoperative Delirium After Deep Brain Stimulation in Patients With Parkinson's Dise NCT05197439 | Beijing Tiantan Hospital | N/A |
| Unknown | Aminophylline on Perioperative Lung Mechanics in COPD Morbidly Obese Patients Undergoing Laparoscopic Bariatri NCT06125665 | Tanta University | N/A |
| Recruiting | Dexmedetomidine, Ozone and Dexamethasone Local Injection in Carpal Tunnel Syndrome for Pain Relief NCT06133712 | Tanta University | N/A |
| Recruiting | Mini-dose Dexmedetomidine-Esketamine Infusion and Perioperative Sleep Quality NCT05950646 | Peking University First Hospital | Phase 4 |
| Completed | Night-time Dexmedetomidine-esketamine Infusion and Sleep Quality in ICU Patients NCT05718024 | Peking University First Hospital | Phase 4 |
| Terminated | Effects of Atomized Dexmedetomidine on Lung Function in Patients With Chronic Obstructive Pulmonary Disease NCT06207331 | The Second Affiliated Hospital of Chongqing Medical University | N/A |
| Completed | Dexmedetomidine and Propofol in Mechanically Ventilated Patients by Using Salivary Alpha-amylase as a Stress M NCT06098209 | Tanta University | N/A |
| Active Not Recruiting | Different Dose Esketamine and Dexmedetomidine Combination for Supplemental Analgesia After Scoliosis Correctio NCT06062550 | Peking University First Hospital | Phase 4 |
| Recruiting | Evaluation of the Hemodynamic Effect of Dexmedetomidine in Scheduled Outpatient Surgery NCT06082856 | Centre Hospitalier Universitaire de Nīmes | N/A |
| Unknown | Nebulization Versus Spray-as-You-Go Airway Topical Anesthesia Using Dexmedetomidine and Lidocaine Mixture Duri NCT06088875 | Tanta University | N/A |
| Completed | Dexmedetomidine-esketamine for Percutaneous Radiofrequency Liver Ablation NCT06003218 | Peking University First Hospital | N/A |
| Unknown | Dexmedetomidine Infusion Versus Oral Melatonin for Prevention of Intensive Care Delirium NCT06076668 | Tanta University | N/A |
| Completed | Efficacy and Safety of Dexmedetomidine to Bupivacaine in Supraclavicular Brachial Plexus Block NCT06020781 | Kafrelsheikh University | N/A |
| Recruiting | Perioperative Dexmedetomidine and Long-term Survival After Cancer Surgery NCT06030804 | Peking University First Hospital | N/A |
| Completed | Dexmedetomidine as an Intrathecal Adjuvant to Hyperbaric Bupivacaine for Postoperative Analgesia in Patients U NCT06667024 | Tanta University | N/A |
| Recruiting | The Effects of Anesthetics on Brain Network Connectivity in Patients With Supratentorial Glioma NCT06138340 | Beijing Tiantan Hospital | — |
| Unknown | Preoperative Nebulized Dexmedetomidine on Hemodynamic Changes in Laparoscopic Bariatric Surgery. NCT06014359 | Tanta University | N/A |
| Completed | Dexmedetomidine as an Adjuvant to Bupivacaine in Ultrasound-Guided Quadratus Lumborum Block for Postoperative NCT06825286 | Tanta University | N/A |
| Unknown | Different Administration Routes of Dexmedetomidine on Postoperative Delirium NCT05952050 | Boston Intelligent Medical Research Center, Shenzhen United Scheme Technology Co., Ltd. | N/A |
| Unknown | Dexmedetomidine in Topical Versus Peribulbar Anesthesia for Cataract Surgery NCT05692167 | Kafrelsheikh University | Phase 2 |
| Unknown | Evaluating Sublingual Dexmedetomidine For Moderate To Severe Agitation In Inpatients With Schizophrenia Or Bip NCT06093451 | Temple University | Phase 4 |
