NCT02249143

Duration of Continuous Positive Airway Pressure and Pulmonary Function Testing in Preterm Infants

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 50 (actual)
• Sponsor: Oregon Health and Science University · Academic / Other
• Sex: All
• Age: 1 Year
• Healthy volunteers: Not accepted

Summary

The primary aim of this study is to quantify and compare changes in lung volumes (as measured by functional residual capacity) in premature infants stable on continuous positive airway pressure (CPAP), and then randomized to two additional weeks of CPAP and room air versus room air alone. We hypothesize that infants randomized to additional CPAP will demonstrate an increased functional residual capacity (at the end of the two week study period and prior to discharge) compared to those randomized to room air.

Conditions

• Respiratory Distress Syndrome
• Bronchopulmonary Dysplasia

Interventions

Type	Name	Description
DEVICE	CPAP and room air	Stable premature infants on CPAP and room air and meeting specific stability criteria will be randomized to stay on continuous positive airway pressure and room air for an additional two weeks or will be transitioned to room air alone.

Timeline

• Start date: 2014-09-01
• Primary completion: 2016-05-01
• Completion: 2017-09-01
• First posted: 2014-09-25
• Last updated: 2019-08-29
• Results posted: 2018-11-15

Locations

1 site across 1 country: United States