Clinical Trials Directory

Trials / Sponsors / Shire

Shire

Industry · 351 registered clinical trials2 currently recruiting.

StatusTrialPhaseStarted
RecruitingA Study of Replagal in Children and Adults With Fabry Disease in India
Fabry Disease
Phase 42022-11-01
WithdrawnA Clinical Study of rhPTH(1-84) Treatment in Japanese Participants With Chronic Hypoparathyroidism
Chronic Hypoparathyroidism
Phase 32022-08-31
TerminatedA Study of Replagal in Treatment-naïve Adults With Fabry Disease
Fabry Disease
Phase 32021-12-28
CompletedPost Marketing Surveillance (PMS) Study for Velaglucerase Alfa (VPRIV) in India
Gaucher Disease
2021-07-28
WithdrawnARALAST NP Alpha-1 Lung Density Chronic Obstructive Pulmonary Disease-Emphysema (COPD-E) Study
Chronic Obstructive Pulmonary Disease, Alpha1-antitrypsin Deficiency
Phase 42021-03-08
CompletedRetrospective, Observational Chart Review Study Conducted in Poland to Document the Management and Clinical Ou
Primary Immunodeficiencies (PID)
2021-02-08
CompletedA Study of Long-Term Safety and Efficacy of Lanadelumab for Prevention of Acute Attacks of Non-histaminergic A
Angioedema
Phase 32021-02-05
CompletedA Study to Evaluate the Bioavailability of Teduglutide Administered Subcutaneously by Syringe Injection Versus
Healthy Volunteers
Phase 12021-01-13
WithdrawnLanadelumab in Participants Hospitalized With COVID-19 Pneumonia
COVID-19 Pneumonia
Phase 12020-10-31
CompletedA Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of a Single Oral Dose of Maribavir Administ
Healthy Volunteers
Phase 12020-08-07
CompletedEfficacy and Safety of Lanadelumab (SHP643) in Japanese Participants With Hereditary Angioedema (HAE)
Hereditary Angioedema (HAE)
Phase 32019-12-12
CompletedA Study of Lanadelumab in Persons With Hereditary Angioedema (HAE) Type I or II
Hereditary Angioedema (HAE)
2019-12-11
TerminatedA Study Comparing the Pharmacokinetics and Palatability of Two Candidate Pediatric Powder-for-Oral-Suspension
Healthy Volunteers
Phase 12019-10-25
CompletedA Study of SHP655 (rADAMTS13) in Sickle Cell Disease
Sickle Cell Disease
Phase 12019-10-21
CompletedStudy of rADAMTS-13 (SHP655) in the Treatment of Participants With Acquired Thrombotic Thrombocytopenic Purpur
Acquired Thrombotic Thrombocytopenic Purpura (aTTP)
Phase 22019-10-09
TerminatedA Study of VPRIV in Participants With Gaucher Disease Previously Treated With Other Enzyme Replacement Therapi
Gaucher Disease
2019-09-19
CompletedA Study of TAK-503 in Children and Teenagers With Attention Deficit Hyperactivity Disorder (ADHD)
Attention Deficit Hyperactivity Disorder
Phase 42019-09-18
CompletedA Study of Lanadelumab to Prevent Hereditary Angioedema (HAE) Attacks in Children
Hereditary Angioedema
Phase 32019-08-19
CompletedDrug Use Study With VYVANSE® in Australia for Binge Eating Disorder
Binge-eating Disorder
2019-06-01
CompletedA Study to Determine the Bioavailability of Lanadelumab (SHP643) Administered Subcutaneously With the Prefille
Healthy Volunteers
Phase 12019-05-14
Active Not RecruitingA Study of Intrathecal SHP611 in Children With Metachromatic Leukodystrophy
Metachromatic Leukodystrophy (MLD)
Phase 22019-05-13
CompletedA Study of Lanadelumab in Persons With Hereditary Angioedema (HAE) Type I or II in North America
Hereditary Angioedema (HAE)
2019-03-30
CompletedA Study to Assess the Safety, Tolerability, and Pharmacokinetics of Ascending, Subcutaneous, Single and Multip
Healthy Volunteers
Phase 12019-03-26
CompletedDrug Use Study With Intuniv® in Australia
Attention Deficit Hyperactivity Disorder (ADHD)
2019-03-11
CompletedStudy to Evaluate the Effect of Omeprazole on the Pharmacokinetics of SPD422 (Anagrelide Hydrochloride) in Hea
Healthy Volunteers
Phase 12019-02-26
TerminatedEfficacy and Safety Study of Ontamalimab as Maintenance Treatment in Participants With Moderate to Severe Croh
Crohn's Disease
Phase 32019-02-06
CompletedFIRAZYR General Drug Use-Results Survey (Japan)
Hereditary Angioedema (HAE)
2018-11-20
CompletedDrug Use Study With Intuniv® in European Countries
Attention Deficit Hyperactivity Disorder (ADHD)
2018-11-15
TerminatedSafety and Efficacy Study of rhPTH(1-84) in Subjects With Hypoparathyroidism
Hypoparathyroidism
Phase 32018-09-26
CompletedSafety, Efficacy and Pharmacokinetic Study of Teduglutide in Infants 4 to 12 Months of Age With Short Bowel Sy
Short Bowel Syndrome
Phase 32018-08-31
TerminatedEfficacy and Safety Study of Ontamalimab as Induction Therapy in Participants With Moderate to Severe Crohn's
Crohn's Disease
Phase 32018-08-29
TerminatedEfficacy and Safety Study of Ontamalimab as Induction Therapy in Participants With Moderate to Severe Crohn's
Crohn's Disease
Phase 32018-07-17
CompletedStudy of Teduglutide in Japanese Participants With Short Bowel Syndrome
Short Bowel Syndrome
Phase 32018-07-06
CompletedStudy of Midazolam Hydrochloride Oromucosal Solution (MHOS/SHP615) in Pediatric Patients With Status Epileptic
Nervous System Diseases
Phase 32018-04-23
CompletedAn Efficacy and Safety Study of Ontamalimab as Maintenance Therapy in Participants With Moderate to Severe Ulc
Ulcerative Colitis
Phase 32018-04-04
CompletedSafety, Tolerability and Pharmacokinetics of SHP465 in Children Aged 4 to 5 Years With Attention-Deficit/Hyper
Attention Deficit Hyperactivity Disorder (ADHD)
Phase 12018-03-13
CompletedA Safety Extension Study of Ontamalimab in Participants With Moderate to Severe Ulcerative Colitis or Crohn's
Crohn's Disease, Ulcerative Colitis
Phase 32018-02-27
TerminatedEfficacy and Safety Study of SHP647 as Induction Therapy in Participants With Moderate to Severe Ulcerative Co
Ulcerative Colitis
Phase 32018-02-09
CompletedA Study to Learn if Recombinant Human Parathyroid Hormone [rhPTH(1-84)] Can Improve Symptoms and Metabolic Con
Hypoparathyroidism
Phase 42018-01-24
CompletedIntensive Pharmacovigilance Program for Elaprase (SHP ELA-701)
Hunter Syndrome
2018-01-19
CompletedStudy of Lanadelumab in Healthy Japanese and Matched Caucasian Adult Subjects
Healthy Volunteers
Phase 12018-01-15
TerminatedSafety and Tolerability Study of SHP465 in Children Aged 4 to 12 Years Diagnosed With Attention-deficit/Hypera