| Completed | Serratus Anterior Plane Block Versus Erector Spinae Plane Block With Dexmedetomidine Added to Bupivacaine for NCT06737458 | Kafrelsheikh University | N/A |
| Completed | Dexmedetomidine Versus Magnesium Sulfate as Adjuvants to Intraperitoneal Bupivacaine for Postoperative Analges NCT06879288 | Tanta University | N/A |
| Recruiting | Fentanyl Versus Dexmedetomidine as an Adjuvant to Bupivacaine in Spinal Anesthesia ; Peritoneal Symptomatic Ef NCT06386783 | Aswan University | Phase 3 |
| Unknown | Hemodynamic Responses of Dexmedetomidine, Lidocaine or Propofol Infusions During Laparoscopic Cholecystectomy NCT05937282 | Menoufia University | Phase 4 |
| Completed | Nasal Packing Versus Intravenous Dexmedetomidine in Turbinate Surgeries NCT05911776 | Kafrelsheikh University | Phase 4 |
| Unknown | The Effects of Dexmedetomidine on Thiol/Disulphide Homeostasis in Coronary Bypass Surgery NCT05895331 | Ankara Etlik City Hospital | — |
| Recruiting | Impact of Erector Spinae Plane Block on Chronic Postsurgical Pain in Breast Cancer Patients NCT05494502 | Peking University First Hospital | N/A |
| Completed | Dexmedetomidine-esketamine Combined Nasal Administration and Perioperative Sleep Quality NCT05732064 | Peking University First Hospital | Phase 4 |
| Unknown | Dexmedetomidine, Ketamine and Magnesium Sulphate in Caudal Block for Hypospadias Repair NCT05837000 | Kafrelsheikh University | Phase 4 |
| Completed | Morphine and Dexmedetomidine as Adjuvants to Bupivacaine in Ultrasound-guided Erector Spinae Plane Block for O NCT07012590 | Kafrelsheikh University | N/A |
| Unknown | Dexmedetomidine and Morphine as Adjuvants to US Guided Erector Spinae Plane Blocks in Elective Thoracic Surger NCT05843344 | Dr Kassiani Theodoraki | N/A |
| Completed | Effect of Dexmedetomidine on Lung Protection in Elderly Patients Undergoing Laparoscopic Surgery for Colorecta NCT07385898 | The Second Affiliated Hospital of Chongqing Medical University | N/A |
| Completed | Analgesic and Sedative Effect of Fentanyl Versus Dexmedetomidine Infusion in Post-Operative Mechanically Venti NCT06994273 | Tanta University | N/A |
| Completed | Dexmedetomidine Versus General Anesthesia on the Diagnosis of Endobronchial US-Guided Transbronchial Needle As NCT05781035 | Kafrelsheikh University | N/A |
| Unknown | Dexmedetomidine vs Ketofol on Delirium in Children Undergoing Congenital Inguinal Hernia Repair NCT05786833 | Tanta University | N/A |
| Completed | Impact of Two Different Types of Sedation on ICEB NCT05757063 | Ankara City Hospital Bilkent | N/A |
| Completed | Aminophylline on Recovery in Functional Endoscopic Sinus Surgery Under Dexmedetomidine Hypotensive Anesthesia NCT05738135 | Tanta University | N/A |
| Completed | Comparison of Recovery Profiles Among Propofol, Remimazolam, and Dexmedetomidine After Intraoperative Sedation NCT05688345 | Asan Medical Center | Phase 4 |
| Recruiting | Two-channel IV-PCA With Dexmedetomidine NCT05672225 | Korea University Guro Hospital | N/A |
| Recruiting | Effect of Different Administration Routes of Dexmedetomidine Combined with Ultrasound-Guided Fascia Iliaca Blo NCT06614010 | Qianfoshan Hospital | Phase 1 |
| Unknown | Dexmedetomidine Plus Low Dose Morphine Versus Standard Dose of Morphine in PCA in Children . NCT05688371 | Beni-Suef University | N/A |
| Completed | Mini-dose Esketamine-dexmedetomidine Supplemented Analgesia and Long-term Outcomes NCT05718544 | Peking University First Hospital | Phase 4 |
