NCT05682807

Effect of Caffeine Versus Probiotic on Preterm Neonates With Bronchopulmonary Dysplasia

Caffeine Versus Probiotic as Adjuvant Therapy for Preterm Neonates With Bronchopulmonary Dysplasia

• Status: Unknown
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 90 (estimated)
• Sponsor: Tanta University · Academic / Other
• Sex: All
• Age: 0 Weeks – 37 Weeks
• Healthy volunteers: Not accepted

Summary

The aim of this study is to evaluate the effectiveness of caffeine versus probiotics supplementation as adjuvant therapy for preterm neonates with Bronchopulmonary dysplasia (BPD).

Conditions

• Bronchopulmonary Dysplasia

Interventions

Type	Name	Description
DRUG	Caffeine	5-10 mg/kg/day IV maintenance dose given after 24 h for 2 months.
DRUG	Probiotic Formula	probiotics sachets supplementation orally, in the form of lyophilized lactic acid bacteria each Aluminium stick pack contains 100 mg ( Meyer et al., 2020) Probio Tec BB12-Blend 30- IF\* (SANDOZ®.) mixed with 10 ml sterile water and given by Ryle tube once daily until discharge from the unit after clinical and laboratory improvement after two months.

Timeline

• Start date: 2022-06-30
• Primary completion: 2024-06-01
• Completion: 2025-06-01
• First posted: 2023-01-12
• Last updated: 2023-01-12

Locations

1 site across 1 country: Egypt