Attention Deficit Hyperactivity Disorder (ADHD)
Phase 32018-01-02
CompletedEfficacy and Safety of SHP465 at 6.25 mg in the Treatment of Attention-Deficit/Hyperactivity Disorder (ADHD) i
Attention Deficit Hyperactivity Disorder (ADHD)
Phase 32017-12-09
TerminatedEfficacy and Safety Study of SHP647 as Induction Therapy in Participants With Moderate to Severe Ulcerative Co
Ulcerative Colitis
Phase 32017-12-05
CompletedOpen-label Study of Midazolam Hydrochloride Oromucosal Solution (MHOS/SHP615) in Children With Status Epilepti
Nervous System Diseases
Phase 32017-10-23
TerminatedContinuation Study With Budesonide Oral Suspension (BOS) for Adolescent and Adult Participants With Eosinophil
Eosinophilic Esophagitis (EoE)
Phase 32017-10-05
CompletedSafety and Efficacy Study in Preschool Children Aged 4-5 Years With Attention-deficit/Hyperactivity Disorder (
Attention Deficit Hyperactivity Disorder (ADHD)
Phase 32017-09-06
CompletedA Study in Japanese Children With Short Bowel Syndrome Who Completed SHP633-302
Short Bowel Syndrome
Phase 32017-08-23
CompletedStudy of rhPTH(1-84) in Japanese Healthy Subjects Compared With Matched Caucasian Healthy Adult Subjects
Hypoparathyroidism
Phase 12017-05-16
CompletedStudy of SHP639 Eye Drops in Adults With High Eye Pressure or Primary Open-angle Glaucoma
Primary Open-angle Glaucoma (POAG), Ocular Hypertension
Phase 12017-05-10
CompletedA Study of Maribavir Compared to Valganciclovir to Treat Cytomegalovirus Infections in People Who Have Receive
Cytomegalovirus (CMV)
Phase 32017-04-14
CompletedStudy to Assess the Blood Concentrations and Actions of Recombinant Human Parathyroid Hormone (rhPTH [1-84]) W
Hypoparathyroidism
Phase 12017-04-03
CompletedTreatment of Bacterial Conjunctivitis With SHP640 Compared to PVP-Iodine and Placebo
Bacterial Conjunctivitis
Phase 32017-03-29
TerminatedTreatment of Adenoviral Conjunctivitis With SHP640 Compared to Placebo
Adenoviral Conjunctivitis
Phase 32017-03-28
TerminatedTreatment of Adenoviral Conjunctivitis With SHP640 Compared to Povidone-iodine (PVP-I) and Placebo
Adenoviral Conjunctivitis
Phase 32017-03-27
TerminatedObservational Natural History Study of Autosomal Dominant Retinitis Pigmentosa (adRP)
Retinitis Pigmentosa
2017-03-13
CompletedStudy in Japanese Pediatric Subjects With Short Bowel Syndrome (SBS) Who Are Dependent on Parenteral Support
Short Bowel Syndrome
Phase 32017-01-13
CompletedLong-term Safety and Efficacy Study of Teduglutide in Pediatric Participants With Short Bowel Syndrome (SBS)
Short Bowel Syndrome
Phase 32017-01-09
CompletedEfficacy and Safety Study of Maribavir Treatment Compared to Investigator-assigned Treatment in Transplant Rec
Cytomegalovirus (CMV)
Phase 32016-12-22
CompletedLong-term Study of Teduglutide in Pediatric Subjects With Short Bowel Syndrome Who Completed the TED-C13-003 S
Short Bowel Syndrome
Phase 32016-12-09
CompletedA Study of Extended Use of Recombinant Human Parathyroid Hormone (rhPTH(1-84)) in Hypoparathyroidism
Chronic Hypoparathyroidism, Hypoparathyroidism
Phase 42016-10-27
CompletedStudy of C1 Inhibitor (Human) for the Prevention of Angioedema Attacks and Treatment of Breakthrough Attacks i
Hereditary Angioedema (HAE)
Phase 32016-09-08
CompletedTHIN Database Study: Resource Use and Outcomes in Patients With Adrenal Insufficiency Prescribed Hydrocortison
Adrenal Insufficiency
2016-09-01
CompletedStudy of SHP620 (Maribavir) in Healthy Adults
Cytomegalovirus (CMV)
Phase 12016-07-21
CompletedStudy of the Effect of Velaglucerase Alfa (VPRIV®) on Bone-related Pathology in Treatment-naïve Participants W
Gaucher Disease
Phase 42016-06-29
CompletedShort Bowel Syndrome Research Study for Children Up To 17 Years of Age on Parenteral Nutrition
Short Bowel Syndrome
Phase 32016-06-23
CompletedLong-term Safety and Efficacy Study of DX-2930 (SHP643) to Prevent Acute Angioedema Attacks in Patients With T
Hereditary Angioedema (HAE)
Phase 32016-05-26
TerminatedA Multicenter Study to Evaluate the Efficacy and Safety of Cinryze® for the Treatment of Acute Antibody-mediat
Acute Antibody-Mediated Rejection (AMR)
Phase 32016-05-20
CompletedAn Extension Study to Evaluate Maintenance of Efficacy and Long-term Treatment Effect of Oral Budesonide Suspe
Eosinophilic Esophagitis (EoE)
Phase 32016-04-01
CompletedEfficacy and Safety Study of DX-2930 to Prevent Acute Angioedema Attacks in Patients With Type I and Type II H
Hereditary Angioedema (HAE)
Phase 32016-03-03
CompletedPhase 1 Study to Assess the Safety, Tolerability, and Pharmacokinetics of Recombinant Human C1 Esterase Inhibi
Hereditary Angioedema (HAE)
Phase 12016-02-19
CompletedA Study in Adolescents and Adults With Eosinophilic Esophagitis (EoE) Measuring Histologic Response and Determ
Eosinophilic Esophagitis (EoE)
Phase 32015-12-07
CompletedSafety and Efficacy Study of SHP465 in Adults Aged 18-55 Years With Attention-deficit/ Hyperactivity Disorder
Attention Deficit Hyperactivity Disorder (ADHD)
Phase 32015-11-19
TerminatedNatural History Study of Children With Metachromatic Leukodystrophy
Lipid Metabolism Disorders, Metachromatic Leukodystrophy (MLD), Nervous System Diseases
2015-11-02
CompletedStudy to Evaluate the Clinical Efficacy and Safety of Subcutaneously Administered C1 Esterase Inhibitor for th
Hereditary Angioedema (HAE)
Phase 32015-11-01
CompletedLong-term Evaluation on Height and Weight in Patients With MPS II Who Started Treatment at < 6 Years of Age
Hunter Syndrome
Phase 42015-10-28
CompletedPharmacokinetic Study in Children and Adolescents Aged 6 to 17 Years Who Have Been Diagnosed With ADHD
Attention Deficit Hyperactivity Disorder (ADHD)
Phase 12015-10-24
CompletedA Survey to Assess Participants' and Physicians' Knowledge, Attitudes and Behavior When Using NATPARA
Hypoparathyroidism
2015-09-01
CompletedSafety and Tolerability Study of SPD489 in Preschool Children Aged 4-5 Years, Diagnosed With Attention-deficit
Attention Deficit Hyperactivity Disorder (ADHD)
Phase 32015-08-21
CompletedSafety and Efficacy Study of SHP465 in Children and Adolescents Aged 6-17 Years With Attention-Deficit Hyperac
