| Withdrawn | 129Xe MRI in Pediatric Population With BPD NCT04035629 | Xemed LLC | Phase 1 |
| Not Yet Recruiting | High-energy Human Milk Diets in the First Two Weeks After Birth to Reduce BPD in Extremely Preterm Infants NCT07307612 | University of Alabama at Birmingham | Phase 1 / Phase 2 |
| Not Yet Recruiting | Early Prediction of Bronchopulmonary Dysplasia in Preterm Infants Using Clinical Data NCT07525167 | Konya City Hospital | — |
| Not Yet Recruiting | Lipid Infusions to Optimize Nutrition Trial NCT06915441 | The University of Texas Health Science Center, Houston | Phase 2 |
| Recruiting | Pulmonary Hypertension and Oxygen Saturation Targeting in Preterm Infants NCT06373289 | University of Alabama at Birmingham | N/A |
| Not Yet Recruiting | PremaBiom: Metatranscriptomics of the Respiratory Microbiome to Predict the Occurrence of Bronchopulmonary Dys NCT07411261 | University Hospital, Caen | N/A |
| Recruiting | Inhaled Ciclesonide Study in Preterm Infants NCT06589245 | Venkatesh Sampath | Phase 1 |
| Recruiting | Ventilator Pressure and Optimization of Compliance and Hemodynamics NCT06512935 | University of Alabama at Birmingham | N/A |
| Withdrawn | Inhaled Treatment for Bronchopulmonary Dysplasia NCT04619602 | University Hospitals Cleveland Medical Center | Phase 1 |
| Recruiting | Transpyloric Versus Gastric Feeding in Bronchopulmonary Dysplasia NCT06534359 | Children's Hospital of Philadelphia | N/A |
| Recruiting | Restricted Versus Liberal Fluid Intake for Prevention of Bronchopulmonary Dysplasia NCT06954142 | University Children's Hospital Basel | N/A |
| Recruiting | IVIG Trial for the Treatment of Bronchopulmonary Dysplasia NCT06925360 | International Peace Maternity and Child Health Hospital | Phase 2 |
| Recruiting | Prospective Multicentre Mixed Methods Study to Explore Extubation Practices and Respiratory Outcomes in Extrem NCT06808997 | Centre Hospitalier Intercommunal Creteil | — |
| Recruiting | Gastric Feeding Versus Transpyloric Feeding in Infants with Severe Bronchopulmonary Dysplasia, a Crossover Stu NCT06821776 | Le Bonheur Children's Hospital | N/A |
| Recruiting | Efficacy and Safety of Zelpultide Alfa in Preterm Neonates at High Risk of Developing Bronchopulmonary Dysplas NCT06897839 | Airway Therapeutics, Inc. | Phase 2 / Phase 3 |
| Recruiting | Pressure-Sensing Mattresses and Mechanical Ventilation Weaning in Neonatal NCT06579157 | Fu Jen Catholic University | — |
| Not Yet Recruiting | Post-extubation Pressures in Preterm Neonates: A CER Study NCT06552455 | McMaster Children's Hospital | — |
| Completed | THE EFFECT OF NEBULIZED AZITHROMYCIN AS THERAPY FOR BRONCHOPULMONARY DYSPLASIA NCT06584474 | Alexandria University | Phase 4 |
| Unknown | Randomized Controlled Crossover Trial of Postpyloric Feedings to Improve Pulmonary Outcomes in High-risk Prete NCT05777512 | Boston Children's Hospital | N/A |
| Not Yet Recruiting | Comparison of Lung Ultrasound Scores With Clinical Models for Predicting Bronchopulmonary Dysplasia：A Multi-ce NCT06443528 | The First Hospital of Jilin University | — |
| Withdrawn | Fast Assessment of Surfactant Deficiency in Preterm Infants to Speed up Treatment NCT05638568 | Rigshospitalet, Denmark | N/A |
| Recruiting | The Role of Volatile Organic Compounds (VOCs), Airway Mucins and the Microbiome in the Early Prediction of Bro NCT06342752 | University Hospital, Antwerp | — |
| Recruiting | Different Levels of BiPAP NCT06421519 | King's College Hospital NHS Trust | Phase 1 / Phase 2 |
| Completed | Recombinant Surfactant Protein D (rfhSP-D) to Prevent Neonatal Chronic Lung Disease NCT05898633 | University College, London | Phase 1 |
| Recruiting | Optimization of Saturation Targets And Resuscitation Trial (OptiSTART) NCT05849077 | University of Texas Southwestern Medical Center | N/A |
| Recruiting | Use of Mesenchymal Stem Cells in Pre-term Patients With Bronchopulmonary Dysplasia. NCT06270199 | Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal | Phase 2 |
| Unknown | NeO2Matic-Pilot Trial NCT05629910 | Rigshospitalet, Denmark | N/A |
| Recruiting | Safety and Efficacy of MSC-EVs in the Prevention of BPD in Extremely Preterm Infants NCT06279741 | EXO Biologics S.A. | Phase 1 / Phase 2 |
| Recruiting | Multidimensional Phenotype Classification in Grade 3 Bronchopulmonary Dysplasia NCT06475976 | Children's Hospital of Philadelphia | — |
| Recruiting | Frequent Standardized Oral Care Using Human Milk in the Neonatal Intensive Care Unit NCT06000761 | University of Florida | N/A |
| Completed | Relationship Between EIT and Respiratory Status in Very Preterm Infants NCT06609135 | Lawrence Rhein | N/A |
