NCT02150720

Prevention of Postoperative Bleeding in Subcapital Femoral Fractures

Prevention of Postoperative Bleeding in Femoral Fractures: a Multicenter, Randomized, Controlled, Parallel Clinical Trial to Assess the Efficacy of Tranexamic Acid and Fibrin Glue

• Status: Completed
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 161 (actual)
• Sponsor: Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The main hypothesis of this clinical trial is that the use of intra-articular tranexamic acid and the fibrin glue plus usual hemostasis will reduce at least a 25% the postoperative blood loss with respect to usual hemostasis in patients undergoing subcapital femoral fractures.

Conditions

• Hip Fracture
• Blood Loss

Interventions

Type	Name	Description
DRUG	Tranexamic Acid	1g intra-articular before closing the wound surgery
DRUG	Fibrin glue	5mL intra-articular before closing the wound surgery
PROCEDURE	Electrocauterization	Coagulation blood from vessels by means of a electrocautery.

Timeline

• Start date: 2013-02-01
• Primary completion: 2015-04-01
• Completion: 2016-03-01
• First posted: 2014-05-30
• Last updated: 2016-09-20

Locations

6 sites across 1 country: Spain