Attention Deficit Hyperactivity Disorder (ADHD)
Phase 32015-06-18
CompletedSafety, Tolerability, Pharmacokinetic, and Efficacy Study of SPD489 in Preschool Children With Attention-defic
Attention Deficit Hyperactivity Disorder (ADHD)
Phase 22015-04-15
CompletedStudy of Long Term Safety and Clinical Outcomes of Idursulfase IT and Elaprase Treatment in Pediatric Particip
Hunter Syndrome
Phase 2 / Phase 32015-04-14
TerminatedAn Extension Study to Determine Safety and Efficacy for Pediatric Patients With MPS Type IIIA Disease Who Part
Sanfilippo Syndrome, Mucopolysaccharidosis (MPS)
Phase 22015-04-08
CompletedLong-term Safety and Efficacy Outcome Study Comparing Children Previously Enrolled in Study ROPP-2008-01 for t
Retinopathy of Prematurity (ROP)
Phase 22015-03-26
CompletedA Study of Icatibant for Acute Attacks of Hereditary Angioedema in Japanese Participants
Hereditary Angioedema (HAE)
Phase 32015-03-18
CompletedStudy to Evaluate the Safety, Efficacy and Pharmacokinetics of Teduglutide in Japanese Subjects With PN-depend
Short Bowel Syndrome
Phase 32014-12-18
CompletedSafety and Efficacy of MMX Mesalamine/Mesalazine in Pediatric Subjects With Mild to Moderate Ulcerative Coliti
Ulcerative Colitis
Phase 32014-12-12
WithdrawnTreatment of Iron Overload Requiring Chelation Therapy
Transfusional Iron Overload, Iron Overload, Iron Chelation
Phase 22014-11-20
CompletedA Study to Evaluate Efficacy and Safety of Lifitegrast in Subjects With Dry Eye (OPUS-3)
Dry Eye Disease
Phase 32014-11-06
CompletedA Study to Determine the Effects of NPSP795 on the Calcium-sensing Receptor in Subjects With Autosomal Dominan
Autosomal Dominant Hypocalcemia (ADH)
Phase 22014-07-18
CompletedShort Term Observational Study in DEB Patients
Dystrophic Epidermolysis Bullosa
2014-06-24
Active Not RecruitingRegistry for Participants With Short Bowel Syndrome
Short Bowel Syndrome
2014-06-23
CompletedTaste Assessment Study of SHP429 in Healthy Adult Subjects
Healthy
Phase 12014-06-02
TerminatedMucopolysaccharidosis (MPS) I, II, and VI Screening in a High-Risk Population With Previous Surgical Repair or
Mucopolysaccharidosis (MPS)
2014-05-21
CompletedA Double-Blind, Multiple Ascending Dose Study to Assess Safety, Tolerability and Pharmacokinetics of DX-2930 i
Hereditary Angioedema (HAE)
Phase 12014-05-14
CompletedStudy of Intrathecal Idursulfase-IT Administered in Conjunction With Elaprase® in Pediatric Patients With Hunt
Hunter Syndrome
Phase 2 / Phase 32014-03-24
CompletedSafety and Efficacy Study of CINRYZE for Prevention of Angioedema Attacks in Children Ages 6-11 With Hereditar
Hereditary Angioedema (HAE)
Phase 32014-03-20
WithdrawnPharmacokinetics of Granule and Tablet Formulations of Deferitazole (Disodium Salt) and a Capsule Formulation
Healthy
Phase 12014-02-28
CompletedRandomized, Controlled, Open-label, Multicenter, Safety and Efficacy Study of rhHNS Administration Via an IDDD
Sanfilippo Syndrome
Phase 22014-02-26
CompletedOpen-label, Single-arm Study to Assess the Pharmacokinetics, Safety, and Tolerability of a Single Subcutaneous
Hereditary Angioedema (HAE)
Phase 12014-02-21
CompletedEvaluate the Maintenance of Efficacy of SPD489 in Adults Aged 18-55 Years With Moderate to Severe Binge Eating
Binge Eating Disorder
Phase 32014-01-27
CompletedBlinded Safety & Efficacy Placebo Controlled Study of Icatibant for Angiotensin Converting Enzyme Inhibitor In
Angiotensin Converting Enzyme Inhibitor Induced Angioedema
Phase 32013-12-02
CompletedPharmacokinetic Interaction Between SSP-004184 (SPD602) and Midazolam in Healthy Adult Subjects
Healthy
Phase 12013-11-26
CompletedEffect of SSP-004184 (SPD602) on the Pharmacokinetics of Simvastatin in Healthy Adult Subjects
Healthy
Phase 12013-11-18
CompletedA Pharmacokinetic, Safety, and Pharmacodynamic Study of Teduglutide in Pediatric Subjects With Short Bowel Syn
Short Bowel Syndrome
Phase 32013-11-14
CompletedThe Effect of Food on the Bioavailability of a Single Dose of SSP-004184SS in Healthy Adult Subjects
Healthy
Phase 12013-08-27
CompletedSafety and Pharmacology Study of VP 20629 in Adults With Friedreich's Ataxia
Friedreich's Ataxia
Phase 12013-08-13
CompletedA Single Increasing Dose Study to Assess Safety and Tolerability of DX-2930 in Healthy Subjects
Hereditary Angioedema (HAE)
Phase 12013-08-12
CompletedA Relative Bioavailability Study of SSP-004184AQ (Magnesium Salt) and SSP-004184SS (Disodium Salt)
Healthy
Phase 12013-08-05
CompletedBioavailability Study of SPD489 Administered With Two Different Means of Administration in Healthy Adult Volun
Healthy Volunteers
Phase 12013-07-15
Active Not RecruitingAn Efficacy and Safety Study of HGT-1110 in Participants With Metachromatic Leukodystrophy
Metachromatic Leukodystrophy (MLD)
Phase 1 / Phase 22013-05-23
CompletedFST-100 in the Treatment of Acute Viral Conjunctivitis
Acute Viral Conjunctivitis
Phase 22013-05-17
CompletedAME (Absorption, Metabolism, and Excretion) of Radiolabeled SSP-004184
Healthy
Phase 12013-05-01
TerminatedAn Efficacy and Safety Study of SRM003 in the Treatment of Subjects Undergoing Placement of an Arteriovenous G
Arteriovenous Graft
Phase 22013-03-28
CompletedAn Efficacy and Safety Study of SRM003 in the Treatment of Subjects Undergoing Creation of an Arteriovenous Fi
Arteriovenous Fistula
Phase 22013-03-26
CompletedLong-Term Safety Of PF-00547659 In Ulcerative Colitis
Ulcerative Colitis
Phase 22013-03-18
CompletedAbsorption, Metabolism and Excretion (AME) of Single Dose Radiolabeled Prucalopride Succinate in Volunteers
Healthy
Phase 12013-03-18
CompletedMulticenter Extension Study of Velaglucerase Alfa in Japanese Patients With Gaucher Disease
Gaucher Disease
Phase 32013-03-13
CompletedAdsorption, Metabolism and Excretion (AME) of Single Dose Radiolabeled SPD557 in Volunteers
Healthy Volunteers
Phase 12013-03-07
CompletedStudy to Investigate Prucalopride vs. Polyethylene Glycol 3350 on Colon Activity
Chronic Constipation
Phase 42013-02-27
CompletedA Study to Assess the Pharmacokinetics of Lanthanum Carbonate, Investigate and Compare the Efficacy, Safety an
Chronic Kidney Disease, Hyperphosphatemia
