| Not Yet Recruiting | Percutaneous Cryoablation of Intercostal Nerves for the Treatment of Rib Fractures NCT06533904 | Loma Linda University | N/A |
| Not Yet Recruiting | Nebulized Furosemide, Heparin, Hypertonic Saline in Mechanically Ventilated Acute Respiratory Distress Syndrom NCT07286409 | Tanta University | N/A |
| Recruiting | Effect of L-Carnitine Supplementation in Preterm Neonates NCT07437391 | Muhammad Aamir Latif | N/A |
| Recruiting | LUng and Cardiac Ultrasound for REspiratory Distress in ElDerly NCT06807983 | University Hospital, Toulouse | N/A |
| Recruiting | Safety and Efficacy of APC-0101 in Preterm Infants With Respiratory Distress Syndrome NCT06776783 | Aerogen Pharma Limited | Phase 3 |
| Not Yet Recruiting | Post-extubation Use RAM Cannula Versus Short Binasal Prong Interfaces in Preterm Infants NCT07113535 | Ministry of Health, Saudi Arabia | N/A |
| Recruiting | Endocan and Copeptin Serum Levels in Preterm Neonates With Respiratory Distress Syndrome NCT07154134 | Tanta University | — |
| Completed | Non-Invasive High-Frequency Oscillatory Ventilation vs Conventional Ventilation for Preterm Neonates. NCT07307079 | Muhammad Aamir Latif | N/A |
| Completed | Vojta Reflex Versus Lung Squeezing Technique in Respiratory Distress Preterm Neonate NCT06992492 | Beni-Suef University | N/A |
| Recruiting | Respiratory Distress and Elective Cesarean Section at Term NCT06874478 | Assiut University | — |
| Suspended | Safety and Effectiveness of Placental Derived Exosomes and Umbilical Cord Mesenchymal Stem Cells in Moderate t NCT05387278 | Vitti Labs, LLC | Phase 1 |
| Not Yet Recruiting | MRG-001 as an Immunoregulatory and Regenerative Therapy for ARDS Patients NCT06308926 | MedRegen LLC | Phase 2 |
| Not Yet Recruiting | Post-extubation Pressures in Preterm Neonates: A CER Study NCT06552455 | McMaster Children's Hospital | — |
| Recruiting | Study on Safety and Efficacy of Two Doses of PRS CK STORM in the Modulation of the Cytokine Storm for the Trea NCT06684379 | PEACHES BIOTECH | Phase 1 / Phase 2 |
| Completed | Prehospital Telemedicine Feasibility/Acceptability Pilot NCT05967624 | Boston Medical Center | N/A |
| Recruiting | Personalized Ventilation Based on Ventilation-perfusion Mismatch and Lung Recruitability NCT06430554 | Zhongda Hospital | — |
| Not Yet Recruiting | Less Invasive Surfactant Administration in Late Preterm or Early Term Born Infants NCT06421506 | King's College Hospital NHS Trust | N/A |
| Completed | Imputation of Arterial Oxygen Partial Pressures Using Pulse Oximetry NCT06283914 | American University of Beirut Medical Center | — |
| Unknown | Oxygenation Efficacy of "Intrinseque Health" Non-Rebreathing Mask ("IHNRM") NCT06310629 | China Medical University Hospital | N/A |
| Unknown | Sedative Effect and Safety of Remimazolam Besylate in ARDS Patients NCT05758597 | Zhiming Jiang | Phase 4 |
| Recruiting | Non Inferiority Trial Investigating Surfactants Administered Via MIST NCT06074380 | Endeavor Health | Phase 4 |
| Completed | Pain Assessment During Less-Invasive-Surfactant-Administration NCT06150586 | University of Zurich | — |
| Recruiting | The Role of Lung Ultrasonography Score in Predicting Prognosis in Term and Late Preterm Newborns With Postnata NCT06031324 | Bursa City Hospital | — |
| Withdrawn | Comparing Different Delivery Systems of Continuous Positive Airway Pressure in Neonates NCT06038565 | Massachusetts General Hospital | N/A |
| Completed | The Relationship of Fetal Lung Elastography Values With the Development of Respiratory Distress in Cases of Pr NCT06168149 | Ankara Etlik City Hospital | — |
| Completed | Definition and Management of Right Ventricular Injury in Adult Patients Receiving Extracorporeal Membrane Oxyg NCT05948332 | Prashant Nasa | — |
| Recruiting | Influence of Flow Rate Change on CO2 Levels During High Flow Nasal Ventilation (HFNV) in Preterm Infants. NCT06622902 | Rambam Health Care Campus | N/A |