| Unknown | Implementation of a Consensus-Based Discharge Protocol for Preterm Infants With Lung Disease NCT05285345 | Boston Children's Hospital | — |
| Completed | Pragmatic Research on Diuretic Management in Early BPD Pilot NCT05898022 | Children's Hospital Medical Center, Cincinnati | Phase 4 |
| Active Not Recruiting | Enteral High-dose DHA Supplementation on Bronchopulmonary Dysplasia in Very Preterm Infants: a Collaborative S NCT05915806 | CHU de Quebec-Universite Laval | N/A |
| Unknown | Respiratory Oscillometry for the Prediction of Bronchopulmonary Dysplasia NCT05986032 | Fondazione IRCCS San Gerardo dei Tintori | — |
| Enrolling By Invitation | Point of Care Lung Ultrasound in Preterm Infants with Respiratory Distress NCT05925075 | Phoenix Children's Hospital | — |
| Unknown | Comparison of INRECSURE and LISA in Preterm Neonates With RDS NCT05711966 | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | N/A |
| Unknown | 25OH Vitamin D Overdoses and Risk of Bronchopulmonary Dysplasia or Death NCT05944055 | Hospices Civils de Lyon | — |
| Active Not Recruiting | Cellular Therapy for Extreme Preterm Infants at Risk of Developing Bronchopulmonary Dysplasia NCT04255147 | Ottawa Hospital Research Institute | Phase 1 |
| Completed | Impact of Extended CPAP on Bronchopulmonary Dysplasia NCT05547139 | Christiana Care Health Services | N/A |
| Recruiting | Effects of a Physical Therapy Intervention on Motor Delay in Infants Admitted to a Neonatal Intensive Care Uni NCT05568264 | Shirley Ryan AbilityLab | N/A |
| Recruiting | The Diaphragmatic Initiated Ventilatory Assist (DIVA) Trial NCT05446272 | University of Pennsylvania | N/A |
| Unknown | Towards Life-Long Healthy Lungs: A Multidisciplinary Follow-up Framework for Preterm Infants NCT05618769 | Franciscus Gasthuis | N/A |
| Unknown | Effect of Caffeine Versus Probiotic on Preterm Neonates With Bronchopulmonary Dysplasia NCT05682807 | Tanta University | Phase 3 |
| Terminated | PAL to Improve Oral Feeding for Infants With Chronic Lung Disease NCT05446389 | University of Missouri-Columbia | N/A |
| Completed | Right vEntricular Function Prediction mOdel to Identify pReterm infanTs With Early BronchoPulmonary Dysplasia. NCT05235399 | University Hospital Plymouth NHS Trust | — |
| Completed | Comparison of the Acute Effects of Chest Physiotherapy Methods Applied in Different Positions in Preterm Newbo NCT05036603 | Sanko University | N/A |
| Recruiting | Efficacy Evaluation of UCB-MNCs in the Treatment of Refractory Neonatal Diseases NCT06427642 | Shandong Qilu Stem Cells Engineering Co., Ltd. | N/A |
| Completed | Inhaled Tobramycin in BPD NCT04560179 | Erik Allen Jensen | Phase 1 |
| Completed | Relationship Between Fungal Colonization and Severe Bronchopulmonary Dysplasia NCT05152875 | Centre Hospitalier Sud Francilien | — |
| Unknown | Corticosteroid Use in Premature Babies and Lung Ultrasonografi Use in the Progression to Bronchopulmonary Dysp NCT05621785 | Kırıkkale University | — |
| Unknown | Pulmonary Hypertension in Extremely Preterm Infants NCT05136235 | Universitair Ziekenhuis Brussel | N/A |
| Terminated | Prone Versus Supine Positioning and the Impact on Bronchopulmonary Dysplasia in Very Low Birth Weight Infants. NCT04890158 | Montefiore Medical Center | N/A |
| Unknown | Late Surfactant After a Recruitment Maneuver in Extremely Low Gestational Age Newborns - LATE-REC-SURF Trial NCT04825197 | VENTO GIOVANNI | Phase 2 |
| Withdrawn | Body Weight Growth After Birth and Bronchopulmonary Dysplasia NCT05053269 | Daping Hospital and the Research Institute of Surgery of the Third Military Medical University | — |
| Unknown | Intratracheal Budesonide With Surfactant to Prevent Bronchopulmmonary Dysplasia. NCT04862377 | Hospital Clinic of Barcelona | Phase 3 |
| Completed | The Baby Lung Study NCT05152316 | University College, London | — |
| Terminated | NAVA vs. CMV Crossover in Severe BPD NCT04821453 | Children's Hospital of Philadelphia | N/A |
| Terminated | Maintaining Optimal HVNI Delivery Using Automatic Titration of Oxygen in Preterm Infants NCT05030012 | Vapotherm, Inc. | N/A |
| Completed | A Clinical Safety Study of AT-100 (rhSP-D) in Preterm Neonates at High Risk for Bronchopulmonary Dysplasia (BP NCT04662151 | Airway Therapeutics, Inc. | Phase 1 |
| Completed | CPAP Or Nasal Cannula Oxygen for Preterm Infants: A Randomized Controlled Trial NCT04792099 | University of Alabama at Birmingham | N/A |
| Unknown | Optimal Dose of Surfactant for Preterm Infants With Respiratory Distress Syndrome NCT04984057 | Daping Hospital and the Research Institute of Surgery of the Third Military Medical University | N/A |
| Completed | The Efect of Azithromicyn on Bronchopulmonary Displasia in Extremely Preterm and Very Preterm Infant NCT05311228 | Indonesia University | Phase 4 |
