Trials / Completed
CompletedNCT00555880
Study to Assess the Benefit of Midodrine in the Treatment of Patients With Neurogenic Orthostatic Hypotension
A Multi-Center, Double-Blind, Randomized, Placebo-controlled, Crossover Study to Assess the Clinical Benefit of Midodrine Hydrochloride in Subjects With Moderate to Severe Neurogenic Orthostatic Hypotension
- Status
- Completed
- Phase
- Phase 4
- Study type
- Interventional
- Enrollment
- 24 (actual)
- Sponsor
- Shire · Industry
- Sex
- All
- Age
- 19 Years
- Healthy volunteers
- Not accepted
Summary
The purpose of this clinical study is to evaluate the clinical effect of midodrine hydrochloride (ProAmatine®) compared to placebo in patients with orthostatic hypotension by measuring the time to onset of near syncopal symptoms and assessing several cardiovascular measurements, such as heart rate, blood pressure, and ECG, using the tilt table test.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Midodrine hydrochloride | one dose, 10-30mg, given orally |
| DRUG | Placebo | Placebo |
Timeline
- Start date
- 2004-09-08
- Primary completion
- 2005-03-21
- Completion
- 2005-03-21
- First posted
- 2007-11-09
- Last updated
- 2021-06-14
- Results posted
- 2015-05-21
Locations
11 sites across 1 country: United States
Source: ClinicalTrials.gov record NCT00555880. Inclusion in this directory is not an endorsement.