Phase 22013-02-15
CompletedSubcutaneous CINRYZE With Recombinant Human Hyaluronidase for Prevention of Angioedema Attacks
Hereditary Angioedema (HAE)
Phase 22013-02-04
TerminatedLong-term Safety of SPD489 When Added to Stable Doses of Antipsychotic Medications in Clinically Stable Adults
Schizophrenia
Phase 32013-02-01
TerminatedSPD489 Low Dose and High Dose Ranges When Added to Stable Doses of Antipsychotic Medications in Clinically Sta
Schizophrenia
Phase 32013-02-01
CompletedObservational Study to Evaluate Neurodevelopmental Status in Pediatric Patients With Hunter Syndrome (MPS II)
Mucopolysaccharidosis (MPS), Hunter Syndrome
2013-01-18
CompletedFST-100 in the Treatment of Acute Adenoviral Conjunctivitis
Acute Adenoviral Conjunctivitis
Phase 22012-12-17
CompletedA Phase 3 Study to Evaluate the Efficacy of Lifitegrast in Subjects With Dry Eye
Dry Eye Disease
Phase 32012-12-07
CompletedSPD489 in Adults Aged 18-55 Years With Moderate to Severe Binge Eating Disorder
Binge Eating Disorder
Phase 32012-11-26
CompletedSPD489 in Adults Aged 18-55 Years With Moderate to Severe Binge Eating Disorder
Binge Eating Disorder
Phase 32012-11-26
CompletedCollection and Study of Cerebrospinal Fluid in Patients With Hunter Syndrome
Hunter Syndrome
2012-11-12
CompletedStudy of SSP-004184 (SPD602) in Healthy Adults and Subjects With Impaired Liver Function
Hepatic Impairment, Healthy
Phase 12012-11-09
CompletedA Study Of PF-00547659 In Patients With Moderate To Severe Ulcerative Colitis
Ulcerative Colitis
Phase 22012-11-02
TerminatedAdjunctive SPD489 to Antipsychotic Medication in Clinically Stable Adults With Persistent Predominant Negative
Schizophrenia
Phase 32012-11-01
CompletedStudy of SSP-004184 (FBS0701) in Healthy Adults and Elderly Subjects and in Subjects With Impaired Renal Funct
Impaired Renal Function
Phase 12012-10-29
CompletedSafety Study of Lifitegrast to Treat Dry Eye
Dry Eye Disease
Phase 32012-10-16
CompletedEfficacy and Safety Study of Velaglucerase Alfa in Children and Adolescents With Type 3 Gaucher Disease
Gaucher Disease, Type 3
Phase 1 / Phase 22012-09-14
TerminatedPharmacokinetics of SSP-004184 in the Treatment of Chronic Iron Overload Requiring Chelation Therapy
Iron Overload Due to Repeated Red Blood Cell Transfusions
Phase 22012-09-14
CompletedOpen Label Extension in Adults With Binge Eating Disorder (BED)
Binge Eating Disorder
Phase 32012-08-21
TerminatedStudy for Transfusionally Iron Overloaded Children, Adolescents and Adults Using FBS0701 (SSP-004184)
Iron Overload Due to Repeated Red Blood Cell Transfusions
Phase 22012-08-14
TerminatedA European Post-Authorisation Observational Study (Registry) of Patients With Chronic Adrenal Insufficiency (A
Chronic Adrenal Insufficiency
2012-08-07
CompletedOBS in Adolescent and Adults With EOE: A Phase II, Randomized, Double-Blind, Placebo Controlled, Study With an
Eosinophilic Esophagitis (EoE)
Phase 22012-07-23
CompletedMaribavir for Treatment of Resistant or Refractory CMV Infections in Transplant Recipients
Cytomegalovirus (CMV)
Phase 22012-07-17
WithdrawnStudy to Evaluate Ecallantide in Paediatric Patients With Acute Attacks of Hereditary Angioedema
Hereditary Angioedema (HAE)
Phase 2 / Phase 32012-06-01
CompletedClinical Efficacy of Midodrine in Symptomatic Orthostatic Hypotension
Symptomatic Orthostatic Hypotension
Phase 42012-05-23
CompletedA One-Year, Open-Label Study With Teduglutide for Subjects Who Completed Study CL0600-021
Short Bowel Syndrome
Phase 32012-05-21
CompletedTilt-Table Study of the Clinical Efficacy of Midodrine in Symptomatic Orthostatic Hypotension
Orthostatic Hypotension
Phase 42012-05-14
CompletedA European Post-Authorisation Observational Study Of Patients With Hereditary Angioedema
Hereditary Angioedema (HAE)
2012-05-11
CompletedEvaluate PF-00547659 On Cerebrospinal Fluid Lymphocytes In Volunteers With Crohn's Disease Or Ulcerative Colit
Crohn's Disease, Ileitis, Ileo-colonic and Colonic Crohn's Disease
Phase 12012-05-03
CompletedEffectiveness of Vyvanse Compared to Concerta in Adolescents With Attention-deficit/Hyperactivity Disorder
Attention-deficit/Hyperactivity Disorder
Phase 42012-04-17
CompletedNatural History Study of Patients With Mucopolysaccharidosis Type IIIB (MPS IIIB, Sanfilippo Syndrome Type B)
Sanfilippo Syndrome Type B
2012-04-09
CompletedEffectiveness of Vyvanse Compared to Concerta in Adolescents With Attention-deficit/Hyperactivity Disorder
Attention-deficit/Hyperactivity Disorder
Phase 42012-04-03
CompletedEffect of Anagrelide Hydrochloride on Any Changes in Heart Function in Healthy Volunteers
Healthy
Phase 12012-03-29
CompletedAccess to Extended Release Guanfacine HCl for Subjects Who Participated in Studies SPD503-315 or SPD503-316 in
Attention Deficit Hyperactivity Disorder (ADHD)
Phase 32012-03-20
CompletedStudy of Velaglucerase Alfa Enzyme Replacement Therapy in Japanese Patients With Gaucher Disease
Gaucher Disease
Phase 32012-03-02
TerminatedSPD489 Adult Major Depressive Disorder (MDD) Open-label Safety and Tolerability Rollover Extension Study
Major Depressive Disorder
Phase 32012-02-27
CompletedSelective 5-HT4 Receptor Agonist and Proton Pump Inhibitor (PPI) in Subjects With Gastroesophageal Reflux Dise
Gastroesophageal Reflux Disease
Phase 22012-02-27
CompletedMulticenter Study of HGT-1110 Administered Intrathecally in Children With Metachromatic Leukodystrophy (MLD)
Metachromatic Leukodystrophy (MLD)
Phase 1 / Phase 22012-02-02
WithdrawnSPD489 as Adjunctive Treatment in Adults With Negative Symptoms of Schizophrenia
Negative Symptoms of Schizophrenia
Phase 32012-01-27
CompletedA Pharmacokinetic, Tolerability and Safety Study of Icatibant in Children and Adolescents With Hereditary Angi
Hereditary Angioedema (HAE)
Phase 32012-01-27
CompletedSPD503 in Subjects Aged 6-17 Years With Generalized Anxiety Disorder (GAD), Separation Anxiety Disorder (SAD),
Generalized Anxiety Disorder (GAD), Anxiety, Separation, Phobia, Social
Phase 22012-01-04
CompletedThis Study is Designed to Evaluate PD/PK and Safety of Replagal Manufactured by Two Different Processes.