| Unknown | Nasal High-frequency Oscillatory Ventilation (NHFOV) for Ventilated Newborn Infants With BPD NCT04905732 | Daping Hospital and the Research Institute of Surgery of the Third Military Medical University | N/A |
| Recruiting | Reversibility of Bronchial Obstruction in Children Born Preterm NCT06110481 | Charles University, Czech Republic | — |
| Unknown | Treatment of Classic Mid-trimester PPROM by Means of Continuous Amnioinfusion NCT04696003 | Martin-Luther-Universität Halle-Wittenberg | Phase 3 |
| Completed | Comparing Two Different Modes of Ventilation in Pretem Neonates Bilevel VG and PRVC NCT04191239 | Ankara City Hospital Bilkent | — |
| Terminated | Effect of Synchronized vs. Continuous HFNC Using NAVA on WOB in Infants With BPD NCT04274192 | University of Arkansas | N/A |
| Unknown | Multiparametric Bronchopulmonary Prediction NCT04785859 | Andaluz Health Service | — |
| Withdrawn | Hypercapnia and Its Association With Long-term Respiratory Morbidities in Premature Infants With Chronic Lung NCT02996162 | Boston Children's Hospital | — |
| Unknown | Clinic Features and Outcome of BPD (SGBPD) NCT04237844 | Wang Jianhui | — |
| Completed | Complete Shielding of Multivitamins to Reduce Toxic Peroxides in the Parenteral Nutrition: A Pilot Study NCT04234152 | St. Justine's Hospital | N/A |
| Completed | Work of Breathing in Premature Infants at Discharge NCT03682575 | Christiana Care Health Services | — |
| Unknown | The Impact of Lung Recruitment Maneuver in 24-32 Weekers, and the Incidence of Bronchopulmonary Dysplasia NCT04555889 | Dr. R. Adhi Teguh Perma Iskandar, Sp.A(K) | N/A |
| Completed | Ventilation-perfusion (V/Q) Ratio and Alveolar Surface Area in Preterm Infants NCT04936477 | King's College London | N/A |
| Terminated | Safety and Efficacy Outcomes Following Previously Administered Short-Term Treatment With SHP607 in Extremely P NCT04506619 | Oak Hill Bio Ltd | — |
| Unknown | Follow-up Results of Newborns With Tracheostomy NCT04497740 | Hacettepe University | — |
| Unknown | Glucocorticoids and Pulmonary Hypertension NCT04499196 | Washington University School of Medicine | — |
| Unknown | Estimating Length of Endotracheal Tube Insertion Using Gestational Age or Nasal-Tragus Length in Newborn Infan NCT04393337 | Princess Nourah Bint Abdulrahman University | N/A |
| Completed | Exposure to Plasticisers in the Neonatal Intensive Care Unit NCT05404815 | University Hospital, Antwerp | — |
| Unknown | Comparison of Classification Standards of BPD in Premature Infants NCT04184648 | Wang Jianhui | — |
| Unknown | Interest of Pulmonary Ultrasound to Predict Evolution Towards Bronchopulmonary Dysplasia in Premature Infants NCT04209088 | University Hospital, Limoges | N/A |
| Completed | Preservation of Blood in Extremely Preterm Infants NCT04239690 | David Ley | N/A |
| Recruiting | Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Stan NCT04278404 | Duke University | — |
| Recruiting | Forced Oscillometry in Infants With Bronchopulmonary Dysplasia NCT04270045 | Winston Manimtim | — |
| Completed | Epidemiological Study for Bronchopulmonary Dysplasia (BPD) in China NCT03850457 | Children's Hospital of Fudan University | — |
| Completed | Analysis of BPD in Premature Infants With Typical Imaging Changes NCT04163822 | Wang Jianhui | — |
| Unknown | SMOFlipid and Incidence of BPD in Preterm Infants NCT04078906 | University of Calgary | N/A |
| Unknown | Continuous Versus Intermittent Bolus Feeding in Very Preterm Infants - Effect on Respiratory Morbidity NCT03961139 | National University Hospital, Singapore | N/A |
| Withdrawn | Intratracheal Umbilical Cord-derived Mesenchymal Stem Cell for the Treatment of Bronchopulmonary Dysplasia (BP NCT03645525 | Children's Hospital of Fudan University | Phase 1 / Phase 2 |
| Completed | Ultrasound Assessment of Diaphragmatic Function in Infants With BPD NCT04941963 | Mount Sinai Hospital, Canada | — |
| Unknown | Budesonide With Intratracheal Surfactants in Extremely Preterm Infants NCT04019106 | University of Manitoba | Phase 1 / Phase 2 |
| Terminated | A Safety Study of IV Stem Cell-derived Extracellular Vesicles (UNEX-42) in Preterm Neonates at High Risk for B NCT03857841 | United Therapeutics | Phase 1 |
| Unknown | Zinc Supplementation on Very Low Birth Weight Infant NCT04050488 | Fakultas Kedokteran Universitas Indonesia | Phase 4 |
| Terminated | L-citrulline and Pulmonary Hypertension Associated With Bronchopulmonary Dysplasia NCT03542812 | University of Utah | EARLY_Phase 1 |
| Unknown | Indoor Air Quality and Respiratory Morbidity in School-Aged Children With BPD NCT04107701 | Boston Children's Hospital | — |
