NCT03411018

Respiratory Management of Preterm Infants and Bronchopulmonary Dysplasia

The Impact of Modifications on Respiratory Management of Preterm Infants on the Death or Bronchopulmonary Dysplasia Outcome

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 600 (actual)
• Sponsor: Manuel Sanchez Luna · Academic / Other
• Sex: All
• Age: 36 Weeks
• Healthy volunteers: Not accepted

Summary

This observational study evaluates the impact of respiratory management modifications implemented in our institution on the intubation rates and the death or Bronchopulmonary Dysplasia (BPD) outcome.

Detailed description

Less invasive respiratory management has been implemented in most neonatal units as well as lung protective ventilatory strategies when intubation is required in order to minimize ventilator induced lung injury. In our institution a new ventilatory protocol including less invasive surfactant administration, Synchronized nasal positive pressure ventilation and early rescue High frequency ventilation has been implemented during 2013-14. Hypothesis: New less invasive and lung protective strategies to prevent lung injury had been effective in reducing intubation rates.

Conditions

• Bronchopulmonary Dysplasia

Interventions

Type	Name	Description
OTHER	Mechanical ventilation exposure

Timeline

• Start date: 2012-01-01
• Primary completion: 2017-12-31
• Completion: 2017-12-31
• First posted: 2018-01-25
• Last updated: 2021-08-27

Locations

1 site across 1 country: Spain