NCT02820818

Pulmonary Outcomes of Bronchopulmonary Dysplasia in Young Adulthood

Bronchopulmonary Dysplasia: From Neonatal Chronic Lung Disease to Early Onset Adult COPD

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 50 (estimated)
• Sponsor: St. Justine's Hospital · Academic / Other
• Sex: All
• Age: 20 Years – 29 Years
• Healthy volunteers: Accepted

Summary

Preterm birth alters the normal sequence of lung development with lasting respiratory consequences. It is still unclear whether observed respiratory morbidities in preterm born individuals reflect sequelae from a non-progressive lung disease that occurred early in life or result from ongoing active disease that, if left undiagnosed and untreated, could increase the risk of a COPD-like phenotype. We propose to examine micro-structural abnormalities of the lung using innovative non-invasive imaging technologies in relation to pulmonary function and markers of inflammation and oxidative stress in young adults born preterm.

Conditions

• Premature Birth
• Obstructive Lung Disease
• Bronchopulmonary Dysplasia

Timeline

• Start date: 2016-06-01
• Primary completion: 2017-04-01
• Completion: 2021-12-01
• First posted: 2016-07-01
• Last updated: 2024-04-10