NCT01117051

Prucalopride Effects on Subjects With Chronic Non-cancer Pain Suffering From Opioid Induced Constipation

A 12-week, Randomised, Double-blind, Placebo-controlled Trial to Evaluate the Efficacy and Safety of Prucalopride in Subjects With Chronic Non-cancer Pain Suffering From Opioid Induced Constipation

• Status: Terminated
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 174 (actual)
• Sponsor: Shire · Industry
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The study will evaluate the efficacy, safety and tolerability of prucalopride over 12 weeks of treatment in subjects aged 18 years and older with chronic non-cancer pain, suffering from opioid induced constipation.

Conditions

• Non-cancer Pain
• Opioid Induced Constipation

Interventions

Type	Name	Description
DRUG	placebo	placebo
DRUG	prucalopride	1 or 2 mg prucalopride once daily before breakfast

Timeline

• Start date: 2010-05-19
• Primary completion: 2012-08-13
• Completion: 2012-08-13
• First posted: 2010-05-05
• Last updated: 2021-06-11
• Results posted: 2013-06-26

Locations

1 site across 1 country: Belgium