| Recruiting | Reducing Blood Loss During Myomectomy:Uterine Artery Ligation Vs Pericervical Tourniquet NCT07526311 | Cairo University | N/A |
| Recruiting | The Perioperative Outcome of Epinephrine Infusion and Tranexamic Acid in Knee Arthroplasty Surgery NCT07089251 | King Abdullah International Medical Research Center | Phase 4 |
| Recruiting | Tranexamic Acid for Second Trimester Dilation and Evacuation and Bleeding Outcomes NCT06820177 | University of California, San Diego | Phase 4 |
| Recruiting | Oxytocin Pharmacokinetics and Pharmacodynamics NCT05488457 | University of Chicago | Phase 2 |
| Completed | Impact of Different Instrument Modifications on Lateral Nasal Wall Osteotomy and Pterygomaxillary Separation i NCT06629935 | Bezmialem Vakif University | N/A |
| Not Yet Recruiting | D2 Versus D3 Dissection in Laparoscopic Right Hemicolectomy NCT06049758 | General Committee of Teaching Hospitals and Institutes, Egypt | N/A |
| Withdrawn | Tranexamic Acid (TXA) in Hip Arthroscopy NCT05710146 | Northwestern University | Phase 3 |
| Recruiting | Maternal-fetal Outcomes of Genital Blood Loss Beyond 18 Weeks of Pregnancy NCT06802874 | IRCCS Azienda Ospedaliero-Universitaria di Bologna | — |
| Completed | Evaluation of Physiological Variables and Detection of Blood Loss in Healthy Adults With Different Subject Pos NCT05980013 | Zynex Monitoring Solutions | N/A |
| Recruiting | Prospective Investigation of Intra-Articular Tranexamic Acid Use in Elective Hip Arthroplasty NCT06903299 | St. Anne's University Hospital Brno, Czech Republic | — |
| Active Not Recruiting | Pneumatic Tourniquet Versus no Tourniquet in Transfemoral Amputation NCT05550623 | University of Southern Denmark | N/A |
| Completed | Exploratory Assessment of the Quantra® System in Adult ECMO Patients NCT05426564 | HemoSonics LLC | — |
| Unknown | The Effect of Time Window for Umbilical Cord Clamping During Cesareans on Offspring Hemoglobin and Maternal Bl NCT05492214 | Peking University | N/A |
| Recruiting | Transfusion Surveillance in Anaesthesia NCT06403163 | Erasme University Hospital | — |
| Unknown | Cesarean Scar Pregnancy and Clinical Outcomes NCT05481606 | Peking University Third Hospital | — |
| Unknown | Blood Loss Measurement Using Electrical Impedance Tomography NCT05287334 | Czech Technical University in Prague | N/A |
| Unknown | Bipolar Sealer for Reduction of Blood Loss in Anterior Total Hip Arthroplasties NCT05356637 | North Texas Medical Research Institute, PLLC | N/A |
| Withdrawn | Tranexamic Acid for Blood Loss Minimization in Endoscopic Pituitary Surgery NCT04863339 | University of North Carolina, Chapel Hill | Phase 2 |
| Completed | Effect of Prophylactic Tranexamic Acid on Bleeding Outcomes for Dilation and Evacuation NCT04651166 | University of Hawaii | Phase 2 |
| Active Not Recruiting | LBNP Tolerance With Skin Warming After Exercise Cold Stress NCT06279897 | University of Colorado, Colorado Springs | N/A |
| Unknown | Clonidine Versus Tranexamic Acid in Reduction of Blood Loss NCT05371574 | Uwakwe Emmanuel Chijioke | Phase 1 |
| Withdrawn | Noninvasive Monitor of Vascular Volume Fluid Shifts NCT05080881 | Dartmouth-Hitchcock Medical Center | N/A |
| Unknown | Extended Postoperative Oral Tranexamic Acid in Knee Replacement NCT05099276 | Campbell Clinic | Phase 4 |
| Unknown | Tranexamic Acid During Excisional Burn Surgery NCT05507983 | Maasstad Hospital | Phase 3 |
| Completed | Validating a New Point-of-care Device for Estimation of Blood Count in Pregnant Women NCT05012202 | The University of Texas Medical Branch, Galveston | — |
| Unknown | Effect of Perioperative Tranexamic Acid on Blood Loss During Management of Maxillofacial Trauma NCT04494126 | College of Medical Sciences Teaching Hospital. Nepal | Phase 4 |
| Completed | Use of Tranexamic Acid in the Total Knee Arthroplasty. NCT05919615 | Damascus University | N/A |