| Unknown | Intranasal Dexmedetomidine Versus Intravenous Dexmedetomidine for Improving Quality of Endoscopic Sinus Surger NCT06081933 | Kafrelsheikh University | Phase 4 |
| Completed | Pregabalin Versus Dexmedetomidine for Delirium Prevention After Cardiac Surgery NCT05640479 | Tanta University | Phase 4 |
| Recruiting | Pregabalin Versus Dexmedetomidine for Delirium Treatment After Coronary Artery Bypass Grafting NCT05640453 | Tanta University | Phase 4 |
| Unknown | Intranasal Dexmedetomidine in Children Undergoing Adenotonsillectomy Suffering From Mild Upper Respiratory Tra NCT05639777 | Tanta University | Phase 4 |
| Unknown | The Impact of a Single Dexmedetomidine Bolus on Intraoperative Sevoflurane Consumption (DEXHALE) NCT05615194 | Ciusss de L'Est de l'Île de Montréal | N/A |
| Completed | Esketamine Combined With Dexmedetomidine Sedation in Head MRI Examination of Children With Autism Spectrum Dis NCT06633315 | Maternal and Child Health Hospital of Hubei Province | Phase 2 |
| Unknown | Intranasal vs. IV Dexmedetomidine in Endoscopic Sinus Surgery NCT05595083 | Kafrelsheikh University | N/A |
| Recruiting | Choice of Anesthesia in Microelectrode Recording Guided Deep Brain Stimulation for Parkinson's Disease NCT05550714 | Beijing Tiantan Hospital | N/A |
| Completed | Effect of Intraarticular Ozone, Prolotherapy or Dexmedetomidine in Pain Limitation in Knee Osteoarthritis NCT06909305 | Tanta University | N/A |
| Unknown | Intrathecal Versus Intravenous Dexmedetomidine in Prostate Transurethral Resection NCT05525819 | Tanta University | N/A |
| Recruiting | Safety and Efficacy of Esketamine Combined With Dexmedetomidine for Sedation of Mechanically Ventilated Patien NCT05466708 | The First Affiliated Hospital with Nanjing Medical University | Phase 4 |
| Unknown | Opioid Sparing Anesthesia in Lumbar Spine Surgery NCT05594407 | Aretaieion University Hospital | N/A |
| Recruiting | Intraoperative Infusion of Dexmedetomidine for Prevention of Postoperative Delirium in Elderly Patients NCT05168280 | Beijing Tiantan Hospital | N/A |
| Withdrawn | Nocturnal Low-dose Dexmedetomidine Infusion and Perioperative Sleep Quality NCT05246007 | Peking University First Hospital | N/A |
| Unknown | Prospective, Randomized, Open Label Controlled Trial To Evaluate The Safety And Efficacy Of Dexmedetomidine Us NCT05485519 | King Abdullah International Medical Research Center | Phase 3 |
| Unknown | Bupivacaine Alone vs Bupivacaine and Dexmed in Cesarean Deliveries NCT05469529 | KRL Hospital, Islamabad | N/A |
| Recruiting | Effect of Dexmedetomidine on Postoperative Delirium After Awake Craniotomies NCT05195034 | Beijing Tiantan Hospital | N/A |
| Completed | Dexmedetomine as Adjuvant for Spinal Anesthesia in Elective Cesarian Sections : a Pilot Study NCT05099055 | St. Justine's Hospital | Phase 3 |
| Unknown | Intranasal Dexmedetomidine Versus Oral Midazolam as Premedication for Propofol Sedation in Pediatric Patients NCT05192629 | Brugmann University Hospital | Phase 3 |
| Unknown | Opioid-free Anesthesia in Thyroidectomies NCT05243940 | Aretaieion University Hospital | N/A |
| Completed | Comparison of the Effects of Remifentanil and Dexmedetomidine Administered Under General Anesthesia in Rhinopl NCT05572723 | Baskent University | Phase 4 |