| Recruiting | Effects of Flow Magnitude on Cardiorespiratory Stability During Nasal High Flow Therapy in Preterm Infants NCT05908227 | Insel Gruppe AG, University Hospital Bern | N/A |
| Completed | Implementing LISA Surfactant in Nigeria NCT05714865 | Indiana University | Phase 4 |
| Unknown | Effect of High Flow Nasal Cannula Versus Nasal Continuous Positive Airway Pressure NCT05849116 | Assiut University | — |
| Completed | Nasal Intermittent Positive Pressure Ventilation During Neonatal Intubation NCT06549283 | Muğla Sıtkı Koçman University | N/A |
| Recruiting | Spinal Cord Stimulation to Shorten Ventilator Dependence in ARDS Patients NCT05928052 | University of California, Los Angeles | N/A |
| Unknown | Predictive Value of PS Application in Premature Infants With RDS NCT05772247 | The First Hospital of Jilin University | — |
| Completed | Ventilatory Variables in Subjects With Acute Respiratory Distress Syndrome Due to COVID-19 NCT05946525 | Hospital Donación Francisco Santojanni | — |
| Active Not Recruiting | Non-invasive Ventilation in Preterm Infants NCT05987800 | Universitair Ziekenhuis Brussel | N/A |
| Unknown | Comparison of INRECSURE and LISA in Preterm Neonates With RDS NCT05711966 | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | N/A |
| Unknown | Changes in Lung Aeration and Inspiratory Effort With and Without Awake Prone NCT05719103 | Shanghai Zhongshan Hospital | N/A |
| Unknown | Prone Positioning vs. Prone Positioning and NO Inhalation in COVID-19 ARDS. NCT05715788 | Shanghai Zhongshan Hospital | — |
| Completed | Facilitated Tucking Position During Endotracheal Suctioning NCT06428916 | Kafrelsheikh University | N/A |
| Completed | Recruitment Manoeuvres in Critically Ill Patients NCT05508724 | University of Oxford | — |
| Withdrawn | Confirmation of Tube Placement in Newborns NCT05229887 | University of Alberta | N/A |
| Completed | Comparison of Two Respiratory Physiotherapy Treatments in Postcovid-19 Patients. NCT05435443 | Universidad Católica de Ávila | N/A |
| Completed | The Association Between Respiratory Effort Parameters During the First 48 Hours With Clinical Outcomes in Mech NCT06433076 | Ramathibodi Hospital | — |
| Completed | Comparison of the Acute Effects of Chest Physiotherapy Methods Applied in Different Positions in Preterm Newbo NCT05036603 | Sanko University | N/A |
| Completed | A Low-Resource Oxygen Blender Prototype for Use in Modified Bubble CPAP Circuits NCT04311320 | University of Minnesota | N/A |
| Completed | Functional Residual Capacity During Different Levels of High-flow in Preterm Infants NCT05237622 | University of Zurich | N/A |
| Completed | LISA vs INSURE in Extremely Low Birth Weight Infants. A Manikin Study NCT04944108 | University Hospital Padova | N/A |
| Unknown | Vitamin D Supplementation and Clinical Outcomes in Severe COVID-19 Patients NCT05384574 | University Hospital of Split | N/A |
| Completed | Feasibility of Use of the PATH bCPAP and Oxygen Blenders Device With Neonates in Uganda NCT05462509 | PATH | N/A |
| Completed | The Effect of Music Therapy in COVID-19 Patients Given Prone Position NCT05038514 | Kutahya Health Sciences University | N/A |
| Completed | CPAP Or Nasal Cannula Oxygen for Preterm Infants: A Randomized Controlled Trial NCT04792099 | University of Alabama at Birmingham | N/A |
| Completed | LISA in the Delivery Room for Extremely Preterm Infants NCT04715373 | University of Texas Southwestern Medical Center | N/A |
| Completed | Efficacy of FES Cycling After a Severe Form of COVID-19 NCT04841746 | Hospices Civils de Lyon | N/A |
| Unknown | Medium vs Low Oxygen Threshold for the Surfactant Administration NCT04199364 | Virgilio Paolo Carnielli | Phase 4 |
| Unknown | Efficacy and Safety of Selective Digestive Decontamination in the ICU With High Rates of Antibiotic-resistant NCT04839653 | MEDSI Clinical Hospital 1, ICU | N/A |
