NCT02083809

Effects of Oxytocin on Bleeding Outcomes During Dilation and Evacuation

A Randomized Double-blinded Controlled Trial Comparing Dilation and Evacuation Outcomes With and Without Oxytocin Use

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 166 (actual)
• Sponsor: University of Hawaii · Academic / Other
• Sex: Female
• Age: 14 Years – 50 Years
• Healthy volunteers: Not accepted

Summary

Currently, there is very little research to identify ways to decrease blood loss during D\&E (dilation and evacuation) procedures. The objective is to determine whether routine use of intravenous oxytocin will improve bleeding outcomes at the time of D\&E at 18-24-weeks gestation. To evaluate the hypothesis, investigators will perform a randomized, double-blinded, placebo-controlled trial. The patient will be followed until discharged from the postoperative care unit during which time patient satisfaction, pain score and postoperative bleeding will be assessed.

Conditions

• Abortion
• Dilation and Evacuation
• Hemorrhage
• Blood Loss

Interventions

Type	Name	Description
DRUG	intravenous oxytocin	30 units of oxytocin added to 500ml of inert IV fluid (saline, lactated ringer)
DRUG	Intravenous Fluids and Electrolytes	500 ml of inert IV fluid

Timeline

• Start date: 2014-10-01
• Primary completion: 2018-02-01
• Completion: 2018-02-01
• First posted: 2014-03-11
• Last updated: 2020-11-27
• Results posted: 2020-11-27

Locations

2 sites across 1 country: United States