Fabry Disease
Phase 22011-11-17
CompletedSulfamethoxazole Drug Interaction Study With MMX® Mesalazine/Mesalamine
Healthy
Phase 12011-11-07
CompletedEfficacy and Safety Study of SPD489 in Combination With an Antidepressant in the Treatment of Adults With Majo
Major Depressive Disorder
Phase 32011-10-27
CompletedAssess the Safety and Pharmacokinetics of Ascending, Multiple Oral Doses of SPD489 in Adults With Schizophreni
Schizophrenia
Phase 12011-10-21
CompletedEfficacy and Safety Study of SPD489 in Combination With an Antidepressant in the Treatment of Adults With Majo
Major Depressive Disorder
Phase 32011-10-19
CompletedAmoxicillin Drug Interaction Study With MMX® Mesalazine/Mesalamine
Healthy
Phase 12011-10-07
CompletedDose-optimization in Adolescents Aged 13-17 Diagnosed With Attention-deficit/Hyperactivity Disorder (ADHD) Usi
Attention-Deficit/Hyperactivity Disorder
Phase 32011-09-19
CompletedA Study to Evaluate the Safety and Pharmacology of Subcutaneous Administration of CINRYZE With Recombinant Hum
Hereditary Angioedema
Phase 22011-09-12
CompletedSafety and Efficacy Study of SAR 1118 to Treat Dry Eye Conducted in a Controlled Adverse Environment (CAE) (OP
Keratoconjunctivitis Sicca, Dry Eye Disease
Phase 32011-08-29
CompletedA Pilot Study to Evaluate the Use of C1 Esterase Inhibitor (Human) in Patients With Acute Antibody-Mediated Re
Graft Rejection
Phase 22011-08-24
CompletedMetronidazole Drug Interaction Study With MMX® Mesalazine/Mesalamine
Healthy
Phase 12011-08-22
CompletedA Study to Investigate the Safety and Tolerability of NPSP558, for the Treatment of Adults With Hypoparathyroi
Hypoparathyroidism
Phase 32011-08-19
CompletedSSP-002358 Drug Interaction Study With Omeprazole
Healthy
Phase 12011-08-11
TerminatedSafety, Efficacy and Pharmacokinetics of an Oral Iron Chelator Given for a Year to Pediatric Patients With Iro
Transfusional Iron Overload, Beta-Thalassemia
Phase 22011-08-10
CompletedA Multicenter Open-Label Treatment Protocol to Observe the Safety of Replagal (Agalsidase Alfa) Enzyme Replace
Fabry Disease
Phase 32011-08-10
CompletedCiprofloxacin XR Drug Interaction Study With MMX® Mesalazine/Mesalamine
Healthy
Phase 12011-07-25
CompletedExploratory Multi-centre Trial In Patients With ET Treated With XAGRID®
Essential Thrombocythemia (ET)
2011-07-19
CompletedLisdexamfetamine Dimesylate 2-year Safety Study in Children and Adolescents With Attention-Deficit/Hyperactivi
Attention Deficit Hyperactivity Disorder (ADHD)
Phase 42011-07-07
CompletedA Study To Monitor Long-Term Treatment With PF-00547659
Crohn's Disease
Phase 22011-07-01
CompletedSafety and Efficacy Study of VP20621 for Prevention of Recurrent Clostridium Difficile Infection
Clostridium Difficile Infection
Phase 22011-06-27
TerminatedEvaluation of Ecallantide for Treatment of Angiotensin Converting Enzyme (ACE) Inhibitor Induced Angioedema
ACE Inhibitor Induced Angioedema
Phase 22011-06-01
CompletedSPD489 in Combination With an Antidepressant in the Treatment of Adults With Major Depressive Disorder
Major Depressive Disorder
Phase 22011-05-31
CompletedHome Therapy With VPRIV in Gaucher's Disease
Gaucher Disease
2011-05-20
CompletedSafety Study of Replagal® Therapy in Children With Fabry Disease
Fabry Disease
Phase 22011-05-12
CompletedForced-dose Titration of SPD489 in Adults With Binge Eating Disorder
Binge Eating Disorder
Phase 22011-05-10
CompletedPrucalopride in Pediatric Subjects With Functional Constipation
Functional Constipation
Phase 32011-04-28
CompletedStudy To Test Whether PF-00547659 Is Safe And Improves Disease Symptoms In Patients With Crohn's Disease
Crohn's Disease
Phase 22011-04-06
CompletedA Open-label Study Investigating the Safety and Tolerability of NPSP558, a Recombinant Human Parathyroid Hormo
Hypoparathyroidism
Phase 32011-04-06
CompletedEvaluation of Long-term Prucalopride Treatment With Chronic Constipation in Subjects Aged ≥ 18 Years
Constipation
Phase 42011-04-06
CompletedHome Therapy With Replagal in Fabry Disease
Fabry Disease
2011-03-15
WithdrawnSafety and Efficacy of SPD489 in Adolescent Subjects Aged 13-17 Years With Attention-Deficit/Hyperactivity Dis
ADHD
Phase 32011-03-06
TerminatedExtension of Study HGT-SAN-055 Evaluating Administration of rhHNS in Patients With Sanfilippo Syndrome Type A
Sanfilippo Syndrome
Phase 1 / Phase 22011-03-01
CompletedStudy of Safety and Efficacy of a rhPTH[1-84] of Fixed Doses of 25 and 50 mcg in Adults With Hypoparathyroidis
Hypoparathyroidism
Phase 32011-02-09
CompletedEfficacy and Safety of Extended-release Guanfacine Hydrochloride in Children and Adolescents Aged 6-17 Years W
Attention Deficit Hyperactivity Disorder
Phase 32011-01-17
CompletedEffects of Lanthanum Carbonate on FGF-23 in Subjects With Stage 3 CKD
Chronic Kidney Disease
Phase 22010-12-06
TerminatedAn Explorative Trial to Evaluate the Pharmacodynamic Effect of SPD557 on Reflux Parameters in Refractory GERD
Gastroesophageal Reflux Disease
Phase 22010-12-02
CompletedSophisticated Assessment of Disease Burden in Patients With Fabry Disease
Fabry Disease
2010-10-31
CompletedCo-Administration of LDX (SPD489) and Venlafaxine XR (EFFEXOR XR) in Healthy Volunteers
Healthy
Phase 12010-10-28
CompletedEffect of SPD422 on Platelet Lowering and Safety in Japanese Adults With At Risk Essential Thrombocythaemia
Essential Thrombocythemia (ET)
Phase 32010-10-27
CompletedLong-term Safety of SPD422 in Japanese Adults With Essential Thrombocythaemia
Essential Thrombocythemia (ET)
Phase 32010-10-27
CompletedSafety and Pharmacokinetics of MMX Mesalamine in Children and Adolescents With Ulcerative Colitis
Ulcerative Colitis
Phase 12010-10-08
CompletedPediatric Disease Registry in Essential Thrombocythaemia (ET)
Essential Thrombocythemia (ET)
2010-09-28
CompletedEffect of Teduglutide on Gastric Emptying in Healthy Subjects
Healthy Volunteers
Phase 12010-09-28
CompletedEvaluation of Prucalopride in Male Subjects With Chronic Constipation.