| Unknown | Exogenous Surfactant Through Nebulizer Mask on Clinical Outcomes in Covid-19 Patients NCT04847375 | Shahid Beheshti University of Medical Sciences | N/A |
| Active Not Recruiting | The Budesonide in Babies (BiB) Trial NCT04545866 | NICHD Neonatal Research Network | Phase 3 |
| Completed | Surfactant Nebulization for the Early Aeration of the Preterm Lung NCT04315636 | University of Zurich | Phase 3 |
| Terminated | Diaphragm Dysfunction in ARDS Patients With V-V ECMO NCT04613752 | Assistance Publique - Hôpitaux de Paris | N/A |
| Unknown | Fenofibrate for Patients With COVID-19 Requiring Hospitalization NCT04661930 | Yaakov Nahmias | Phase 3 |
| Recruiting | Surfactant for Neonatal Respiratory Distress Syndrome(NRDS) and Neonatal Acute Respiratory Distress Syndrome(N NCT04777760 | Daping Hospital and the Research Institute of Surgery of the Third Military Medical University | — |
| Unknown | Comparison of the Results of Transcutaneous Carbon Dioxide and Oxygen Pressure in Premature Neonates Who Under NCT04505176 | Hacettepe University | — |
| Unknown | The ECOVITA Study - Validation of LUS Score in SARS-CoV-2 Disease, i.e COVID-19 NCT04871685 | University of Campania Luigi Vanvitelli | — |
| Completed | Comparison of Efficacy of Less Invasive Surfactant Treatment Under Nasal CPAP and Nasal IPPV NCT04698473 | Uludag University | N/A |
| Completed | Impact of Prone Position in Patients Under Spontaneous Breathing on Intubation or Non-invasive Ventilation or NCT04363463 | Centre Hospitalier Régional d'Orléans | N/A |
| Withdrawn | LIBERATE Trial in COVID-19 NCT04334629 | King's College London | Phase 4 |
| Completed | COVid-19: Awake Proning and High-flow Nasal Cannula in respiratorY DistrEss NCT04395144 | Hôpital de Verdun | N/A |
| Unknown | Mechanical Ventilation Strategy for Coronavirus Disease 2019 (COVID-19) NCT04497454 | University of Sao Paulo General Hospital | N/A |
| Suspended | BAttLe Against COVID-19 Using MesenchYmal Stromal Cells NCT04348461 | Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz | Phase 2 |
| Completed | Pathological Findings of Fatal COVID-19 NCT04675281 | Nantes University Hospital | — |
| Completed | Place of ECMO in the Management of Severe Refractory ARDS Associated With Covid-19 NCT04343404 | University Hospital, Strasbourg, France | — |
| Unknown | Assessment of the Effectiveness of Vibroacoustic Therapy for Respiratory Failure Caused by COVID 19 NCT04435353 | Astana Medical University | N/A |
| Recruiting | Forced Oscillometry in Infants With Bronchopulmonary Dysplasia NCT04270045 | Winston Manimtim | — |
| Completed | Early Caffeine and LISA Compared to Caffeine and CPAP in Preterm Infants NCT04209946 | Sharp HealthCare | N/A |
| Completed | Extending CPAP Therapy in Stable Preterm Infants to Increase Lung Growth and Function NCT04295564 | Cynthia McEvoy | N/A |
| Unknown | Telemedicine in the Generals Practitioners Office NCT04168554 | Rijnstate Hospital | — |
| Unknown | Surfactant Administration Via Thin Catheter Using a Specially Adapted Video Laryngoscope NCT03846960 | HaEmek Medical Center, Israel | N/A |
| Unknown | Use of Gentle Synchronized Negative Pressure in Helping Babies Breathe NCT03510169 | Unity Health Toronto | N/A |
| Unknown | Postoperative Respiratory Abnormalities NCT04079829 | Efficacy Care R&D Ltd | — |
| Completed | Caffeine Treatment in in the Delivery Room NCT04044976 | University of Florence | N/A |
| Completed | Intratracheal Budesonide/Surfactant Prevents BPD NCT03275415 | Taipei Medical University | Phase 4 |
| Terminated | Open Lung Strategy, Gas Distribution and Right Heart Function in ARDS Patients NCT03202641 | Massachusetts General Hospital | N/A |
| Withdrawn | Study on the Effects of Different Premedication for LISA on Stress and Cerebral Tissue Oxygenation in Preterm NCT03718507 | ASST Fatebenefratelli Sacco | Phase 1 |
