Clinical Trials Directory

Trials / Completed

CompletedNCT00734578

Efficacy and Safety of SPD503 in Combination With Psychostimulants

A Phase III, Double-Blind, Randomized, Placebo-Controlled, Multi-Center, Dose Optimization Study Evaluating the Efficacy and Safety of SPD503 in Combination With Psychostimulants in Children and Adolescents Aged 6-17 Years With a Diagnosis of Attention-Deficit/Hyperactivity Disorder (ADHD)

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
461 (actual)
Sponsor
Shire · Industry
Sex
All
Age
6 Years – 17 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to assess the efficacy and safety of SPD503 in subjects with ADHD when co-administered with psychostimulants in children and adolescents aged 6-17 years with a diagnosis of ADHD with a sub-optimal, partial response to stimulants.

Conditions

Interventions

TypeNameDescription
DRUGSPD503-AMSPD503 (Guanfacine Extended Release)-AM Optimized 1-4mg
DRUGSPD503-PMSPD503 (Guanfacine Extended Release)-PM Optimized 1-4mg
DRUGPlaceboPlacebo matched to Guanfacine Hydrochloride Extended Release

Timeline

Start date
2008-09-02
Primary completion
2009-12-10
Completion
2009-12-10
First posted
2008-08-14
Last updated
2021-06-14
Results posted
2010-11-23

Locations

61 sites across 1 country: United States

Source: ClinicalTrials.gov record NCT00734578. Inclusion in this directory is not an endorsement.

Efficacy and Safety of SPD503 in Combination With Psychostimulants (NCT00734578) · Clinical Trials Directory