NCT05639777

Intranasal Dexmedetomidine in Children Undergoing Adenotonsillectomy Suffering From Mild Upper Respiratory Tract Infection

The Effect of Intranasal Dexmedetomidine Premedication in Children Undergoing Adenotonsillectomy Suffering From Recent Mild Upper Respiratory Tract Infection

• Status: Unknown
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 70 (estimated)
• Sponsor: Tanta University · Academic / Other
• Sex: All
• Age: 3 Years – 10 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to detect the efficacy of intranasal dexmedetomidine as a premedication to general anesthesia in pediatric patients with respiratory comorbidities undergoing adenotonsillectomy.

Detailed description

Respiratory comorbidities are associated with an increased incidence of peri-operative respiratory adverse effects (PRAE). Upper and lower respiratory infections, as well as asthma, are common in children who are scheduled for adenotonsillectomy. When compared to healthy children, children with respiratory ailments have a three-fold increase in PRAEs.

Conditions

• Dexmedetomidine
• Adenotonsillectomy
• Respiratory Tract Infections

Interventions

Type	Name	Description
DRUG	Dexmedetomidine group	That will receive intranasal dexmedetomidine (1.5mcg/kg)
OTHER	control group	That will receive the same volume of 2 ml of intranasal normal saline

Timeline

• Start date: 2022-12-06
• Primary completion: 2023-05-15
• Completion: 2023-05-15
• First posted: 2022-12-06
• Last updated: 2022-12-07

Locations

1 site across 1 country: Egypt