NCT03632330

Sedation Of Adult Patients Undergoing Gastrointestinal Endoscopy: A Network Meta-analysis

SEDATION OF ADULT PATIENTS UNDERGOING GASTROINTESTINAL ENDOSCOPY: A NETWORK META-ANALYSIS

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 6,963 (actual)
• Sponsor: Pfizer · Industry
• Sex: All
• Age: 12 Years
• Healthy volunteers: Not accepted

Summary

The objective of this study is to compare the efficacy and safety of dexmedetomidine with other sedatives in sedation during endoscopy by analyzing the most recently published interventional trials and observational studies.

Detailed description

A variety of sedatives are available in procedural sedation and the efficacy \& safety have been compared in several trials for procedural sedation. However, none of clinical trial has enough number of patients to clarify the conclusive differences among sedatives. Thus, pooling all available studies together systematically by network meta-analysis for GI endoscopic procedure may provide a better understanding of efficacy and safety of sedatives. Therefore we would like to conduct a network meta-analysis to analyze the outcomes of GI endoscopy by using the most recently-published interventional trials.

Conditions

• Gastrointestinal Endoscopy
• Sedation
• Dexmedetomidine

Interventions

Type	Name	Description
DRUG	Dexmedetomidine	Dexmedetomidine group
DRUG	Midazolam	Midazolam group
DRUG	Propofol	Propofol group
DRUG	Midazolam/Propofol	Midazolam/Propofol group

Timeline

• Start date: 2018-02-05
• Primary completion: 2018-03-07
• Completion: 2018-03-07
• First posted: 2018-08-15
• Last updated: 2023-04-06

Locations

1 site across 1 country: South Korea