Trials / Completed
CompletedNCT05103735
Propofol-remifentanyl Versus Dexmedetomidine in Awake Craniotomy: Impact on Electroclinical Seizure Activity
Propofol-remifentanil Versus Dexmedetomidine in Awake Craniotomy: an Intraoperative Neurophysiological Evaluation
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 170 (actual)
- Sponsor
- Azienda Sanitaria-Universitaria Integrata di Udine · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
Awake craniotomy require a cooperative patient during resection neurosurgery phase. Anesthesiologist should guarantee analgesia, sedation, nausea and vomiting prevention, while maintaining normal vital parameters. Neurosurgeon could be help by Intraoperative electrocorticography to maximise lesion resection and avoiding neurologic sequelae. Propofol and remifentanyl have been largely used. Dexmedetomidine represents an alternative. However little is known about the role of dexmedetomidine on Intraoperative electrocorticography.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Propofol | awake neurosurgery under propofol-remifentanil sedation |
Timeline
- Start date
- 2021-09-15
- Primary completion
- 2021-10-10
- Completion
- 2021-10-11
- First posted
- 2021-11-02
- Last updated
- 2023-01-31
Locations
1 site across 1 country: Italy
Source: ClinicalTrials.gov record NCT05103735. Inclusion in this directory is not an endorsement.