| Completed | Lung Ultrasound to Guide Surfactant Therapy NCT04330443 | Institut Investigacio Sanitaria Pere Virgili | N/A |
| Unknown | Ventilator Induced Diaphragm Dysfunction in Pediatric Critically Ill Patients (VIDD) NCT03768232 | Bambino Gesù Hospital and Research Institute | — |
| Completed | Low Frequency, Ultra-low Tidal Volume Ventilation in Patients With ARDS and ECMO NCT03764319 | Medical University of Vienna | N/A |
| Completed | The Hilo Pilot -Trial to Assess Feasibility NCT03706586 | University of Alberta | N/A |
| Completed | The Effect of Surfactant Dose on Outcomes in Preterm Infants With RDS NCT03808402 | Chiesi UK | — |
| Completed | PECO Air Purification in Hospital Rooms to Improve Health Outcomes for Pediatric Respiratory Distress NCT03647397 | Molekule | N/A |
| Completed | Identifying PARDS Endotypes NCT03539783 | Children's Hospital Medical Center, Cincinnati | — |
| Unknown | Optimal Settings of Non Invasive Respiratory Support in Preterm Newborns NCT03592134 | Hôpital Necker-Enfants Malades | — |
| Completed | Ventilatory Monitoring in Children With Respiratory Distress Syndrome With Electrical Impedance Tomography NCT03768921 | Universidade Metodista de Piracicaba | N/A |
| Completed | Effects of Kinesiotaping on Respiratory Muscles in Very Preterm Infants NCT06285669 | Ondokuz Mayıs University | N/A |
| Unknown | Efficacy of Adding Budesonide to Poractant Alfa to Prevent Bronchopulmonary Dysplasia. NCT03521063 | Hospital Central "Dr. Ignacio Morones Prieto" | Phase 4 |
| Completed | Benefit of Clarithromycin in Patients With Severe Infections Through Modulation of the Immune System NCT03345992 | Hellenic Institute for the Study of Sepsis | Phase 3 |
| Terminated | CPAP vs.Unsynchronized NIPPV at Equal Mean Airway Pressure NCT03670732 | Women and Infants Hospital of Rhode Island | N/A |
| Completed | A Comparison of Methods of Discontinuing Nasal CPAP in Premature Infants <30 Weeks Gestation NCT03292562 | The University of Texas Health Science Center, Houston | N/A |
| Unknown | Bi-level Positive Airway Pressure for Respiratory Distress Syndrome in Twins Infants NCT03235661 | Daping Hospital and the Research Institute of Surgery of the Third Military Medical University | N/A |
| Completed | Mid and Standard Frequency Ventilation in Infants With Respiratory Distress Syndrome NCT03231735 | University of Alabama at Birmingham | Phase 2 / Phase 3 |
| Completed | n-CPAP Versus n-BiPAP and NIPPV for Postextubation in RDS in Preterms NCT01770925 | Ain Shams University | N/A |
| Completed | Nasal High Frequency Oscillation Ventilation(NHFOV) for Respiratory Distress Syndrome NCT03140891 | Daping Hospital and the Research Institute of Surgery of the Third Military Medical University | N/A |
| Completed | Comparison of Aerosol Delivery of Infasurf to Usual Care in Spontaneously Breathing RDS Patients NCT03058666 | ONY | Phase 3 |
| Suspended | Paracetamol vs Ibuprofen for PDA Closure in Preterm Infants. NCT02056223 | University of Padova | Phase 2 / Phase 3 |
| Completed | Earliest Lung Ultrasound Time for Predicting the Need of Surfactant NCT04544514 | Gozdem Kayki | — |
| Completed | Effects of Non-invasive Ventilation With Helium-oxygen Mixture in Premature Infants With Respiratory Distress NCT04404816 | Poznan University of Medical Sciences | Phase 1 / Phase 2 |
| Unknown | Diaphragm Electrical Activity of Preterm Infants on nCPAP With Binasal Prongs Versus RAM Cannula NCT03121781 | Sunnybrook Health Sciences Centre | N/A |
| Unknown | NIPPV and nBiPAP Methods in Preterm Infants With Respiratory Distress Syndrome NCT02901652 | Zekai Tahir Burak Women's Health Research and Education Hospital | N/A |
| Unknown | SLI MANEUVER and RESPIRATORY MORBIDITIES NCT02887924 | Zekai Tahir Burak Women's Health Research and Education Hospital | Phase 4 |