Male Subjects With Chronic Constipation
Phase 32010-09-23
CompletedFrench Observational Xagrid (FOX) Study In Adult Patients With Essential Thrombocythemia
Essential Thrombocythemia
2010-09-13
CompletedSPD544 High Strength Bioequivalence Study
ADHD
Phase 12010-08-27
CompletedSafety and Pharmacodynamic Study of an Oral Iron Chelator Given for 6 Months to Patients With Iron Overload
Transfusional Iron Overload, Beta-thalassemia
Phase 22010-08-13
RecruitingGaucher Disease Outcome Survey (GOS)
Gaucher Disease
2010-07-27
CompletedAbility to Maintain or Achieve Clinical and Endoscopic Remission With MMX Mesalamine Once Daily in Adults With
Ulcerative Colitis
Phase 42010-06-29
CompletedComparison of Lisdexamfetamine Dimesylate With Atomoxetine HCl in Attention-Deficit/Hyperactivity Disorder (AD
Attention-Deficit/Hyperactivity Disorder
Phase 32010-06-28
CompletedIGF-1/IGFBP3 Prevention of Retinopathy of Prematurity
Retinopathy of Prematurity (ROP)
Phase 22010-06-18
CompletedA Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of Subcutaneous CINRYZE Administration
Hereditary Angioedema
Phase 22010-06-07
CompletedCINRYZE for the Treatment of Hereditary Angioedema Attacks in Children Under the Age of 12
Hereditary Angioedema (HAE)
Phase 22010-06-02
CompletedSafety, Tolerability, Ascending Dose and Dose Frequency Study of rhHNS Via an IDDD in MPS IIIA Patients
Mucopolysaccharidosis (MPS)
Phase 1 / Phase 22010-06-01
TerminatedPrucalopride Effects on Subjects With Chronic Non-cancer Pain Suffering From Opioid Induced Constipation
Non-cancer Pain, Opioid Induced Constipation
Phase 32010-05-19
CompletedSafety and Efficacy of SPD489 on Executive Function Behaviors in Adults With Attention-Deficit/Hyperactivity D
ADHD Specifically With Executive Function Impairment
Phase 42010-05-19
CompletedMaintenance of Efficacy of Extended-Release Guanfacine HCl in Children and Adolescents With Attention-deficit/
Attention-deficit/Hyperactivity Disorder
Phase 32010-05-11
CompletedStudy of PVS-10200 for the Treatment of Restenosis in Patients With Peripheral Artery Disease (TRIUMPH)
Peripheral Artery Disease
Phase 1 / Phase 22010-04-30
CompletedEffect of Lanthanum Carbonate in Patients Previously Treated With Calcium-based Phosphate Binder Therapy
End Stage Renal Disease
2010-04-26
CompletedExtension Study of TKT028 Evaluating Safety and Clinical Outcomes of Replagal® in Adult Patients With Fabry Di
Fabry Disease
Phase 32010-04-13
CompletedPharmacodynamic Profile of SPD489 in Healthy Adult Males Undergoing a Nocturnal Period of Acute Sleep Loss
Sleep Deprivation
Phase 22010-04-05
WithdrawnAn Observational Study of Pediatric Subjects With Globoid Cell Leukodystrophy (GLD)
Leukodystrophy, Globoid Cell
2010-04-01
CompletedA Study of Patients With Sanfilippo Syndrome Type A (MPS IIIA)
Sanfilippo Syndrome Type A
2010-02-15
CompletedObservational Safety Study for KALBITOR (Ecallantide) in the Treatment of Acute Attacks of Hereditary Angioede
Hereditary Angioedema (HAE)
2010-02-01
CompletedLisdexamfetamine Dimesylate (LDX) Pilot Cognition Study to Evaluate the Utility of a Standardized Battery of T
Attention-Deficit Hyperactivity Disorder
Phase 12010-01-05
CompletedA Safety and Dose Ranging Study of Idursulfase (Intrathecal) Administration Via an Intrathecal Drug Delivery D
Hunter Syndrome
Phase 1 / Phase 22009-11-18
CompletedTolerability and Efficacy of AM and PM Once Daily Dosing With Extended-release Guanfacine Hydrochloride in Chi
Attention-Deficit/Hyperactivity Disorder
Phase 32009-11-17
CompletedSPD489 in Adults With Persistent Executive Function Impairments (EFI) and Partial or Full Remission of Recurre
Major Depressive Disorder
Phase 22009-10-29
CompletedEASSI - Evaluation of the Safety of Self-Administration With Icatibant
Hereditary Angioedema
Phase 32009-09-25
CompletedOpen-Label Study of Teduglutide for Subjects With PN-Dependent Short Bowel Syndrome (SBS)
Short Bowel Syndrome
Phase 32009-09-21
CompletedEfficacy, Safety, and Tolerability of SPD489 in Adults With Schizophrenia and Predominant Negative Symptoms
Schizophrenia and Predominant Negative Symptoms
Phase 22009-09-14
CompletedFST-201 in the Treatment of Acute Otitis Externa
Acute Otitis Externa
Phase 32009-08-31
CompletedA Study to Evaluate the Safety and Effect of Escalating Doses of CINRYZE
Hereditary Angioedema
Phase 42009-08-31
CompletedA Study Evaluating the Efficacy of SAR 1118 (0.1%, 1.0%, 5.0%) Ophthalmic Solution in Subjects With Dry Eye Co
Dry Eye
Phase 22009-08-03
TerminatedFST-201 In The Treatment of Acute Fungal Otitis Externa
Acute Fungal Otitis Externa
Phase 32009-07-31
TerminatedFST-201 In The Treatment of Acute Otitis Externa
Acute Otitis Externa
Phase 32009-07-31
CompletedExploratory Study of SPD489 in Adults With Major Depressive Disorder (MDD) as Augmentation Therapy to an Antid
Major Depressive Disorder
Phase 22009-07-30
CompletedA Study of Icatibant in Patients With Acute Attacks of Hereditary Angioedema (FAST-3)
Hereditary Angioedema
Phase 32009-07-16
CompletedFirazyr® Patient Registry (Icatibant Outcome Survey - IOS)
Hereditary Angioedema (HAE)
2009-07-10
CompletedScreening Study to Identify Pediatric Patients With Hunter Syndrome Who Demonstrate Evidence of Central Nervou
Hunter Syndrome
2009-07-02
TerminatedFST-100 Ophthalmic Suspension in Acute Adenoviral Conjunctivitis
Acute Adenoviral Conjunctivitis
Phase 22009-06-30
CompletedA Drug Interaction Study of SPD503 and Vyvanse Administered Alone and In Combination in Normal Healthy Volunte
Healthy
Phase 12009-06-24
CompletedThe Pharmacokinetics of Rocaltrol When Administered Alone or in Combination With Fosrenol or Renvela in Health
Healthy
Phase 12009-06-01
CompletedA Drug Interaction Study of SPD503 and Concerta Administered Alone and In Combination in Normal Healthy Volunt
Healthy
Phase 12009-05-18
CompletedSafety and Efficacy of Vyvanse in Adults With Attention-Deficit/Hyperactivity Disorder
Attention-Deficit/Hyperactivity Disorder
Phase 42009-04-30
CompletedEfficacy Study to Evaluate the Effectiveness of 3 Concentrations of SAR 1118 in Allergic Conjunctivitis
Allergic Conjunctivitis
Phase 22009-04-24
CompletedComparing Absorption of Dietary Phosphorus When Administering FOSRENOL® or RENVELA® in Healthy Adult Volunteer
Kidney Failure, Chronic
Phase 12009-04-20
CompletedPharmacodynamic Study of Two Lanthanum Carbonate Formulations in Healthy Adults
End Stage Renal Disease
Phase 12009-01-28
CompletedDouble-blind, Placebo-controlled, Randomised Withdrawal, Extension, Safety and Efficacy Study of LDX in Childr
ADHD
Phase 32009-01-27
CompletedDose-Ranging Study of Oral Viscous Budesonide in Pediatrics With Eosinophilic Esophagitis
Eosinophilic Esophagitis (EoE)
Phase 22009-01-08
CompletedSafety and Efficacy Study of Several Replagal Dosing Regimens on Cardiac Function in Adults With Fabry Disease
Fabry Disease
Phase 32008-12-29
CompletedUse of NPSP558 in the Treatment of Hypoparathyroidism
Hypoparathyroidism
Phase 32008-12-18
CompletedStudy of Teduglutide Effectiveness in Parenteral Nutrition (PN)-Dependent Short Bowel Syndrome (SBS) Subjects