| Unknown | Comparative Study Between the Efficacy of Verapamil and Bisoprolol on Reduction of Bleeding During Endoscopic NCT04356196 | Assiut University | EARLY_Phase 1 |
| Unknown | Compare Between the Effect of Topical Tranexamic Acid Versus Hydrogen Peroxide on Blood Loss in Spine Surgerie NCT05152186 | Minia University | Phase 3 |
| Completed | The Effect of Tranexamic Acid in Total Blood Loss During Proximal Femoral Nailing NCT05359172 | Haseki Training and Research Hospital | — |
| Recruiting | Local Tranexamic Acid During Vaginal Hysteractomy to Reduce Blood Loss NCT04760301 | Meir Medical Center | N/A |
| Completed | Clinical Evaluation of the CM-1500 in Postoperative Surgery Patients NCT04706221 | Zynex Monitoring Solutions | N/A |
| Completed | Blood Loss Assessment in the Limited Application of Tourniquet During Primary Unilateral TKA NCT05691751 | Damascus University | N/A |
| Unknown | Blood Loss and Preeclampsia NCT04777097 | University of Zurich | — |
| Unknown | Methods to Reduce Blood Loss in Abdominal Myomectomy NCT04595812 | Cairo University | Phase 4 |
| Completed | Clinical Investigation Evaluating a New Autotransfusion Device in Cardiac Surgery NCT04588350 | i-SEP | N/A |
| Completed | Autonomic Cardiovascular Control in Response to Blood Volume Reduction in Blood Donors NCT04499664 | Hvidovre University Hospital | — |
| Unknown | Treatment of Anemia With Intravenous Iron in Patients Listed for Orthotopic Liver Transplantation NCT04475887 | Medical University of Vienna | Phase 4 |
| Terminated | Estimating Blood Loss Using TritonTM in Vaginal Deliveries: A Validation Trial NCT04277962 | The University of Texas Medical Branch, Galveston | N/A |
| Completed | Oral Versus Intravenous Tranexamic Acid NCT04089865 | Hospital for Special Surgery, New York | Phase 4 |
| Withdrawn | Early Administration Of Tranexamic Acid And Acute Blood Loss In Patients With Hip Fractures NCT05518279 | Henry Ford Health System | Phase 3 |
| Completed | Hemostatic Agent Use and Intraoperative Blood Loss in Lumbar Spine Surgery NCT04058665 | Johns Hopkins University | — |
| Completed | Tranexamic Acid for Prevention of Hemorrhage in Cesarean Delivery NCT03856164 | University of Texas Southwestern Medical Center | Phase 2 / Phase 3 |
| Recruiting | Efficacy of Angiographic Embolization vs Non-embolization of Moderate/Poor Vascularized Vertebral Metastases o NCT03853434 | Istituto Ortopedico Rizzoli | N/A |
| Completed | Placental Cord Drainage After Vaginal Delivery NCT03487341 | Ain Shams University | N/A |
| Completed | Comparison and Analysis of Blood Loss Formulas NCT03516552 | Hospital Clinic of Barcelona | — |
| Unknown | the Effect of Misoprostol on Intra-operative Blood Loss During Myomectomy Operation NCT03483142 | ahmed nagy shaker ramadan | Phase 3 |
| Completed | Oral Tranexamic Acid vs. Oral Aminocaproic Acid to Reduce Blood Loss and Transfusion After Total Knee Replacem NCT03365999 | Universidad Autonoma de Nuevo Leon | Phase 2 |
| Terminated | Safety and Efficacy of Oral TXA in Reducing Blood Loss and Transfusion in Hip Fractures NCT02908516 | Yale University | Phase 4 |
| Unknown | Comparison of Robot Assisted Thoracic Surgery With Video Assisted Thoracic Surgery in Case of Lung Cancer NCT03152071 | Universitair Ziekenhuis Brussel | N/A |
| Completed | PMZ-2010 (Centhaquine) as a Resuscitative Agent for Hypovolemic Shock NCT04056065 | Pharmazz, Inc. | Phase 2 |
| Completed | The MAR Method Versus the Visual Estimation Method in Predicting External Blood Loss NCT06855472 | Betül Akbuğa Özel | N/A |
| Unknown | Effect of Low Tidal Volume on Blood Loss During Laparoscopic Hepatectomy NCT03399123 | Southwest Hospital, China | N/A |
| Completed | Internal Iliac Artery Ligation Before Cesarean Hysterectomy in Morbidly Adherent Placenta NCT03824873 | Ain Shams University | Phase 3 |