| Completed | Video Laryngoscopy in Newborn Babies V1 NCT03265548 | Royal Devon and Exeter NHS Foundation Trust | N/A |
| Unknown | Efficacy and Safety of Goat Lung Surfactant for the Treatment of Respiratory Distress Syndrome in Preterm Neon NCT02774044 | Ramesh K Agarwal | Phase 2 / Phase 3 |
| Withdrawn | Sustained Lung Inflation and Pulmonary Mechanics in Preterm Infant NCT02493920 | Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico | N/A |
| Completed | Implementation of Lung Protective Ventilation in Patients With Acute Respiratory Failure NCT03225807 | Intermountain Health Care, Inc. | — |
| Completed | nHFOV vs nCPAP: Effects on Gas Exchange for the Treatment of Neonates Recovering From RDS NCT02772835 | Fondazione Poliambulanza Istituto Ospedaliero | N/A |
| Unknown | Does The Surfactant Administration by Aerosolization Effective? NCT02825953 | nihat demir | N/A |
| Completed | Performance Evaluation of Clinical Ultrasound in Management of Acute Pulmonary Edema in Elderly Patient NCT02638350 | University Hospital, Toulouse | N/A |
| Completed | The Safety and Efficacy of Lucinactant for Inhalation in Premature Neonates 26 to 32 Weeks Gestational Age NCT02636868 | Windtree Therapeutics | Phase 2 |
| Completed | Fetal Lung Volume and Pulmonary Artery Resistance Index Measurement in Term Diabetic Pregnancy NCT02586922 | Ain Shams University | — |
| Completed | Efficacy of a New Technique -"IN-REC-SUR-E"- in Preterm Neonates With RDS NCT02482766 | Catholic University of the Sacred Heart | N/A |
| Terminated | Trial To Assess The Safety And Tolerability Of Lucinactant For Inhalation In Preterm Neonates 26 to 28 Weeks P NCT02528318 | Windtree Therapeutics | Phase 2 |
| Completed | The Predictive Value of Amniotic Fluid pH and Electrolytes on Neonatal Respiratory Disorders NCT02813954 | Kanuni Sultan Suleyman Training and Research Hospital | — |
| Completed | The Possible Effect Of Amniotic Fluid pH On Neonatal Morbidities In Maternal Inflammation/Infection Associated NCT02691559 | Kanuni Sultan Suleyman Training and Research Hospital | N/A |
| Terminated | (S5-SAMU) Randomized Study Comparing the ASV (Adaptative Support Ventilation) to Conventional Ventilation NCT02348047 | Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer | Phase 4 |
| Completed | Curosurf/Budesonide for Infants With Respiratory Distress Syndrome NCT02013115 | Daping Hospital and the Research Institute of Surgery of the Third Military Medical University | N/A |
| Completed | Comparative Effectiveness Study of Bubble CPAP Devices in the NICU NCT02392806 | Marya Strand, MD | N/A |
| Withdrawn | Oscillatory Versus Non-Oscillatory Nasal Continuous Airway Pressure Neonatal Respiratory Support NCT01277874 | University of Utah | N/A |
| Completed | Duration of Continuous Positive Airway Pressure and Pulmonary Function Testing in Preterm Infants NCT02249143 | Oregon Health and Science University | N/A |
| Completed | Electrical Activity of Diaphragm as a Means to Predict Extubation Success in Preterm Infants NCT02144363 | Dartmouth-Hitchcock Medical Center | — |
| Completed | Trial to Assess the Safety and Tolerability of Lucinactant for Inhalation in Premature Neonates NCT02074059 | Windtree Therapeutics | Phase 2 |
| Unknown | Impact of Synchronized Nasal Intermittent Positive Pressure Ventilation Using NAVA in Preterm Infants With RDS NCT02030652 | Hospital Israelita Albert Einstein | N/A |
| Completed | Comparing Weaning of Nasal Continuous Positive Airway Pressure (CPAP) From Preterm Infants NCT02126501 | Maimonides Medical Center | N/A |
| Completed | Comparing Bubble and Ventilator Nasal CPAP in Preterm Infants NCT02003846 | Maimonides Medical Center | — |
| Suspended | NHFOV Versus NCPAP to Prevent Exubation Failure NCT01852916 | University of Manitoba | N/A |
