Trials / Completed
CompletedNCT01449240
Collection and Study of Cerebrospinal Fluid in Patients With Hunter Syndrome
A Cerebrospinal Fluid Collection Study in Pediatric and Adult Patients With Hunter Syndrome
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 10 (actual)
- Sponsor
- Shire · Industry
- Sex
- Male
- Age
- 70 Years
- Healthy volunteers
- Not accepted
Summary
The purpose of the study is to collect data on CSF biomarkers in patients with Hunter Syndrome that would serve as reference data for comparison with cognitively impaired patients with Hunter syndrome, patients with other lysosomal storage diseases, or other diseases with CNS involvement.
Detailed description
To determine levels of glycosaminoglycans (GAGs), including dermatan sulfate (DS) and heparan sulfate (HS), GAG-degradation products, and other biomarkers of central nervous system (CNS) and lysosomal function in cerebrospinal fluid (CSF) in pediatric and adult patients with Hunter syndrome.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | No treatment |
Timeline
- Start date
- 2012-11-12
- Primary completion
- 2013-12-20
- Completion
- 2013-12-20
- First posted
- 2011-10-10
- Last updated
- 2021-06-09
- Results posted
- 2014-12-05
Locations
7 sites across 2 countries: United States, United Kingdom
Source: ClinicalTrials.gov record NCT01449240. Inclusion in this directory is not an endorsement.