Short Bowel Syndrome
Phase 32008-11-25
TerminatedCompare Subjective Drug Liking & Pharmacokinetics of Vyvanse™ and ADDERALL XR® When Administered as an Oral So
Healthy
Phase 12008-11-21
CompletedRandomized, Double-blind Safety and Efficacy Study of Lisdexamfetamine Dimesylate (LDX) in Children and Adoles
ADHD
Phase 32008-11-17
CompletedVyvanse Adolescent Open-Label Safety and Efficacy Extension Study
ADHD
Phase 32008-11-13
CompletedAn Observational Study Evaluating Anti-Idursulfase Serum Antibody Response in Hunter Syndrome Patients
Hunter Syndrome
2008-10-14
CompletedEfficacy and Safety of Lisdexamfetamine Dimesylate (LDX) in Adolescents With Attention-Deficit/Hyperactivity D
Attention Deficit Hyperactivity Disorder (ADHD)
Phase 32008-10-08
CompletedVyvanse and Adderall XR Given Alone and in Combination With Prilosec OTC
Healthy Volunteers
Phase 12008-09-08
CompletedEfficacy and Safety of SPD503 in Combination With Psychostimulants
ADHD
Phase 32008-09-02
CompletedSafety and Efficacy Workplace Environment Study of Lisdexamfetamine Dimesylate (LDX) in Adults With Attention-
ADHD
Phase 32008-07-18
TerminatedDELFT (Dynepo Evaluation of Long-Term Follow-Up Treatment)
Anemia, Kidney Diseases, Renal Failure, Chronic
2008-04-25
CompletedGuanfacine Immediate-release Electrocardiogram Results (QTc) Study
Healthy Volunteers
Phase 12008-04-18
CompletedAn Open-Label Extension Study of GA-GCB ERT in Patients With Type 1 Gaucher Disease
Gaucher Disease, Type 1
Phase 32008-03-13
TerminatedOpen-Label Extension Study of Recombinant Human Arylsulfatase A (HGT-1111) in Late Infantile MLD
Late Infantile Metachromatic Leukodystrophy
Phase 22008-02-20
CompletedStudy of Gene-Activated® Human Glucocerebrosidase (GA-GCB) ERT Compared With Imiglucerase in Type I Gaucher Di
Gaucher Disease, Type 1
Phase 32008-01-29
CompletedSafety and Clinical Outcomes in Hunter Syndrome Patients 5 Years of Age and Younger Receiving Idursulfase Ther
Hunter Syndrome, Mucopolysaccharidosis II, MPS II
Phase 42007-12-31
CompletedPrevention of Recurrence of Diverticulitis
Diverticulitis
Phase 32007-12-06
CompletedPrevention of Recurrence of Diverticulitis
Diverticulitis
Phase 32007-11-28
CompletedOnce-daily Oral Modified Release Hydrocortisone in Patients With Adrenal Insufficiency
Adrenal Insufficiency
Phase 2 / Phase 32007-08-21
CompletedPharmacokinetics (PK) of 20 mg Teduglutide in Participants With Moderately Impaired Hepatic Function Compared
Hepatic Impairment
Phase 12007-07-26
CompletedStudy of GA-GCB Enzyme Replacement Therapy in Type 1 Gaucher Disease Patients Previously Treated With Imigluce
Gaucher Disease
Phase 2 / Phase 32007-07-25
CompletedMaribavir Versus Oral Ganciclovir For The Prevention of Cytomegalovirus (CMV) Disease in Liver Transplant Reci
Cytomegalovirus Infections
Phase 32007-07-23
CompletedDose-Optimization Study Evaluating the Efficacy, Safety and Tolerability of Vyvanse (Lisdexamfetamine Dimesyla
Attention Deficit Hyperactivity Disorder (ADHD)
Phase 42007-06-28
CompletedA Classroom Study to Assess the Time of Onset of Vyvanse (Lisdexamfetamine Dimesylate) in Pediatric Subjects A
ADHD
Phase 32007-06-13
TerminatedDynepo Long-Term Safety Study
Anemia, Kidney Failure, Chronic
Phase 42007-06-06
TerminatedConversion From Standard Phosphate Binder Therapy to Fosrenol® (Lanthanum Carbonate) in Chronic Kidney Disease
Kidney Diseases
Phase 42007-05-22
CompletedStrategies in Maintenance for Patients Receiving Long-term Therapy (S.I.M.P.L.E.) With MMX (Multi-Matrix Syste
Ulcerative Colitis
Phase 42007-05-01
WithdrawnA Study of SPD465 in Young Adult Drivers With Attention-Deficit Hyperactivity Disorder (ADHD) Using Driving Si
Attention Deficit Hyperactivity Disorder
Phase 32007-04-30
CompletedSafety and Efficacy Study of Repeated Doses of DX-88 (Ecallantide) to Treat Attacks of Hereditary Angioedema (
Hereditary Angioedema (HAE)
Phase 32007-04-01
CompletedEfficacy Study of DX-88 (Ecallantide) to Treat Acute Attacks of Hereditary Angioedema (HAE)
Hereditary Angioedema (HAE)
Phase 32007-04-01
CompletedLong-term Effect of Lanthanum Carbonate on Bone
Hyperphosphatemia
2007-03-15
CompletedA Study of Gene-Activated® Human Glucocerebrosidase (GA-GCB) Enzyme Replacement Therapy in Gaucher Disease
Gaucher Disease, Type 1
Phase 32007-02-15
CompletedEvaluation of Safety and Activity of Celaderm in Healing Venous Leg Ulcers
Leg Ulcer, Varicose Ulcer
Phase 1 / Phase 22007-01-31
CompletedLong-term Metazym Treatment of Patients With Late Infantile Metachromatic Leukodystrophy (MLD)
Late Infantile Metachromatic Leukodystrophy
Phase 1 / Phase 22007-01-22
CompletedMetazym for the Treatment of Patients With Late Infantile Metachromatic Leukodystrophy (MLD)
Metachromatic Leukodystrophy (MLD)
Phase 12007-01-22
CompletedHead to Head Study Against Sevelamer Hydrochloride
Chronic Kidney Disease, Stage 5
Phase 32007-01-05
CompletedProphylactic Use of Maribavir for the Prevention of Cytomegalovirus (CMV) Disease in Stem Cell Transplant Reci
Cytomegalovirus Infections
Phase 32006-12-13
CompletedSPD503 (Guanfacine Hydrochloride) in ADHD Plus Oppositional Symptoms
ADHD
Phase 32006-12-04
CompletedThe Pharmacokinetics of Anagrelide in Elderly and Young Patients With Essential Thrombocythaemia (ET)
Essential Thrombocythaemia
Phase 22006-11-13
TerminatedDynepo Infrequent Dosing Study
Anemia, Kidney Failure
Phase 32006-10-30
CompletedPharmacokinetics of C1 Esterase Inhibitor in Hereditary Angioedema Subjects
Hereditary Angioedema
Phase 12006-10-09
CompletedOpen-Label C1 Esterase Inhibitor (C1INH-nf) for the Treatment of Acute Hereditary Angioedema (HAE) Attacks
Hereditary Angioedema
Phase 32006-09-21
CompletedA Double-Blind Multi-Dose Tolerability and Pharmacokinetic Study of Teduglutide
Pharmacokinetics and Safety of Elevated Doses
Phase 12006-09-06
CompletedOpen-Label C1 Esterase Inhibitor (C1INH-nf) for the Prevention of Acute Hereditary Angioedema (HAE) Attacks
Hereditary Angioedema
Phase 32006-06-27
CompletedLong Term Treatment of End Stage Renal Disease Patients With Lanthanum Carbonate (Fosrenol)
Hyperphosphatemia
2006-04-25
CompletedA Study of Anagrelide and Hydroxyurea in High-Risk Essential Thrombocythemia Patients
Thrombocythemia, Hemorrhagic
Phase 42006-01-13
CompletedEfficacy and Safety of Lanthanum Carbonate in Reducing Serum Phosphorus Levels in Subjects With Stage 3 and 4
Kidney Diseases
Phase 22006-01-11
CompletedEfficacy and Safety Study of DX-88 to Treat Acute Attacks of Hereditary Angioedema (HAE)
Hereditary Angioedema (HAE)
Phase 32005-12-31
CompletedHunter Outcome Survey (HOS)
Hunter Syndrome
2005-10-03
CompletedSafety and Efficacy of SPD465 in Adults With ADHD
Attention Deficit Disorder With Hyperactivity
Phase 22005-09-29
CompletedSafety and Pregnancy Outcomes in Thrombocythemia Patients Exposed to XAGRID® (Anagrelide Hydrochloride) Compar
Thrombocythemia, Essential
2005-05-31
CompletedSafety, Tolerability and Efficacy of SPD503 in Treating ADHD in Children Aged 6-17
Attention Deficit Disorder With Hyperactivity
Phase 22005-05-12
CompletedEfficacy and Safety of SPD465 in Adults With Moderately Symptomatic ADHD.