| Completed | Impact of Different Modes of Noninvasive Ventilation on Regional Oximetry and Hemodynamics in Premature Newbor NCT01942967 | University of Manitoba | — |
| Completed | Comparison of Curosurf and Infasurf in the Treatment of Preterm Infants With Respiratory Distress Syndrome NCT02834624 | University of Missouri-Columbia | N/A |
| Unknown | ECALMIST Versus InSurE in Preterm Infant < 32 Weeks,Multicenter, Multinational RCT NCT01848262 | University of Manitoba | N/A |
| Completed | Proper Pressure and Duration of Sustained Lung Inflation in Preterm Infants NCT02846597 | Mansoura University Children Hospital | Phase 1 |
| Completed | A Multi-center Trial to Determine if Curosurf® Reduces the Duration of Mechanical Ventilation in Very Preterm NCT01709409 | Ottawa Hospital Research Institute | Phase 3 |
| Unknown | Use of the Medical Device DECAP CO2 for the Treatment of Hypercapnic Respiratory Distress in Patients Under No NCT01774422 | University Hospital, Clermont-Ferrand | Phase 2 |
| Completed | Observational Study Evaluating the Use of Intellivent® for Patients With Respiratory Distress Syndrome NCT01489085 | Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer | — |
| Completed | Heliox in Preterm Infants With Respiratory Distress Syndrome NCT01759316 | Third Military Medical University | N/A |
| Completed | Improved Accessibility of EmONC Services for Maternal and Newborn Health: a Community Based Project NCT01751945 | Aga Khan University | N/A |
| Completed | Cord Blood 25(oh)-Vitamin D Level in Preterm Infants and Associated Morbidities NCT01812681 | Dr. Sami Ulus Children's Hospital | — |
| Completed | Evaluation of the Diagnostic Performance of Electrical Impedance Tomography to Detect Situations at Risk of Le NCT02896673 | Hospices Civils de Lyon | N/A |
| Completed | Comparison Between Infant Flow SiPAP and Noninvasive NAVA in the Neonatal Intensive Care Unit NCT01588080 | Fraser Health | N/A |
| Unknown | Is Synchronization More Effective During Noninvasive Ventilation in Immediately Extubated Preterm Infants? NCT01664832 | Prof. Dr. Helmut Hummler | N/A |
| Withdrawn | Comparison in Pulmonary Compliance Between Curosurf and Survanta in Preterm Infants With Respiratory Distress NCT01537354 | University of Michigan | N/A |
| Completed | Early CPAP And Large Volume Minimally Invasive Surfactant (ECALMIST) in Preterm Infants With RDS NCT01553292 | University of Manitoba | N/A |
| Completed | Effects of Bolus Surfactant Therapy on Peripheral Perfusion Index and Tissue Carbon Monoxide NCT01923844 | Ege University | Phase 4 |
| Unknown | Minimally Invasive Surfactant Therapy Followed by CPAP (MISTCPAP) in Preterm Infants With RDS NCT01723683 | China Medical University Hospital | Phase 2 |
| Unknown | Intranasal Midazolam Versus Intranasal Ketamine to Sedate Newborns for Intubation in Delivery Room NCT01517828 | University Hospital, Montpellier | Phase 3 |
| Unknown | Sustained Lung Inflation in the Delivery Room in Preterm Infants at High Risk of Respiratory Distress Syndrome NCT01440868 | University of Florence | N/A |
| Completed | Lung Ultrasound to Diagnose Transient Tachypnea of the Newborn (TTN) Versus Respiratory Distress Syndrome (RDS NCT01517958 | Icahn School of Medicine at Mount Sinai | — |
| Terminated | Extubation Readiness Study in Very Low Birthweight Infants NCT01471431 | University of Pennsylvania | N/A |
| Withdrawn | Autologous Umbilical Cord Blood Transfusion for Preterm Neonates NCT01121328 | Sahar M.A. Hassanein, MD | Phase 1 |
| Withdrawn | Pre Hospital Evaluation of Video Laryngoscopy NCT01374061 | Assistance Publique - Hôpitaux de Paris | Phase 4 |
| Completed | Laryngeal Mask Airway (LMA) for Surfactant Administration in Neonates NCT01116921 | University of Minnesota | N/A |
| Completed | Premedication for Non-Emergency Endotracheal Intubation In the NICU NCT01749501 | Martin Espinosa, MD | Phase 4 |
