NCT03546543

The Effects of Position on the Oxygenation Instability of Premature Infants as Documented by SpO2 Histograms

The Effects of Prone Versus Supine Position on the Oxygenation Instability of Premature Infants as Documented by SpO2 Histograms

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 23 (actual)
• Sponsor: Rambam Health Care Campus · Academic / Other
• Sex: All
• Age: 14 Days
• Healthy volunteers: Not accepted

Summary

SpO2 instability is in the nature of premature infants. Hypoxic episodes occur spontaneously in many of these infants, especially after the first week of life. Different interventions have been shown to influence the incidence of hypoxemic episodes in premature infants. A few studies point towards potential clinical benefits of better oxygenation and less hypoxic events by positioning very low birth weight infants prone, though a recent meta-analysis didn't find a clear benefit of prone position. The aim of this study is to evaluate the changes in oxygenation among preterm infants receiving respiratory support when positioned prone versus supine, as documented by SpO2 histograms.

Conditions

• Premature Infant
• Bronchopulmonary Dysplasia

Interventions

Type	Name	Description
PROCEDURE	Position change	Each subject will serve as his or her own control. Half of the infants will be placed supine for 3 hours, followed by 3 hours of prone positioning and back to supine for 3 hours and the other half will be start in prone position with consecutive periods of supine and then prone

Timeline

• Start date: 2018-01-01
• Primary completion: 2019-12-31
• Completion: 2020-03-30
• First posted: 2018-06-06
• Last updated: 2020-04-02

Locations

1 site across 1 country: Israel