| Terminated | Inhaled Nitric Oxide for Pulmonary Hypertension and Bronchopulmonary Dysplasia NCT03576885 | AdventHealth | Phase 1 / Phase 2 |
| Active Not Recruiting | Follow-up Study of Safety and Efficacy in Subjects Who Completed PNEUMOSTEM® Phase II (MP-CR-012) Clinical Tri NCT04003857 | Medipost Co Ltd. | Phase 2 |
| Completed | Intratracheal Budesonide/Surfactant Prevents BPD NCT03275415 | Taipei Medical University | Phase 4 |
| Unknown | Human Mesenchymal Stem Cells For Moderate and Severe Bronchopulmonary Dysplasia NCT03601416 | Children's Hospital of Chongqing Medical University | Phase 2 |
| Recruiting | A Clinical Efficacy and Safety Study of OHB-607 in Preventing Bronchopulmonary Dysplasia in Extremely Prematur NCT03253263 | OHB Neonatology Ltd. | Phase 2 |
| Recruiting | Genesis Electrical Impedance Tomography (EIT): A Preliminary Study NCT03797183 | University of Colorado, Denver | — |
| Completed | Mesenchymal Stem Cell Therapy for Bronchopulmonary Dysplasia in Preterm Babies NCT02443961 | Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal | Phase 1 |
| Active Not Recruiting | Early Prediction of Spontaneous Patent Ductus Arteriosus (PDA) Closure and PDA-Associated Outcomes NCT03782610 | Nationwide Children's Hospital | — |
| Completed | Umbilical Cord Mesenchymal Stem Cells Transplantation in the Treatment of Bronchopulmonary Dysplasia NCT04062136 | Vinmec Research Institute of Stem Cell and Gene Technology | Phase 1 |
| Unknown | Human Mesenchymal Stem Cells For Infants At High Risk For Bronchopulmonary Dysplasia NCT03774537 | Children's Hospital of Chongqing Medical University | Phase 1 / Phase 2 |
| Completed | Systemic Management in Extremely Preterm and Extremely Low Birth Weight Infants NCT06082414 | Peking University | — |
| Unknown | Effects of Fat-soluble Vitamins Supplementation on Common Complications and Neural Development in Very Low Bir NCT03876704 | First Affiliated Hospital Xi'an Jiaotong University | Phase 3 |
| Withdrawn | Inhaled Budesonide for Non-ventilated Infants at High Risk of Bronchopulmonary Dysplasia: the i-BUD Pilot Stud NCT01895075 | Dr. Michael Dunn | Phase 2 |
| Completed | Thrombocytopoiesis and Platelet Homeostasis in Infants With Bronchoplumonary Dysplasia NCT04348799 | yangjie | — |
| Active Not Recruiting | A Cohort Study of the Intestinal Microbiota of Premature Infants NCT03717584 | University of California, Davis | — |
| Terminated | Randomized Controlled Trial to Evaluate the Safety and Efficacy of Acetaminophen in Preterm Infants Used in Co NCT03701074 | University of South Alabama | Phase 2 |
| Unknown | Invasive Ventilation Strategies for Neonates With Acute Respiratory Distress Syndrome Syndrome (ARDS) NCT03372525 | Daping Hospital and the Research Institute of Surgery of the Third Military Medical University | N/A |
| Recruiting | Mesenchymal Stem Cells for Prevention of Bronchopulmonary Dysplasia in Infants NCT03631420 | Meridigen Biotech Co., Ltd. | Phase 1 |
| Completed | The Effect of Surfactant Dose on Outcomes in Preterm Infants With RDS NCT03808402 | Chiesi UK | — |
| Unknown | Hydrotherapy in Premature Infants With Bronchopulmonary Dysplasia NCT03538977 | Universidade Estadual de Londrina | N/A |
| Completed | Enteral L Citrulline Supplementation in Preterm Infants - Safety, Efficacy and Dosing NCT03649932 | The University of Texas Medical Branch, Galveston | Phase 1 |
| Terminated | MRI of Lung Structure and Function in Preterm Children NCT03475264 | The Hospital for Sick Children | — |
| Completed | Autologous Cord Blood Mononuclear Cells for Bronchopulmonary Dysplasia in Very Preterm Neonates NCT02999373 | Guangdong Women and Children Hospital | Phase 2 |
| Unknown | Follow-Up Study of Mesenchymal Stem Cells for Bronchopulmonary Dysplasia NCT03873506 | Children's Hospital of Chongqing Medical University | Phase 1 |
| Unknown | Human Mesenchymal Stem Cells For Bronchopulmonary Dysplasia NCT03558334 | Children's Hospital of Chongqing Medical University | Phase 1 |
| Completed | BPD Saturation TARgeting NCT03385330 | Children's Hospital of Philadelphia | N/A |
| Unknown | Non-invasive Respiratory Support in Preterm Infants NCT03512158 | McMaster Children's Hospital | N/A |
| Recruiting | MRI in BPD Subjects NCT03657693 | Children's Hospital Medical Center, Cincinnati | — |
| Recruiting | Exploring the Utility of Hyperpolarized 129Xe MRI in Healthy Volunteers and Patients With Lung Disease NCT03455686 | McMaster University | N/A |
| Completed | Safety of Sildenafil in Premature Infants NCT03142568 | University of North Carolina, Chapel Hill | Phase 2 |
| Terminated | Enteral Zinc to Improve Growth in Infants at Risk for Bronchopulmonary Dysplasia NCT03532555 | University of Utah | N/A |