| Completed | Dexmedetomidine Different Doses as Adjuvant to Entropy-assisted General Anesthesia During Functional Endoscopy NCT05226325 | Cairo University | N/A |
| Unknown | IV Dexmedetomidine in the Duration of Spinal Anesthesia With Hyperbaric Bupivacaine: Double Blind Randomized T NCT05335655 | Hospital Central "Dr. Ignacio Morones Prieto" | Phase 3 |
| Unknown | Study on the Difference and Cause of Acupuncture Dexmedetomidine Compound Anesthesia Effect NCT05159674 | Shanghai Yueyang Integrated Medicine Hospital | N/A |
| Completed | Determination of Optimum Time for Intravenous Cannulation in Children With Dexmedetomidine Premedication NCT05139212 | Karaman Training and Research Hospital | — |
| Terminated | Dexmedetomidine Supplemented Analgesia and Delirium After Hip Fracture Surgery NCT04955249 | Peking University First Hospital | Phase 4 |
| Completed | The Neuroprotective Effect of Dexmedetomidine Preserving Brain Functional Connectivity in Elderly Patients NCT04973124 | Pontificia Universidad Catolica de Chile | N/A |
| Unknown | A Comparative Study to Measure the Effect of Nebulized Dexmedetomidine NCT05158348 | Kasr El Aini Hospital | Phase 3 |
| Completed | Dexmedetomidine and Long-term Outcomes in Elderly Patients After Cardiac Surgery NCT03289325 | Peking University First Hospital | N/A |
| Unknown | Opioid-free Anesthesia in Laparoscopic Cholecystectomies NCT05089526 | Aretaieion University Hospital | N/A |
| Completed | Propofol-remifentanyl Versus Dexmedetomidine in Awake Craniotomy: Impact on Electroclinical Seizure Activity NCT05103735 | Azienda Sanitaria-Universitaria Integrata di Udine | — |
| Unknown | The Effect of Dexmedetomidine on Kidney Function in EVAR NCT04766047 | University of Thessaly | N/A |
| Completed | Attenuation Of Hemodynamic Response To Laryngoscopy. Role Of Dexmedetomidine. A Dose Finding Study NCT05909215 | Sindh Institute of Urology and Transplantation | Phase 4 |
| Terminated | Low-Dose Dexmedetomidine for Delirium Prevention in Mechanically Ventilated Septic Patients NCT04876937 | Peking University First Hospital | N/A |
| Completed | Dexmedetomidine vs Fentanyl on Time to Extubation in Patients Undergoing Laparoscopic Sleeve Gastrectomy NCT06052111 | Helwan University | N/A |
| Unknown | Effect of Multimodal Opioid-free Anesthesia on Return of Bowel Function in Laparoscopic Colorectal Surgery NCT04144933 | University of Saskatchewan | Phase 3 |
| Completed | Low-dose S-ketamine and Dexmedetomidine in Combination With Opioids for Postoperative Analgesia NCT04791059 | Peking University First Hospital | Phase 4 |
| Unknown | Opioid-free Anesthesia With a Mixture of Dexmedetomidine-lidocaine-ketamine NCT04858711 | Aretaieion University Hospital | N/A |
| Unknown | Dexamethasone and Dexmedetomidine as Adjuvants to Ropivacaine in Ultrasound-guided Multilevel Thoracic Paraver NCT04763434 | Gansu Provincial Hospital | Phase 4 |
| Completed | Intravenous Dexamethasone and Dexmedetomidine on the Analgesic Efficacy of Erector Spinae Plane Block NCT04767256 | Huazhong University of Science and Technology | N/A |
| Completed | Comparison Of Dexmedetomidine And Dexamethasone As An Adjuvant To Bupivacaine In Brachial Plexus Block NCT04791475 | Tribhuvan University Teaching Hospital, Institute Of Medicine. | N/A |
| Completed | Dexmedetomidine Supplemented Analgesia in Patients at High-risk of Obstructive Sleep Apnea NCT04608331 | Peking University First Hospital | Phase 4 |
