NCT03235661

Bi-level Positive Airway Pressure for Respiratory Distress Syndrome in Twins Infants

Bi-level Positive Airway Pressure for Respiratory Distress Syndrome in Twins:A Randomized Controlled Trials

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 300 (estimated)
• Sponsor: Daping Hospital and the Research Institute of Surgery of the Third Military Medical University · Academic / Other
• Sex: All
• Age: 5 Minutes – 6 Hours
• Healthy volunteers: Not accepted

Summary

The investigators compared advantages and disadvantages of two forms of noninvasive respiratory support -bi-level positive airway pressure(BiPAP) or nasal continuous positive airway pressure (nCPAP) -as a primary mode of ventilation in preterm twins infants with respiratory distress syndrome

Detailed description

Invasive ventilation is related to development of adverse pulmonary and nonpulmonary outcomes in ventilated infants. Various modes of noninvasive respiratory support are being increasingly used to minimize the incidence of bronchopulmonary dysplasia (BPD). The aim of this trial to compare the effects of bi-level positive airway pressure(BiPAP) and nasal continuous positive airway pressure (NCPAP) in preterm twins infants as the primary mode.

Conditions

• nCPAP
• BiPAP
• Respiratory Distress Syndrome

Interventions

Type	Name	Description
DEVICE	BiPAP	BiPAP is used as a primary mode of ventilation in one of the preterm infants with respiratory distress syndrome
DEVICE	nCPAP	nCPAP is used as a primary mode of ventilation in another of the preterm infants with respiratory distress syndrome

Timeline

• Start date: 2017-08-15
• Primary completion: 2022-12-15
• Completion: 2022-12-15
• First posted: 2017-08-01
• Last updated: 2021-02-16

Locations

1 site across 1 country: China