NCT06355960

Effect of Dexmedetomidine on Oxygenation and Lung Mechanics

Effect of Different Does of Dexmedetomidine on Oxygenation and Lung Mechanics

• Status: Not Yet Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 176 (estimated)
• Sponsor: Cairo University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

Dexmedetomidine is a selective α -2 agonist widely used in anesthesia for its sympatholytic, sedative and analgesic effects . Favorable respiratory effects in animals , and in selected human patient groups have been reported when using this agent .we investigated the effects of different doses of dexmedetomidine infusion on oxygenation

Conditions

• Drug Use
• Dexmedetomidine

Interventions

Type	Name	Description
DRUG	GROUP Dexmedetomidine	Dexmedetomidine (Precedex) loadings of 1 μg/kg , then continuously at a rate of 0.2 μg/(kg/h) till the end of the operation .
DRUG	GROUP B	Dexmedetomidine (Precedex) loadings of 0.5 μg/kg , then continuously at a rate of 0.2 μg/(kg/h) till the end of the operation .
DRUG	GROUP C	Dexmedetomidine (Precedex) loadings of 0.25 μg/kg, then continuously at a rate of 0.2 μg/(kg/h) till the end of the operation .

Timeline

• Start date: 2024-04-01
• Primary completion: 2025-04-01
• Completion: 2025-05-01
• First posted: 2024-04-10
• Last updated: 2024-04-10

Locations

1 site across 1 country: Egypt