NCT01424553

Respiratory Outcome at Adolescence of Very Low Birthweight Infants

Respiratory Outcome at Adolescence of Very Low Birthweight Infants : the EPIPAGE Cohort

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 355 (actual)
• Sponsor: Assistance Publique - Hôpitaux de Paris · Academic / Other
• Sex: All
• Age: 14 Years – 15 Years
• Healthy volunteers: Not accepted

Summary

EPIPAGEADO is an observational study. Respiratory symptoms and lung function will be evaluated in very low birth weight and term infants, born in 1997 and included in the French EPIPAGE cohort.

Detailed description

EPIPAGEADO is a multicenter observational study:- to evaluate respiratory symptoms and lung function at adolescence in very low birthweight (VLBW) children, to identify perinatal risk factors for persistent symptoms or impaired lung function tests at adolescence, to assess the exercise tolerance in VLBW children and to search for genetic susceptibility markers associated to impaired lung function. The main criteria for analysis will be the forced expiratory volume in one seconde (FEV1) The study duration will be 36 months the number of centers will be 4 centers in France (Paris-Necker, Nantes, Lille, Rouen) The number of patients to be included will be 400, including 260 VLBW children without BPD, 40 VLBW children with BPD, 100 control children with birth at term.

Conditions

• Premature Baby 26 to 32 Weeks
• Bronchopulmonary Dysplasia

Interventions

Type	Name	Description
OTHER	Prevention and follow-up of the patients pulmonary parameters	Respiratory symptoms and lung function will be evaluated in very low birth weight and term infants, born in 1997 and included in the French EPIPAGE cohort.

Timeline

• Start date: 2011-10-01
• Primary completion: 2014-11-01
• Completion: 2015-04-01
• First posted: 2011-08-29
• Last updated: 2025-09-08

Locations

1 site across 1 country: France