| Completed | Does the Use of Hemostatic Clips During the Tumor Resection Step Reduce Blood Loss During Robot-assisted Parti NCT04388917 | Centre Hospitalier Universitaire de Nice | — |
| Completed | Estimated Blood Loss: Novel Model for Estimating Surgical Blood Loss. NCT03249038 | Hospital Clinic of Barcelona | — |
| Completed | Terlipressin Infusion During Whipple Procedure: Effect on Blood Loss and Transfusion Needs NCT03572088 | Assiut University | Phase 2 |
| Unknown | An Algorithm for Predicting Blood Loss and Transfusion Risk in Fast Track Total Hip Arthroplasty NCT02750852 | Azienda Ospedaliera Bolognini di Seriate Bergamo | — |
| Completed | Tranexamic Acid Use and Blood Loss in Total Hip Arthroplasty NCT02989155 | Ohio State University | — |
| Withdrawn | The Effect of Tranexamic Acid on Transfusion Rates in Intertrochanteric Hip Fractures NCT01940536 | Hospital for Special Surgery, New York | Phase 4 |
| Completed | Investigation of Intravenous Tranexamic Acid With Anatomic and Reverse Total Shoulder Arthroplasty NCT02569658 | Rush University Medical Center | N/A |
| Terminated | Cooling the Uterus in C-section After Dysfunctional Labor NCT02910115 | Baylor Research Institute | N/A |
| Unknown | The Effects of Low-dose Epinephrine Plus Tranexamic Acid on Perioperative Haemostasis and Inflammatory Reactio NCT02864095 | Southwest Hospital, China | N/A |
| Unknown | Intravenous Versus Topical Administration of Low Dose Epinephrine Plus Combined Administration of Intravenous NCT02860221 | Southwest Hospital, China | N/A |
| Terminated | Evaluating the Use of Tranexamic Acid (TXA) in Total Joint Arthroplasty NCT03825939 | NYU Langone Health | Phase 4 |
| Completed | TXA vs. Amicar in Total Knee and Hip Arthroplasty NCT02030821 | Duke University | Phase 4 |
| Completed | Comparison of Topical and Intravenous Tranexamic Acid in Total Hip Arthroplasty NCT02312440 | Shanghai Jiao Tong University School of Medicine | Phase 3 |
| Completed | Effects of Oxytocin on Bleeding Outcomes During Dilation and Evacuation NCT02083809 | University of Hawaii | N/A |
| Unknown | Rectal Misoprostol and Blood Loss During Abdominal Hysterectomy NCT02265562 | Cairo University | Phase 3 |
| Unknown | Comparison of Active and Passive Perioperative Warming Techniques in Reducing Intraoperative Blood Loss NCT02214524 | Peking Union Medical College Hospital | N/A |
| Completed | Carbetocin Versus Syntometrine for Prevention of Postpartum Hemorrhage After Cesarean Section NCT02044549 | Cairo University | Phase 4 |
| Completed | Blood Loss Between Surgical Blade and Unipolar Electrocautery in TKA NCT02108327 | Thammasat University | N/A |
| Completed | The Efficacy and Safety of Using Tranexamic Acid by Different Means to Reduce Blood Loss During Total Knee Rep NCT02117128 | Xijing Hospital | Phase 4 |
| Completed | Evaluation of Intraarticular Tranexamic Acid to Reduction of Total Blood Loss Following Knee-Arthroplasty NCT02427412 | Hvidovre University Hospital | Phase 4 |
| Terminated | Butterfly Sensor With Rev K Version NCT01992003 | University of California, San Francisco | — |
| Completed | The Effects of Tourniquet Use in Total Knee Arthroplasty NCT02429713 | Peking University People's Hospital | N/A |
| Completed | Can Thrombelastography Predict Blood Loss in Patients With Hip Fractures NCT02297061 | Hvidovre University Hospital | — |
| Completed | Epidemiology of Severe Peroperative Bleeding During Scheduled Surgery NCT02311309 | University Hospital, Caen | — |
| Completed | The Effect on Blood Loss of Topical and Intravenous Tranexamic Acid in Cardiac Surgery Patients NCT01895101 | Amphia Hospital | Phase 4 |
| Unknown | Coblation in Endoscopic Sinus Surgery NCT01793987 | Western University, Canada | N/A |
| Terminated | Postoperative Bleeding Prevention in Massive Bone Tumour Resection NCT02153593 | Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau | Phase 3 |