| Suspended | The Effect of Surfactant Administration on Cerebral Oxygenation NCT01258517 | Zekai Tahir Burak Women's Health Research and Education Hospital | — |
| Completed | Antenatal Late Preterm Steroids (ALPS): A Randomized Placebo-Controlled Trial NCT01222247 | The George Washington University Biostatistics Center | Phase 3 |
| Completed | Characterization of the Cord Blood Stem Cell in Situation of Neonatal Asphyxia NCT01284673 | Assistance Publique Hopitaux De Marseille | N/A |
| Completed | Observational Crossover Study Comparing Oxygenation and Ventilation Using SiPAP Versus CPAP in LBW Infants NCT01053455 | Children's Hospitals and Clinics of Minnesota | — |
| Unknown | High Flow Nasal Cannula (HFNC) Versus Nasal Intermittent Mandatory Ventilation (NIMV)for Respiratory Distress NCT01189162 | Bnai Zion Medical Center | N/A |
| Terminated | Clinical Evaluation of a Closed Loop Oxygen Controller for Neonatal Respiratory Care NCT00887731 | University of Utah | — |
| Completed | High Flow Nasal Cannula in Comparison With Nasal Continuous Positive Airway Pressure in the Management of Resp NCT02587832 | Sidra Medicine | N/A |
| Unknown | Prevention of Chronic Lung Disease (CLD) in Preterm Infants NCT00883532 | China Medical University, China | Phase 4 |
| Completed | Weaning Preterm Neonates From Nasal Continuous Positive Airway Pressure NCT01093495 | Mansoura University | N/A |
| Unknown | Propofol Versus Midazolam as Premedication for Preterm Neonates With Respiratory Distress Syndrome (RDS) NCT00797160 | Federal University of Minas Gerais | Phase 4 |
| Completed | Effect of Different Ventilatory Strategies on Cardiac Function in Patients With Acute Respiratory Failure NCT00713713 | Fondazione Poliambulanza Istituto Ospedaliero | N/A |
| Completed | Verification of Pulse Oximetry in Neonatal Population NCT00751439 | Children's Hospitals and Clinics of Minnesota | — |
| Completed | Study of a Novel Technique of Mechanical Ventilation in Patients With Severe Acute Respiratory Failure NCT00637507 | University of Athens | Phase 2 / Phase 3 |
| Completed | NCPAP + Heliox as a Treatment for Infant Respiratory Distress Syndrome (RDS) NCT01383850 | Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico | Phase 2 |
| Completed | Nasal Intermittent Positive Pressure Ventilation In Newborn Infants With Respiratory Distress Syndrome NCT00780624 | Third Military Medical University | N/A |
| Withdrawn | Comparison of Two Fetal Lung Maturity Tests NCT00613977 | Oklahoma State University Center for Health Sciences | — |
| Completed | Trial of Non Invasive Ventilation for Respiratoy Distress Syndrome NCT00821119 | Instituto Materno Infantil Prof. Fernando Figueira | N/A |
| Completed | High-frequency Oscillatory Ventilation (HFOV) in Preterm Infants With Severe Respiratory Distress Syndrome (RD NCT01496508 | Zhengzhou Children's Hospital, China | Phase 2 |
| Unknown | Early CPAP in Respiratory Distress Syndrome NCT00368680 | Pontificia Universidad Catolica de Chile | Phase 4 |
| Completed | Early NCPAP Before Surfactant Treatment in Very Preterm Infants With RDS NCT01996670 | Xiangya Hospital of Central South University | — |
| Completed | Humidified High Flow Nasal Cannula as Compared to Nasal Continuous Positive Airway Pressure NCT00356668 | Children's Hospitals and Clinics of Minnesota | Phase 3 |
| Withdrawn | Treatment of Elevated Arterial Pulmonary Pressure With Inhaled Iloprost NCT00216931 | Lund University Hospital | N/A |
| Suspended | Effects of Volume Guarantee With Pressure Supported vs. Synchronized Intermittent Mandatory Ventilation in VLB NCT00295230 | Children's Hospitals and Clinics of Minnesota | — |
| Unknown | Two Strategies of RDS Treatment in Newborns With Birth Weight > 1500 Grams NCT00277030 | Pontificia Universidad Catolica de Chile | Phase 4 |
| Completed | A Multicenter, Randomized, Open Label Trial of a New Animal Extracted Surfactant to Treat RDS in Preterm Infan NCT02305160 | University of Sao Paulo | Phase 2 / Phase 3 |
