NCT01277874

Oscillatory Versus Non-Oscillatory Nasal Continuous Airway Pressure Neonatal Respiratory Support

• Status: Withdrawn
• Phase: N/A
• Study type: Interventional
• Enrollment: 0 (actual)
• Sponsor: University of Utah · Academic / Other
• Sex: All
• Age: 28 Days
• Healthy volunteers: Not accepted

Summary

This study will seek to enroll neonates requiring Nasal Continuous Airway Pressure (NCPAP) respiratory support and randomize them to either oscillatory (Osc-NCPAP, study group) or non-oscillatory (NCPAP, control group) mode. The goal of the research is to determine if Osc-NCPAP provides improved ventilation support compared to routine NCPAP, i.e. NCPAP without oscillations. This will be measured by need for change to ventilator support, improvement in pCO2 values, and reduction in respiratory rate and frequency of apnea during the period of NCPAP treatment. Other respiratory outcomes will also be compared, including time on NCPAP, time on High-Flow Nasal Cannula support following NCPAP, and time-averaged PiO2 from start of study to end of respiratory treatment.

Conditions

• Respiratory Distress Syndrome
• Prematurity

Interventions

Type	Name	Description
DEVICE	Nasal CPAP	NCPAP is delivered via nasal prongs placed into infant's nares. It may be delivered via ventilator or by bubble.
DEVICE	Oscillatory NCPAP	Bird Industries pneumatic diaphragm is attached to NCPAP patient circuit to provide oscillations.

Timeline

• Start date: 2014-12-01
• Primary completion: 2017-04-01
• Completion: 2017-04-01
• First posted: 2011-01-17
• Last updated: 2017-03-13

Locations

3 sites across 1 country: United States