Trials / Unknown
UnknownNCT04499196
Glucocorticoids and Pulmonary Hypertension
Prospective Study of Glucocorticoids as a Mechanism to Treat Pulmonary Hypertension
- Status
- Unknown
- Phase
- —
- Study type
- Observational
- Enrollment
- 40 (estimated)
- Sponsor
- Washington University School of Medicine · Academic / Other
- Sex
- All
- Age
- 1 Day – 5 Years
- Healthy volunteers
- Not accepted
Summary
Pediatric idiopathic pulmonary hypertension has significant morbidity and mortality. An ever expanding body of knowledge indicates the important contribution of inflammation to pathogenesis and successful treatment with glucocorticoids. Over the last several years the investigators have utilized steroids in patients with severe pulmonary hypertension as part of a treatment regimen. These basic science studies possibly identifies a biochemical etiology for the development of disease and may also be impacted by the administration of steroids. Additionally, there is a commercially available assay which tests for all of the above molecules.
Conditions
- Pulmonary Hypertension Due to Lung Diseases and Hypoxia
- Pulmonary Hypertension
- Bronchopulmonary Dysplasia
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | GlucoCorticoid | Administering glucocorticoid |
Timeline
- Start date
- 2020-07-29
- Primary completion
- 2022-07-29
- Completion
- 2022-07-29
- First posted
- 2020-08-05
- Last updated
- 2022-03-31
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT04499196. Inclusion in this directory is not an endorsement.