Trials / Completed
CompletedNCT05738135
Aminophylline on Recovery in Functional Endoscopic Sinus Surgery Under Dexmedetomidine Hypotensive Anesthesia
Effect of Intravenous Aminophylline on Hemodynamics and Recovery of Patients Undergoing Functional Endoscopic Sinus Surgery Under Dexmedetomidine Hypotensive Anesthesia: A Randomized Controlled Study
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 52 (actual)
- Sponsor
- Tanta University · Academic / Other
- Sex
- All
- Age
- 18 Years – 50 Years
- Healthy volunteers
- Accepted
Summary
This study will be conducted to evaluate the effect of intravenous aminophylline on hemodynamics and recovery of patients receiving dexmedetomidine infusion during functional endoscopic sinus surgery.
Detailed description
Aminophylline is a nonselective adenosine receptor antagonist used for the treatment of asthma and chronic obstructive pulmonary disease. It has been used to antagonize the effects of anaesthetic and analgesic agents
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Aminophylline group | Patients will receive 4 mg/kg aminophylline diluted in 50 ml normal saline over 30 minutes. |
| DRUG | normal saline | Patients will receive 50 ml normal saline over 30 minutes. |
Timeline
- Start date
- 2023-02-25
- Primary completion
- 2023-08-25
- Completion
- 2023-08-25
- First posted
- 2023-02-21
- Last updated
- 2023-08-29
Locations
1 site across 1 country: Egypt
Source: ClinicalTrials.gov record NCT05738135. Inclusion in this directory is not an endorsement.