Attention Deficit Disorder With Hyperactivity
Phase 32005-04-25
CompletedEfficacy and Safety of SPD476 in Maintaining Remission in Patients With Ulcerative Colitis
Ulcerative Colitis
Phase 32005-04-08
CompletedC1 Esterase Inhibitor (C1INH-nf) for the Treatment of Acute Hereditary Angioedema (HAE) Attacks
Hereditary Angioedema
Phase 32005-03-14
CompletedC1 Esterase Inhibitor (C1INH-nf) for the Prevention of Acute Hereditary Angioedema (HAE) Attacks
Hereditary Angioedema
Phase 32005-03-14
CompletedSafety of SPD465 in Treating Adults With ADHD.
Attention Deficit Disorder With Hyperactivity
Phase 32005-03-10
CompletedSubcutaneous Treatment With Icatibant for Acute Attacks of Hereditary Angioedema (HAE)
Hereditary Angioedema
Phase 32005-03-01
CompletedEfficacy and Safety of SPD465 in Adults With ADHD
Attention Deficit Disorder With Hyperactivity
Phase 32005-01-27
CompletedEfficacy and Safety of Fosrenol in Treating Elevated Serum Phosphate Levels in Adults With End Stage Renal Dis
Kidney Failure, Chronic
Phase 42005-01-10
CompletedSafety and Efficacy Study of Teduglutide in Subjects With Short Bowel Syndrome Who Completed Protocol CL0600-0
Short Bowel Syndrome
Phase 32005-01-10
CompletedOpen Label Extension
Osteoporosis
Phase 32005-01-10
CompletedEfficacy and Safety of Lanthanum Carbonate and Sevelamer Hydrochloride in Patients Receiving Haemodialysis for
Kidney Failure, Chronic
Phase 32005-01-07
CompletedSubcutaneous Treatment With Icatibant for Acute Attacks of Hereditary Angioedema
Angioedema
Phase 32004-12-28
CompletedMaribavir for Prevention of CMV After Stem Cell Transplants
Cytomegalovirus Infection
Phase 22004-10-28
CompletedExtension of Study TKT024 Evaluating Long-Term Safety and Clinical Outcomes in MPS II Patients Receiving Idurs
Hunter Syndrome, Mucopolysaccharidosis II (MPS II)
Phase 2 / Phase 32004-09-13
CompletedOpen-Label Extension Study Evaluating Long Term Safety in Patients With Type 1 Gaucher Disease Receiving DRX00
Gaucher Disease
Phase 1 / Phase 22004-09-13
CompletedStudy to Assess the Benefit of Midodrine in the Treatment of Patients With Neurogenic Orthostatic Hypotension
Hypotension, Orthostatic
Phase 42004-09-08
CompletedSafety and Tolerability of SPD503 and Psychostimulants in Children and Adolescents Aged 6-17 With Attention-De
Attention Deficit Disorder With Hyperactivity
Phase 22004-08-16
CompletedThe Safety and Efficacy of SPD465 in Adults With Attention Deficit Hyperactivity Disorder (ADHD)
Attention-Deficit/Hyperactivity Disorder
Phase 22004-06-14
CompletedReplagal Enzyme Replacement Therapy for Children With Fabry Disease
Fabry Disease
Phase 22004-06-10
CompletedSafety and Efficacy Study of Teduglutide in Subjects With Short Bowel Syndrome
Short Bowel Syndrome
Phase 32004-05-25
CompletedEfficacy and Tolerability of Treatment With Lanthanum Carbonate in Patients With End Stage Renal Disease Recei
Kidney Failure, Chronic
Phase 32004-05-11
CompletedSafety and Efficacy of SPD503 in Treating ADHD in Children and Adolescents Aged 6-17
Attention Deficit Disorder With Hyperactivity
Phase 32004-03-30
CompletedSafety and Efficacy of ALX-0600 in Subjects With Active Crohn's Disease Who Completed Protocol CL0600-008
Crohn's Disease
Phase 22004-03-01
CompletedADDERALL XR (Mixed Salts of a Single-entity Amphetamine) and STRATTERA ( Atomoxetine Hydrochloride) Compared t
Attention Deficit Disorder With Hyperactivity
Phase 32004-02-25
CompletedEfficacy and Safety of Lanthanum in Controlling Serum Phosphate Levels in Subjects With End Stage Renal Diseas
Kidney Failure, Chronic
Phase 32004-02-09
CompletedCalcium Supplementation in Postmenopausal Women
Osteoporosis
Phase 32004-01-10
CompletedSafety and Efficacy of NPS 1776 in the Acute Treatment of Migraine Headaches
Migraine Headache
Phase 22003-12-31
CompletedEfficacy and Safety of Two Doses of SPD476 (Mesalazine) 2.4g and 4.8g Once Daily, With Reference to Asacol 0.8
Ulcerative Colitis
Phase 32003-12-04
CompletedSafety and Tolerability of SPD476 in Maintaining Remission in Patients With Ulcerative Colitis.
Colitis, Ulcerative
Phase 32003-11-26
CompletedSafety and Efficacy of ALX-0600 in Subjects With Active Crohn's Disease
Crohn's Disease
Phase 22003-11-12
CompletedEDEMA2: Evaluation of DX-88's Effect in Mitigating Angioedema
Hereditary Angioedema (HAE)
Phase 22003-11-01
CompletedSafety and Efficacy of SPD476 (Mesalazine) Given Twice Daily (2.4 g/Day) vs SPD476 Given as a Single Dose (4.8
Colitis, Ulcerative
Phase 32003-09-30
CompletedIduronate-2-sulfatase Enzyme Replacement Therapy in Mucopolysaccharidosis II (MPS II)
Mucopolysaccharidosis II
Phase 2 / Phase 32003-09-18
CompletedAnalog Classroom Study Comparison of ADDERALL XR With STRATTERA in Children Aged 6-12 With ADHD
ADHD
Phase 42003-08-05
CompletedSafety and Efficacy of ADDERALL XR in the Treatment of Adolescents Aged 13-17 With Attention Deficit Hyperacti
ADHD
Phase 32003-05-28
CompletedPhase II Dose-Ranging Study in Subjects With Mild to Moderate Ulcerative Colitis Treated With SPD476
Colitis, Ulcerative
Phase 22003-02-10
CompletedSafety and Efficacy of SPD503 in Treating Attention-Deficit/Hyperactivity Disorder (ADHD) in Children Aged 6-1
Attention Deficit Disorder With Hyperactivity
Phase 32003-01-29
CompletedA Long Term Study of Lanthanum Carbonate in Patients Requiring Dialysis Who Have Ived Lanthanum Carbonate in P
Kidney Failure, Chronic
Phase 32002-10-14
TerminatedA Phase IV Study in Subjects With Neurogenic Orthostatic Hypotension
Hypotension, Orthostatic
Phase 42002-09-05
CompletedOpen Label Extension Study of PREOS
Osteoporosis
Phase 32001-10-16
CompletedFabry Outcome Survey (FOS)
Fabry Disease
2001-04-01
CompletedTroxacitabine in Treating Patients With Chronic Myelogenous Leukemia
Leukemia
Phase 22000-12-11
CompletedTOP: Recombinant Human Parathyroid Hormone (ALX1-11) on Fracture Incidence in Women With Postmenopausal Osteop
Osteoporosis
Phase 32000-04-27
CompletedA Study for Patients With Neurogenic Orthostatic Hypotension
Hypotension, Orthostatic
Phase 41997-12-01
CompletedA Study to Assess the Safety and Efficacy of 3 Doses of ALX1-11 (50, 75, and 100µg) in the Treatment of Postme
Osteoporosis
Phase 21995-05-18
No Longer AvailableExpanded Access for the Prevention of Acute Attacks of 1) Hereditary Angioedema (HAE) in Children and 2) Non-h
Hereditary Angioedema (HAE), Angioedema
Approved For MarketingTreatment Protocol of Velaglucerase Alfa for Patients With Type 1 Gaucher Disease
Gaucher Disease, Type 1
No Longer AvailableTreatment Protocol of Replagal for Patients With Fabry Disease
Fabry Disease