| Unknown | p16Ink4a in Bronchopulmonary Dysplasia in Children NCT03540680 | Centre Hospitalier Intercommunal Creteil | N/A |
| Completed | Pulmonary MRI of Ex-preterm Children With and Without BPD To Understand Risk of Emphysematous Changes NCT02921308 | Children's Hospital of Eastern Ontario | — |
| Completed | The Effects of Position on the Oxygenation Instability of Premature Infants as Documented by SpO2 Histograms NCT03546543 | Rambam Health Care Campus | N/A |
| Unknown | Prediction for Bronchopulmonary Dysplasia NCT05181319 | Kai Mu | — |
| Unknown | Efficacy of Adding Budesonide to Poractant Alfa to Prevent Bronchopulmonary Dysplasia. NCT03521063 | Hospital Central "Dr. Ignacio Morones Prieto" | Phase 4 |
| Active Not Recruiting | Pulmonary Function Using Non-invasive Forced Oscillometry NCT03346343 | University of Alabama at Birmingham | N/A |
| Withdrawn | Stem Cells for Bronchopulmonary Dysplasia NCT03378063 | Daping Hospital and the Research Institute of Surgery of the Third Military Medical University | EARLY_Phase 1 |
| Completed | Mid and Standard Frequency Ventilation in Infants With Respiratory Distress Syndrome NCT03231735 | University of Alabama at Birmingham | Phase 2 / Phase 3 |
| Completed | Gastrointestinal Microbiome Influence on the Development of Bronchopulmonary Dysplasia NCT03229967 | University of Tennessee | — |
| Completed | MISA to NRDS：a Multicenter Study in China NCT04077333 | Peking University Third Hospital | N/A |
| Completed | Fluid Filled Lung Oxygenation Assistance Trial NCT03041740 | Children's Hospital of Philadelphia | Phase 1 |
| Completed | A Study of Tobacco Smoke and Children With Respiratory Illnesses NCT03062709 | MaineHealth | N/A |
| Unknown | Study to Justify Steroid Use in Preterm Neonates to Prevent Bronchopulmonary Dysplasia NCT03035214 | Maadi Military Hospital | Phase 2 |
| Completed | Antibiotic "Dysbiosis" in Preterm Infants NCT02784821 | University of Florida | Phase 2 |
| Completed | GER Poses a Potential Risk for Late Complications of BPD NCT03014453 | Shengjing Hospital | — |
| Completed | Neurally Adjusted Ventilatory Assist vs Proportional Assist Ventilation NCT02967549 | King's College London | N/A |
| Completed | Work of Breathing During Non-invasive Ventilation in Premature Neonates NCT02788110 | Arkansas Children's Hospital Research Institute | N/A |
| Completed | Neolifes Heart - Pulmonary Hypertension in Preterm Children NCT02729844 | University Medical Center Groningen | — |
| Completed | Pulmonary Outcomes of Bronchopulmonary Dysplasia in Young Adulthood NCT02820818 | St. Justine's Hospital | — |
| Completed | Bronchopulmonary Dysplasia: From Neonatal Chronic Lung Disease to Early Onset Adult COPD NCT02723513 | Western University, Canada | N/A |
| Completed | The Role of Transthoracic Echocardiography in Diagnosis of Pulmonary Hypertension of Infants With Bronchopulmo NCT05082272 | Kayseri City Hospital | — |
| Completed | Safety of Furosemide in Premature Infants at Risk of Bronchopulmonary Dysplasia (BPD) NCT02527798 | University of North Carolina, Chapel Hill | Phase 2 |
| Terminated | Early Versus Late Caffeine for ELBW Newborns NCT02524249 | Wayne State University | N/A |
| Unknown | Impact of an Exercise Program for Children Aged 4 to 6 Years With Bronchopulmonary Dysplasia NCT02523521 | Hospital de Nens de Barcelona | N/A |
| Active Not Recruiting | Maternal Omega-3 Supplementation to Reduce Bronchopulmonary Dysplasia NCT02371460 | CHU de Quebec-Universite Laval | Phase 3 |
| Completed | Use of Human Milk Cream to Decrease Length of Stay in Extremely Premature Infants NCT02475434 | Baylor College of Medicine | N/A |
| Completed | Safety and Efficacy of PNEUMOSTEM® in Premature Infants at High Risk for Bronchopulmonary Dysplasia (BPD) - a NCT02381366 | Medipost, Inc. | Phase 1 / Phase 2 |
| Withdrawn | TINN2: Treat Infection in NeoNates 2 NCT02282176 | Institut National de la Santé Et de la Recherche Médicale, France | Phase 3 |
| Completed | Transpyloric Feeding in Severe Bronchopulmonary Dysplasia NCT02142621 | Children's Hospital of Philadelphia | N/A |
| Completed | Neurotrophin Expression in Infants as a Predictor of Respiratory and Neurodevelopmental Outcomes NCT03373539 | The Cleveland Clinic | — |
| Completed | Duration of Continuous Positive Airway Pressure and Pulmonary Function Testing in Preterm Infants NCT02249143 | Oregon Health and Science University | N/A |
| Completed | Seattle-PAP Bubble Nasal CPAP and Work of Breathing NCT02210026 | Seattle Children's Hospital | Phase 1 |
| Unknown | High Frequency Oscillatory Ventilation Combined With Intermittent Sigh Breaths: Effects on Blood Oxygenation a NCT01959009 | Rigshospitalet, Denmark | N/A |