| Terminated | Curosurf and Survanta Treatment(CAST)of RDS in Very Premature Infants NCT00767039 | Alan Fujii | Phase 4 |
| Terminated | Feasibility Study of Aerosolized Surfaxin in the Prevention of Respiratory Distress Syndrome (RDS) in Prematur NCT00807235 | Windtree Therapeutics | Phase 2 |
| Completed | Pilot Trial of Surfactant Booster Prophylaxis For Ventilated Preterm Neonates NCT00208039 | Children's Hospital of Philadelphia | N/A |
| Terminated | Cytokine Change in Bronchoalveolar Lavage Fluid After Early Budesonide-Surfactant Treatment in Premature Infan NCT00146497 | China Medical University Hospital | Phase 4 |
| Completed | Remifentanil Versus Morphine for Sedation of Premature Neonates With Respiratory Distress Syndrome NCT00391105 | Federal University of Minas Gerais | Phase 4 |
| Completed | Very Early Surfactant and NCPAP for Premature Infants With RDS NCT00563641 | Colombian Neonatal Research Network | Phase 3 |
| Completed | Pilot Trial of Surfactant Therapy For Preterm Neonates 5-21 Days Old With Respiratory Decompensation NCT00165074 | Children's Hospital of Philadelphia | N/A |
| Completed | Antenatal Betamethasone Compared to Dexamethasone - "BETACODE TRIAL" NCT00418353 | University of Oklahoma | N/A |
| Terminated | Antenatal Rescue Course of Glucocorticoids in Threatened Premature Birth NCT00295464 | University of Oulu | Phase 4 |
| Terminated | Early Surfactant to Reduce Use of Mechanical Breathing in Low Birth Weight Infants NCT00005774 | NICHD Neonatal Research Network | Phase 3 |
| Completed | Carperitide in Acute Respiratory Distress Syndrome (ARDS) NCT00030121 | Suntory Pharmaceutical | Phase 2 |
| Completed | Phase I Study of Vasoactive Intestinal Peptide in Patients With Acute Respiratory Distress Syndrome and Sepsis NCT00004494 | Stony Brook University | Phase 1 |
| Completed | Study of Antenatal Thyrotropin-Releasing Hormone in Women in Premature Labor to Prevent Lung Disease in Preter NCT00004840 | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | N/A |
| Terminated | Minimal Breathing Support and Early Steroids to Prevent Chronic Lung Disease in Extremely Premature Infants (S NCT00005777 | NICHD Neonatal Research Network | Phase 3 |
| Unknown | Study of Energy Requirements in Critically Ill Newborns NCT00006274 | National Center for Research Resources (NCRR) | — |
| Completed | Study of the Pathobiology of Bronchopulmonary Dysplasia in Newborns NCT00006058 | National Center for Research Resources (NCRR) | — |
| Completed | Impact of Surfactant's Availability on Newborns NCT00005432 | National Heart, Lung, and Blood Institute (NHLBI) | — |
| Completed | Phase III Randomized, Double-Blind, Placebo-Controlled Study of Antenatal Thyrotropin-Releasing Hormone in Pre NCT00004778 | National Center for Research Resources (NCRR) | Phase 3 |
| Completed | Study of the Effect of Four Methods of Cardiopulmonary Resuscitation Instruction on Psychosocial Response of P NCT00004805 | National Center for Research Resources (NCRR) | N/A |
| Completed | Risk Factors in Bronchopulmonary Dysplasia (Newborn Lung Project) NCT00005289 | University of Wisconsin, Madison | — |
| Completed | Clinical Interventions in Respiratory Distress Syndrome and Neonatal Lung Injury - SCOR in Lung Biology and Di NCT00005683 | University of Rochester | — |
| Completed | Human Surfactant Treatment of Respiratory Distress Syndrome Bicenter Trial NCT00000570 | National Heart, Lung, and Blood Institute (NHLBI) | Phase 3 |
| Completed | High Frequency Ventilation in Premature Infants (HIFI) NCT00000567 | National Heart, Lung, and Blood Institute (NHLBI) | Phase 3 |
| Completed | Prevention of Neonatal Respiratory Distress Syndrome With Antenatal Steroid Administration NCT00000563 | National Heart, Lung, and Blood Institute (NHLBI) | Phase 3 |