NCT01038557

Frozen Red Blood Cell Transfusions in Trauma Patients

Efficacy and Safety of Frozen Red Blood Cells for Transfusion in Trauma Patients

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 254 (actual)
• Sponsor: Oregon Health and Science University · Academic / Other
• Sex: All
• Age: 15 Years – 100 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to look at red blood cell (RBC) transfusions in trauma patients and evaluate for any differences between the age of the RBCs and how they were stored. The investigators will specifically look for the following differences between study groups: 1. the transfused red blood cells' ability to delivery oxygen to the tissues 2. differences in biochemical markers in subjects and units transfused, and 3. how the subject's internal organs are working and if they develop any infections

Conditions

• Blood Loss
• Anemia
• Trauma

Interventions

Type	Name	Description
BIOLOGICAL	RBC units	When a transfusion is ordered, enrolled subjects will receive RBC units 1) up to 14 days old, 2) 14-42 days old, or 3) that are frozen when stored.

Timeline

• Start date: 2010-01-01
• Primary completion: 2014-05-01
• Completion: 2014-05-01
• First posted: 2009-12-24
• Last updated: 2020-01-28
• Results posted: 2020-01-28

Locations

5 sites across 1 country: United States