| Completed | Continuous Positive Airway Pressure Via Binasal Prong vs Nasal Mask: a Randomised Controlled Trial NCT02287116 | Zekai Tahir Burak Women's Health Research and Education Hospital | N/A |
| Completed | Oral Vitamin A Supplementation in Neonates With Birth Weight < 1500 g NCT02102711 | Francesca Garofoli | N/A |
| Completed | Long-term Safety and Efficacy Follow-up Study of PNEUMOSTEM® in Patients Who Completed PNEUMOSTEM® Phase-I Stu NCT02023788 | Medipost Co Ltd. | — |
| Completed | Effective Approaches & Strategies to Ease Off Nasal CPAP In Preterm Infants NCT02819050 | Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center | N/A |
| Completed | Follow-up Safety and Efficacy Evaluation on Subjects Who Completed PNEUMOSTEM® Phase-II Clinical Trial NCT01897987 | Medipost Co Ltd. | N/A |
| Completed | High Frequency Oscillatory Ventilation Combined With Intermittent Sigh Breaths: Effects on Lung Volume Monitor NCT01962818 | Rigshospitalet, Denmark | N/A |
| Completed | Biomarkers and Volumetric Capnography in BPD NCT02083562 | University Hospital, Basel, Switzerland | — |
| Unknown | Nasal Mask and Prong Use in Non-invasive Ventilation for Newborns NCT01989442 | Ankara University | N/A |
| Completed | Preterm Infant Inhaled Albuterol Dosing NCT02447250 | Oregon Health and Science University | Phase 4 |
| Completed | Efficacy of Recombinant Human Clara Cell 10 Protein (rhCC10) Administered to Premature Neonates With Respirato NCT01941745 | Tufts Medical Center | Phase 2 |
| Completed | Tidal Neonatal NO, Vitamins A and D, and Infant Lung Disease - The AD-ON Study NCT01722760 | Hillerod Hospital, Denmark | — |
| Completed | Genes Associated With Bronchopulmonary Dysplasia and Retinopathy of Prematurity NCT01780155 | National Institute of Environmental Health Sciences (NIEHS) | — |
| Completed | Assessment of Lung Aeration at Birth NCT01739114 | University of Alberta | N/A |
| Completed | Efficacy and Safety Evaluation of Pneumostem® Versus a Control Group for Treatment of BPD in Premature Infants NCT01828957 | Medipost Co Ltd. | Phase 2 |
| Terminated | Study of Inhaled Nitric Oxide (iNO) and Respiratory Outcomes in Late Preterm Infants NCT01748045 | Tufts Medical Center | Phase 2 / Phase 3 |
| Completed | Outcome of Extremely Preterm Infants Who Received Systemic Postnatal Corticosteroid for Bronchopulmonary Dyspl NCT05055193 | Hospices Civils de Lyon | — |
| Unknown | Determining the Effect of Spironolactone on Electrolyte Supplementation in Preterm Infants With Chronic Lung D NCT01721655 | West Virginia University Healthcare | Phase 2 / Phase 3 |
| Completed | Azithromycin in the Prevention of Lung Injury in Premature Newborn NCT03485703 | Hospital de Clinicas de Porto Alegre | Phase 4 |
| Completed | Consequences of Antiangiogenic Factors Involved in Preeclampsia on Intra-uterine Growth Restricted Preterm New NCT01648855 | Assistance Publique - Hôpitaux de Paris | — |
| Completed | Vitamin D Supplementation for Extremely Preterm Infants NCT01600430 | University of Alabama at Birmingham | Phase 2 / Phase 3 |
| Completed | Prospective Study on Plasma Pro-endothelin-1 in Predicting Bronchopulmonary Dysplasia NCT01644981 | University of Zurich | — |
| Completed | Gastrin-Releasing Peptide and Bronchopulmonary Dysplasia NCT01748565 | Duke University | — |
| Completed | Respiratory Management of Preterm Infants and Bronchopulmonary Dysplasia NCT03411018 | Manuel Sanchez Luna | — |
| Unknown | OPTIMIST-A Trial: Minimally-invasive Surfactant Therapy in Preterm Infants 25-28 Weeks Gestation on CPAP NCT02140580 | Menzies Institute for Medical Research | Phase 4 |
| Completed | The Efficacy and Safety of Montelukast Sodium in the Prevention of Bronchopulmonary Dysplasia NCT01717625 | Ajou University School of Medicine | Phase 2 |
| Unknown | Clarithromycin Prophylaxis in Preterm Infants Colonisation With Ureaplasma Urealyticum and Mycoplasma Hominis NCT01652118 | Zekai Tahir Burak Women's Health Research and Education Hospital | Phase 3 |
| Completed | Respiratory Outcome at Adolescence of Very Low Birthweight Infants NCT01424553 | Assistance Publique - Hôpitaux de Paris | N/A |
| Active Not Recruiting | Follow-Up Study of Safety and Efficacy of Pneumostem® in Premature Infants With Bronchopulmonary Dysplasia NCT01632475 | Samsung Medical Center | — |
| Completed | Improving Prematurity-Related Respiratory Outcomes at Vanderbilt NCT01460576 | Vanderbilt University Medical Center | — |
| Completed | Hydrocortisone for BPD NCT01353313 | NICHD Neonatal Research Network | Phase 3 |
| Completed | Functional and Lymphocytic Markers of Respiratory Morbidity in Hyperoxic Preemies NCT01607216 | University of Rochester | — |