| Completed | Effect of Co-administration Lidocaine and Dexmedetomidine on Quality of Recovery NCT04706767 | Anqing Municipal Hospital | N/A |
| Completed | Dexmedetomidine Alleviates Postoperative Delirium After Brain Tumor Resections NCT04674241 | Beijing Tiantan Hospital | N/A |
| Completed | Intranasal Dexmedetomidine Versus Intranasal Midazolam for MRI In Pediatrics NCT04652661 | Tanta University | Phase 4 |
| Completed | Dexmedetomidine as an Adjuvant for Femoral Nerve Block and Functional Recovery After Total Knee Arthroplasty NCT04642651 | Peking University First Hospital | Phase 4 |
| Completed | The Effects of Mild Sedation on Motor Function Networks in Patients With Brian Gliomas NCT03984240 | Beijing Tiantan Hospital | N/A |
| Unknown | Intrathecal Versus Intravenous Dexmeditomedine in Transurethral Resection of the Prostate NCT04618965 | Tanta University | Phase 4 |
| Completed | Dexmedetomidine in Splanchnic Nerve Neurolysis NCT05291364 | Minia University | N/A |
| Unknown | Dexmedetomidine and Sufentanil Effect in PCA on Pediatric Patients Undergoing Scoliosis Surgery NCT05249153 | Peking Union Medical College Hospital | N/A |
| Completed | Dexmedetomidine and Melatonin for Sleep Induction for EEG in Children NCT04665453 | University Medical Centre Ljubljana | N/A |
| Active Not Recruiting | Dexmedetomidine and Outcomes of Elderly Admitted to ICU After Surgery NCT04204798 | Peking University First Hospital | N/A |
| Unknown | Determining the Pharmacogenetic Basis of Non-responsiveness to the Sedative Effects of Dexmedetomidine in Chil NCT04471402 | Hong Kong Children's Hospital | — |
| Completed | Dexmedetomidine or Fentanyl as Additives to Epidural Levobupivacaine in Painless Labor NCT04397406 | Tanta University | Phase 4 |
| Completed | Caudal Ropivacaine With or Without Dexmedetomidine for Post Operative Analgesia NCT05979558 | National Academy of Medical Sciences, Nepal | N/A |
| Completed | Effect of Intratracheal Dexmedetomidine Administration on Recovery From General Anesthesia in Pediatrics Under NCT04385602 | Assiut University | Phase 2 / Phase 3 |
| Unknown | Dexmedetomidine to Improve Outcomes of ARDS in Critical Care COVID-19 Patients NCT04358627 | Hospital Clinic of Barcelona | — |
| Completed | Intranasal Dexmedetomidine for Deep-sedated Pediatric Dental Patients NCT04509414 | Peking University | Phase 4 |
| Completed | Dexmedetomidine to Levobupivacaine for Transversus Abdominis Plane Block in Elderly Patients Undergoing Inguin NCT04971759 | Assiut University | Phase 2 / Phase 3 |
| Recruiting | Cognitive Outcomes After Dexmedetomidine Sedation in Cardiac Surgery Patients NCT04289142 | Sunnybrook Health Sciences Centre | Phase 4 |
| Completed | Effects of Dexmedetomidine on Cardiac Electrophysiology in Patients Under General Anesthesia During Perioperat NCT04577430 | Yangzhou University | N/A |
| Completed | Effect of Two Different Doses of Dexmedetomidine Infusion in Morbidly Obese Patients NCT06018948 | Tanta University | Phase 4 |
| Unknown | The Mechanism of Dexmedetomidine in Improving Delirium After Cardiac Surgery NCT04127500 | Nanjing First Hospital, Nanjing Medical University | N/A |
| Terminated | DOSE Trial of Opioid Sparing Effect NCT03938857 | Duke University | Phase 1 |
| Completed | The Deep Sedation for Ablation Study NCT03844841 | Insel Gruppe AG, University Hospital Bern | Phase 4 |