| Completed | Prevention of Postoperative Bleeding in Subcapital Femoral Fractures NCT02150720 | Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau | Phase 3 |
| Completed | Evaluation of the Zynex Blood Volume Monitor in Healthy Adult Volunteers During a Blood Draw NCT01834612 | Zynex Monitoring Solutions | Phase 1 |
| Completed | Efficacy Comparison of Topical and Intravenous Tranexamic Acid to Reduce the Number of Blood Transfusions in T NCT01881568 | Hospital Universitario La Paz | Phase 3 |
| Completed | The Efficacy and Safety of Using Tranexamic Acid to Reduce Blood Loss In Simultaneous Bilateral Total Knee Art NCT02504125 | Xijing Hospital | Phase 4 |
| Withdrawn | Reduced Intra-operative Blood Loss in Pancreaticoduodenectomy for Pancreatic or Peri-ampullary Tumors; Monocen NCT01712971 | Baki Topal | — |
| Unknown | Comparison of Blood Loss Following Total Hip Arthroplasty With the Use of Three Thromboprophylactic Regimes: D NCT02085824 | Centre of Postgraduate Medical Education | N/A |
| Completed | Evaluation of the Zynex Blood Volume Monitor in Healthy Adult Patients During a Blood Draw NCT01846195 | Zynex Monitoring Solutions | N/A |
| Unknown | A Study of Anterior Approach Combined With Infrahepatic Inferior Vena Cava Clamping NCT01608386 | Eastern Hepatobiliary Surgery Hospital | N/A |
| Completed | Comparative Accuracy of Three Versions of Non-Invasive Hemoglobin Monitoring NCT01604668 | University of California, San Francisco | — |
| Unknown | Tranexamic Acid in Orthopaedic Trauma Surgery NCT02080494 | University of Tennessee | N/A |
| Completed | Tranexamic Acid for Unilateral Total Knee Arthroplasty NCT01594671 | Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau | Phase 3 |
| Completed | Clinical Evaluation of the Zynex Blood Volume Monitor (CM-1500) in Healthy Male Adult Subjects During a Blood NCT01646060 | Zynex Monitoring Solutions | Phase 1 |
| Terminated | Effect of Preoperative Buccal Misoprostol on Blood Loss in Second-trimester Dilation and Evacuation Abortion NCT01436266 | Boston University | Phase 3 |
| Terminated | Salient Aquamantys Spine Trial NCT01331499 | Salient Surgical Technologies | Phase 4 |
| Completed | Clinical Trial Comparing Tranexamic Acid (TXA) With Aquamantys Sealer in Total Knee Arthroplasty (TKA) NCT02374398 | Eastern Maine Medical Center | Phase 4 |
| Completed | Fibrin Sealant in Bilateral Simultaneous Total Knee Arthroplasty With Focus on Blood Loss, Pain, Swelling and NCT01472913 | Hvidovre University Hospital | Phase 4 |
| Completed | Role of Autologous Platelet Rich Plasma in Total Knee Arthroplasty NCT01563380 | Post Graduate Institute of Medical Education and Research, Chandigarh | N/A |
| Completed | Frozen Red Blood Cell Transfusions in Trauma Patients NCT01038557 | Oregon Health and Science University | N/A |
| Completed | Intraoperative Bleeding During Endoscopic Sinus Surgery NCT01014728 | University of Chicago | N/A |
| Completed | Sevoflurane as an Anesthetic During Dilation and Evacuation Procedures NCT01048658 | Oregon Health and Science University | Phase 4 |
| Completed | Modified Ultrafiltration in Cardiac Surgery NCT00998647 | Goethe University | — |
| Completed | Comparison of Three Methods of Hemoglobin Monitoring NCT00792597 | University of California, San Francisco | — |
| Completed | Blood Loss at the Time of First Trimester Surgical Abortion in Anticoagulated Women NCT00614432 | University of Hawaii | — |
| Completed | Effect of Intermittent Pedicle Clamping on Hepatocellular Injury During Liver Surgery NCT01099475 | Maastricht University Medical Center | N/A |
| Completed | The Use of FLOSEAL to Reduce Bleeding in Total Knee Replacement Surgery NCT00990288 | Hospital for Special Surgery, New York | Phase 4 |
| Completed | Tranexamic Acid in Pediatric Cardiac Surgery NCT00994994 | Okayama University | N/A |