| Unknown | Inhaled Extra-fine Hydrofluoalkane-beclomethasone (QVAR) in Premature Infants With Bronchopulmonary Dysplasia NCT01373008 | Bnai Zion Medical Center | Phase 2 |
| Completed | Safety and Efficacy Evaluation of PNEUMOSTEM® Treatment in Premature Infants With Bronchopulmonary Dysplasia NCT01297205 | Medipost Co Ltd. | Phase 1 |
| Unknown | Surfactant Administration During Spontaneous Breathing NCT01329432 | Zekai Tahir Burak Women's Health Research and Education Hospital | Phase 4 |
| Unknown | Autologous Cord Blood Infusion for the Prevention and Treatment of Prematurity Complications In Preterm Neonat NCT02050971 | Pomeranian Medical University Szczecin | Phase 1 |
| Completed | Ascorbyl Peroxide Association With Bronchopulmonary Dysplasia NCT01439295 | St. Justine's Hospital | — |
| Unknown | Intratracheal Umbilical Cord-derived Mesenchymal Stem Cells for Severe Bronchopulmonary Dysplasia NCT01207869 | China Medical University Hospital | Phase 1 |
| Unknown | Pilot Study of Topical Steroid for Prevention of Chronic Lung Disease in Extremely Premature Infants. NCT01268215 | East Carolina University | Phase 2 |
| Completed | Efficacy and Safety of Inhaled Budesonide in Very Preterm Infants at Risk for Bronchopulmonary Dysplasia NCT01035190 | University Children's Hospital Tuebingen | Phase 3 |
| Completed | Trial of Late Surfactant for Prevention of Bronchopulmonary Dysplasia NCT01022580 | Roberta Ballard | Phase 3 |
| Completed | Exogenous Surfactant in Very Preterm Neonates in Prevention of Bronchopulmonary Dysplasia NCT01039285 | Jean Michel Hascoet | Phase 4 |
| Completed | Palivizumab for Prevention of Severe Respiratory Syncytial Virus Infection in Russian Children NCT01006629 | Abbott | Phase 2 / Phase 3 |
| Completed | Inhaled Nitric Oxide (INO) for the Prevention of Bronchopulmonary Dysplasia (BPD) in Preterm Infants NCT00931632 | Mallinckrodt | Phase 3 |
| Completed | The Role of Anti-Reflux Surgery for Gastroesophageal Reflux Disease in Premature Infants With Bronchopulmonary NCT00926276 | The University of Texas Health Science Center, Houston | Phase 4 |
| Unknown | Genetic Susceptibility for Bronchopulmonary Dysplasia in Preterm Infants NCT00904774 | Centre Hospitalier Intercommunal Creteil | — |
| Withdrawn | Phase 1 Intravenous Citrulline for the Prevention of Bronchopulmonary Dysplasia in Preterm Infants NCT00742534 | Vanderbilt University | Phase 1 |
| Terminated | Inhaled Nitric Oxide and Neuroprotection in Premature Infants NCT00515281 | University of Chicago | Phase 2 / Phase 3 |
| Completed | PREMILOC Trial to Prevent Bronchopulmonary Dysplasia in Very Preterm Neonates NCT00623740 | Assistance Publique - Hôpitaux de Paris | Phase 3 |
| Completed | NCPAP + Heliox as a Treatment for Infant Respiratory Distress Syndrome (RDS) NCT01383850 | Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico | Phase 2 |
| Completed | Trial of Late Surfactant to Prevent BPD: A Pilot Study in Ventilated Preterm Neonates Receiving Inhaled Nitric NCT00569530 | Roberta Ballard | Phase 3 |
| Completed | Study of Nasal Ventilation In Preterm Infants To Decrease Time on The Respirator NCT01440647 | Women and Infants Hospital of Rhode Island | N/A |
| Completed | Montelukast in Very Low Birthweight Infants NCT00492102 | Children's Hospital Medical Center, Cincinnati | Phase 1 |
| Completed | Examining the Use of Non-Invasive Inhaled Nitric Oxide to Reduce Chronic Lung Disease in Premature Newborns NCT00955487 | University of Colorado, Denver | Phase 2 |
| Completed | Assessment of Lung Structure and Function of Infants Born Prematurely NCT00422305 | Indiana University School of Medicine | — |
| Completed | Early NCPAP Before Surfactant Treatment in Very Preterm Infants With RDS NCT01996670 | Xiangya Hospital of Central South University | — |
| Completed | Growth of Airways and Lung Tissues in Premature and Healthy Infants NCT00419588 | Indiana University | — |
| Unknown | Cysteine Supplementation in Critically Ill Neonates NCT00254176 | University of California, Los Angeles | Phase 2 / Phase 3 |
| Terminated | A Trial of Infant Flow Biphasic Nasal Continuous Airway Pressure (NCPAP) Versus Infant Flow NCPAP for the Faci NCT00308789 | Mount Sinai Hospital, Canada | Phase 2 |
| Completed | Neonatal Intensive Care (NICU) Course and Hospital Outcome of Infants With BPD Treated Using Inhaled Nitric Ox NCT00757146 | University of Utah | — |
| Terminated | Probiotics for the Prevention of Premature Birth and Neonatal Related Morbidity NCT00303082 | Oswaldo Cruz Foundation | Phase 3 |
| Completed | Randomized Trial of Hydrocortisone in Very Preterm High-Risk Infants NCT00167544 | Nationwide Children's Hospital | Phase 2 |