| Completed | Atropine or Ephedrine Pretreatment for Preventing Bradycardia in Elderly Patients NCT03984526 | Ajou University School of Medicine | Phase 4 |
| Completed | Dexmedetomidine Combined With Lidocaine Infusion Affect PONV NCT03809923 | Anqing Municipal Hospital | N/A |
| Completed | Intraoperative Goal-directed Blood Pressure and Dexmedetomidine on Outcomes NCT03933306 | Peking University First Hospital | Phase 4 |
| Unknown | The Neuroprotection Effect of Dexmedetomidine NCT03927963 | Ajou University School of Medicine | N/A |
| Active Not Recruiting | Low-dose Dexmedetomidine and Postoperative Delirium After Cardiac Surgery NCT03624595 | Dong-Xin Wang | N/A |
| Completed | Single-shot Adductor Canal Block With Levobupivacaine and Dexmedetomidine in Total Knee Arthroplasty NCT04968392 | Assiut University | Phase 2 / Phase 3 |
| Terminated | Dexmedetomidine Combined With Ropivacaine for Postoperative Continuous Femoral Nerve Block NCT03629483 | Peking University First Hospital | Phase 4 |
| Completed | Dexmedetomidine Supplemented Intravenous Analgesia in Elderly After Orthopedic Surgery NCT03629262 | Peking University First Hospital | Phase 4 |
| Completed | Intranasal Dexmedetomidine Sedation in Children for Non-painful Procedures NCT03220880 | Columbia University | — |
| Completed | Dexmedetomidine as Adjuvant for FNB in TKA NCT03658421 | First Affiliated Hospital, Sun Yat-Sen University | N/A |
| Completed | Low Dose Hyperbaric Bupivacaine and Dexmedetomidine as an Adjuvant, Caesarean Section NCT03775655 | Menoufia University | Phase 2 / Phase 3 |
| Active Not Recruiting | Dexmedetomidine to Reduce the Incidence of POCD After Open Cardiac Surgery NCT03480061 | Sunnybrook Health Sciences Centre | Phase 4 |
| Terminated | Pharmacokinetic Study of Intranasal Dexmedetomidine in Pediatric Patients With Congenital Heart Disease NCT03417999 | Children's Hospital of Philadelphia | Phase 1 |
| Unknown | Acceptable Hemodynamic Changes in Dexmedetomidine for Single Intravenous Bolus Injection NCT03655847 | Second Affiliated Hospital of Wenzhou Medical University | Phase 4 |
| Completed | Comparison of Intra-articular Dexmedetomidine and Magnesium in Postoperative Pain NCT03479216 | Derince Training and Research Hospital | Phase 4 |
| Completed | Sedation Of Adult Patients Undergoing Gastrointestinal Endoscopy: A Network Meta-analysis NCT03632330 | Pfizer | — |
| Completed | Effect of Lidocaine Plus Dexmedetomidine Infusion on PONV NCT03788018 | Xu Siqi | N/A |
| Completed | Dexmedetomidine Improves the Surgical Field and Postoperative Recovery of Nasal Endoscopic Surgery NCT04276545 | Eye & ENT Hospital of Fudan University | Phase 3 |
| Completed | Impacts of Low-Dose Dexmedetomidine on Sleep Quality in Mechanically Ventilated ICU Patients NCT03335527 | Peking University First Hospital | Phase 4 |
| Completed | Effects of Dexmedetomidine on Modulation of Perioperative Blood Glucose and Related Hormones NCT03788538 | Zhuan Zhang | N/A |
| Unknown | Pharmacodynamics and Pharmacokinetics of Dexmedetomidine in Pediatric NCT03337581 | Chinese Medical Association | Phase 4 |
| Completed | Efficacy of Opioid-free Anesthesia in Reducing Postoperative Respiratory Depression in Children Undergoing Ton NCT02987985 | University of Saskatchewan | Phase 3 |
| Terminated | Magnesium and Postoperative Pain NCT03253224 | Seoul National University Hospital | Phase 4 |
