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Trials / Completed

CompletedNCT03918239

A Study to Determine the Bioavailability of Lanadelumab (SHP643) Administered Subcutaneously With the Prefilled Syringe and the Autoinjector in Healthy Adult Volunteer Participants.

A Randomized, Open-label, Single-dose, Parallel-arm, Single-center, Phase 1 Study to Determine the Bioavailability of Lanadelumab Administered Subcutaneously With the Prefilled Syringe and the Autoinjector in Healthy Adult Volunteer Subjects

Status
Completed
Phase
Phase 1
Study type
Interventional
Enrollment
190 (actual)
Sponsor
Shire · Industry
Sex
All
Age
18 Years – 55 Years
Healthy volunteers
Accepted

Summary

The purpose of this study is to evaluate bioavailability of lanadelumab (SHP643) following a single, 2 milliliter (mL) subcutaneous (SC) dose of 300 milligrams (mg) delivered by prefilled syringe (PFS) or auto injector (AI) in healthy adult participants.

Conditions

Interventions

TypeNameDescription
DRUGSHP643Participants will receive injection of SHP643.

Timeline

Start date
2019-05-14
Primary completion
2019-11-13
Completion
2019-11-13
First posted
2019-04-17
Last updated
2020-12-08
Results posted
2020-12-08

Locations

1 site across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT03918239. Inclusion in this directory is not an endorsement.

A Study to Determine the Bioavailability of Lanadelumab (SHP643) Administered Subcutaneously With the Prefilled Syringe (NCT03918239) · Clinical Trials Directory