NCT07508202

Comparison of Post Operative Analgesia in Patients Undergoing Lower Abdominal Surgeries Receiving Ultrasound Guided Block With Dexmetomidine vs Dexmethasone

Comparison of Mean Duration of Post Operative Analgesia in Patients Undergoing Lower Abdominal Surgeries Receiving US Transversus Abdominis Plane Block (TAP) With Bupivacaine and Dexmetomidine vs Bupivacaine nd Dexmethasone

• Status: Recruiting
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 60 (estimated)
• Sponsor: Pakistan Institute of Medical Sciences · Other Government
• Sex: All
• Age: 18 Years – 60 Years
• Healthy volunteers: Accepted

Summary

Lower abdominal surgeries cause significant pain and can be managed by injecting local anesthetic agents between muscles of abdominal wall that can provide post operative pain relief and its duration can be prolonged by adding drugs to local anesthetic regimen

Detailed description

TAPP block can provide significant post operative analgesia following lower abdominal surgery and its duration can be prolonged by adding adjuvants to local anesthetics.

Conditions

• Post Operative Analgesia
• Dexmedetomidine
• TAP Block

Interventions

Type	Name	Description
DRUG	Dexmedetomidine	20 ml 0.25% Bupivacaine along with 0.5 Mcg/kg of Dexmedetomidine will be given in TAPP block bilaterally
DRUG	Dexamethasone	20 ml 0.25% Bupivacaine along with 4 mg of Dexamethasone will be given in TAPP block bilaterally

Timeline

• Start date: 2026-03-27
• Primary completion: 2026-06-26
• Completion: 2026-06-26
• First posted: 2026-04-02
• Last updated: 2026-04-02

Locations

1 site across 1 country: Pakistan