| Terminated | Management of Hyponatremia in Preterm Infants on Diuretics NCT00156572 | The University of Texas Health Science Center, Houston | Phase 3 |
| Completed | Appropriate Oxygen Levels for Extremely Preterm Infants: a Prospective Meta-analysis NCT01124331 | University of Sydney | N/A |
| Completed | Surfactant Positive Airway Pressure and Pulse Oximetry Trial NCT00233324 | NICHD Neonatal Research Network | Phase 3 |
| Terminated | SURFAXIN® Treatment for Prevention of Bronchopulmonary Dysplasia (BPD) in Very Low Birth Weight (VLBW) Infants NCT00215540 | Windtree Therapeutics | Phase 2 |
| Completed | Randomized Trial of Nasal Continuous Positive Airway Pressure or Synchronized Nasal Ventilation in Premature I NCT00188968 | University of Manitoba | Phase 3 |
| Completed | Pilot Trial of Surfactant Booster Prophylaxis For Ventilated Preterm Neonates NCT00208039 | Children's Hospital of Philadelphia | N/A |
| Completed | Trial II of Lung Protection With Azithromycin in the Preterm Infant NCT00319956 | Hubert Ballard | Phase 2 |
| Completed | Assessment of the Pulmonary Diffusion Capacity in Healthy Infants and Infants With Chronic Lung Disease NCT00428038 | Indiana University | — |
| Completed | Effects of Delayed Cord Clamping in Very Low Birth Weight Infants NCT00840983 | University of Rhode Island | Phase 1 |
| Completed | Prolonged Outcomes After Nitric Oxide (PrONOx) NCT00234247 | University of Pittsburgh | — |
| Completed | Delivery Room CPAP in Extremely Low Birth Weight Infants NCT01223274 | NICHD Neonatal Research Network | Phase 1 / Phase 2 |
| Completed | Inhaled Corticosteroids for Treatment of Bronchopulmonary Dysplasia NCT03503994 | Mount Sinai Hospital, Canada | N/A |
| Completed | Inhaled Nitric Oxide for Preventing Chronic Lung Disease in Premature Infants NCT00006401 | University of Colorado, Denver | Phase 3 |
| Completed | Inhaled NO in Prevention of Chronic Lung Disease NCT00000548 | University of California, San Francisco | Phase 3 |
| Completed | Safety, Pk and Anti-inflammatory Effects of CC10 Protein in Premature Infants With Respiratory Distress Syndro NCT01473264 | Clarassance, Inc. | Phase 1 / Phase 2 |
| Terminated | Minimal Breathing Support and Early Steroids to Prevent Chronic Lung Disease in Extremely Premature Infants (S NCT00005777 | NICHD Neonatal Research Network | Phase 3 |
| Completed | Study of the Pathobiology of Bronchopulmonary Dysplasia in Newborns NCT00006058 | National Center for Research Resources (NCRR) | — |
| Completed | Phase II Pilot Study of Early Cortisol Replacement to Prevent Bronchopulmonary Dysplasia NCT00004669 | National Center for Research Resources (NCRR) | Phase 2 |
| Completed | Post-hospitalization Nursing Effectiveness (PHONE) Study NCT00314431 | Wake Forest University | Phase 3 |
| Completed | Vitamin A Supplementation for Extremely-Low-Birth-Weight Infants NCT01203488 | NICHD Neonatal Research Network | Phase 1 / Phase 2 |
| Completed | Phase III Randomized, Double-Blind Study of Dexamethasone Vs Dexamethasone/Methylprednisolone Vs Placebo for B NCT00004785 | National Center for Research Resources (NCRR) | Phase 3 |
| Completed | Premature Birth and Its Sequelae in Women NCT00005376 | National Heart, Lung, and Blood Institute (NHLBI) | — |
| Completed | Inhaled Beclomethasone to Prevent Chronic Lung Disease NCT00000576 | National Heart, Lung, and Blood Institute (NHLBI) | Phase 3 |
| Completed | Dexamethasone Therapy in VLBW Infants at Risk of CLD NCT00011362 | NICHD Neonatal Research Network | Phase 3 |
| Completed | Study of the Effect of Four Methods of Cardiopulmonary Resuscitation Instruction on Psychosocial Response of P NCT00004805 | National Center for Research Resources (NCRR) | N/A |
| Completed | Exosurf Neonatal and Survanta for Treatment of Respiratory Distress Syndrome NCT01203358 | NICHD Neonatal Research Network | Phase 2 / Phase 3 |
| Completed | Developmental Sequelae of Severe Chronic Lung Disorders NCT00005294 | National Heart, Lung, and Blood Institute (NHLBI) | — |
| Completed | Antecedents of Bronchopulmonary Dysplasia NCT00005293 | National Heart, Lung, and Blood Institute (NHLBI) | — |
| Completed | Risk Factors in Bronchopulmonary Dysplasia (Newborn Lung Project) NCT00005289 | University of Wisconsin, Madison | — |
| Completed | Clinical Interventions in Respiratory Distress Syndrome and Neonatal Lung Injury - SCOR in Lung Biology and Di NCT00005683 | University of Rochester | — |
| Completed | Late Sequelae of Bronchopulmonary Dysplasia NCT00005287 | Stanford University | — |
| Completed | High Frequency Ventilation in Premature Infants (HIFI) NCT00000567 | National Heart, Lung, and Blood Institute (NHLBI) | Phase 3 |