NCT04760301

Local Tranexamic Acid During Vaginal Hysteractomy to Reduce Blood Loss

Local Tranexamic Acid During Vaginal Hysterectomy to Reduce Blood Loss

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 60 (estimated)
• Sponsor: Meir Medical Center · Academic / Other
• Sex: Female
• Age: 20 Years – 90 Years
• Healthy volunteers: Accepted

Summary

Assessing the efficiency of Prophylactic use of local tranexamic acid during vaginal hysterectomy to reduce blood loss during operation

Detailed description

This randomized control trial will investigate whether local tranexamic acid is efficient for decreasing bleeding during vaginal hysterectomy. The investigators will randomize local placebo (saline) vs. local 1 gr tranexamic acid; local 1gr tranexamic acid diluted in 10 ml saline and local 10 ml saline at the beginning of surgery.

Conditions

• Blood Loss

Interventions

Type	Name	Description
DRUG	local tranexamic acid injection	local tranexamic acid injection to cervix- 1 g tranexamic acid diluted in 10 ml saline
OTHER	local normal saline injection to cervix	local normal saline injection to the cervix- 20 ml saline

Timeline

• Start date: 2021-02-16
• Primary completion: 2025-07-01
• Completion: 2026-06-01
• First posted: 2021-02-18
• Last updated: 2025-05-06

Locations

2 sites across 1 country: Israel