NCT05688371

Dexmedetomidine Plus Low Dose Morphine Versus Standard Dose of Morphine in PCA in Children .

Comparison of Addition of Dexmedetomidine to Low Dose Morphine Versus Standard Dose of Morphine in Patiant Controlled Analgesia in Children Undergoing Pelvi Abdominal Exploration. a Prospective Randomized Trial

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 60 (estimated)
• Sponsor: Beni-Suef University · Academic / Other
• Sex: All
• Age: 8 Years – 12 Years
• Healthy volunteers: Not accepted

Summary

The treatment of perioperative pain in children has been a topic of great interest to pediatricians, pediatric surgeons, and anesthesiologists for many years. Opioids are the most common analgesics used to manage acute postoperative pain in children and adults

Detailed description

Patient-controlled analgesia (PCA) permits patients to self-administer small doses of opioid analgesics intravenously or subcutaneously at frequent intervals. PCA is used in the management of moderate-to-severe pain. Patient-controlled analgesia (PCA) is now used in children as young as 5 yr for the treatment of postoperative pain.

Conditions

• PCA
• Children
• Dexmedetomidine
• Morphine

Interventions

Type	Name	Description
DRUG	standard dose morphine	Receiving 0.05 mg morphine/kg as a bolus.
DRUG	low dose morphine plus dexmedetomidine	Receiving 0.02 mg morphine/kg as a bolus dose + 0.2 microgram/kg dexmedetomidine

Timeline

• Start date: 2023-02-01
• Primary completion: 2024-10-01
• Completion: 2024-10-01
• First posted: 2023-01-18
• Last updated: 2024-09-25

Locations

1 site across 1 country: Egypt