| Completed | Dexmedetomidine and Neuroprotection in Children Undergoing General Anesthesia NCT03234660 | Seoul National University Hospital | N/A |
| Suspended | Low-dose Dexmedetomidine in Mechanically Ventilated ICU Patients NCT03172897 | Peking University First Hospital | Phase 4 |
| Completed | Impact of Dexmedetomidine on Sleep Quality NCT03117790 | Peking University First Hospital | Phase 4 |
| Completed | Intraoperative Sedatives and Postoperative Deilirium NCT03251651 | Seoul National University Bundang Hospital | N/A |
| Completed | Dexmedetomidine and 5-year Outcome in Elderly Patients After Surgery NCT03436472 | Peking University First Hospital | N/A |
| Unknown | Dexmedetomidine on Basal Ganglia Neuronal Activity in Parkinson's Disease NCT02982512 | Clinica Universidad de Navarra, Universidad de Navarra | Phase 4 |
| Completed | Dexmedetomidine Supplemented Analgesia and Incidence of Postoperative Delirium NCT03012984 | Peking University First Hospital | N/A |
| Completed | Dexmedetomidine Supplemented Analgesia and Long-term Survival After Cancer Surgery NCT03012971 | Peking University First Hospital | N/A |
| Completed | Dexmedetomidine vs Midazolam on Resting Energy Expenditure in Critically Ill Patients NCT03030911 | Cairo University | Phase 4 |
| Completed | Effect of Dexmedetomidine on Perioperative Internal Environment and Rehabilitation of Patients Undergoing Gast NCT04771637 | Yangzhou University | N/A |
| Completed | Lidocaine 5% Patch Supplementation to Intra-articular Bupivacaine Dexmedetomidine After Arthroscopic Knee Surg NCT04322760 | Tanta University | N/A |
| Completed | The Effect of Dexmedetomidine for Suprascapular Nerve Block With Axillary Nerve Block NCT04398589 | Chuncheon Sacred Heart Hospital | Phase 4 |
| Completed | Sedation and Physiological Effects of Intranasal Dexmedetomidine in Severe COPD NCT02211118 | Dayton VA Medical Center | Phase 4 |
| Completed | Dexmedetomidine in Different Dose Levels as Adjuvant to Bupivacaine-induced Ultrasound-guided Femoral Nerve Bl NCT02089932 | Cairo University | Phase 4 |
| Unknown | Paradoxical Excitement Response During Sedation Between Dexmedetomidine and Propofol in Hazardous Alcohol Drin NCT02197403 | Chonnam National University Hospital | Phase 4 |
| Completed | Pharmacokinetics of Different Mode Administration of Intranasal Dexmedetomidine NCT03323593 | The University of Hong Kong | Phase 3 |
| Completed | Comparison Between Lidocaine, Dexmedetomidine, and Their Combined Infusion in Subjects Undergoing Coronary Art NCT01688648 | Samsung Medical Center | N/A |
| Completed | A Pilot Study to Assess the Amnesic Properties of Dexmedetomidine in Pediatric Patients NCT02354378 | Boston Children's Hospital | — |
| Completed | A Sequential Allocation Study to Determine the ED50 of Dexmetedomidine as an Adjuvant to Lidocaine Intravenous NCT05342870 | American University of Beirut Medical Center | N/A |
| Completed | Comparison of Dexmedetomidine and Remifentanil Infusion During CABG NCT01572454 | Samsung Medical Center | N/A |
| Completed | Dexmedetomidine and Long-term Outcome in Elderly Patients After Surgery NCT02809937 | Peking University First Hospital | Phase 4 |
| Unknown | Sedation of Mechanically Ventilated Critically Ill Patients: Midazolam Versus Dexmedetomidine NCT01256866 | Hospital Sao Domingos | Phase 4 |