Trials / Completed
CompletedNCT01707667
Study to Investigate Prucalopride vs. Polyethylene Glycol 3350 on Colon Activity
An Open-label, Randomized, Crossover, Reader-blinded Study to Investigate the Effect of Prucalopride and Polyethylene Glycol 3350 on Colon Motility With Intramural Manometry in Subjects With Chronic Constipation
- Status
- Completed
- Phase
- Phase 4
- Study type
- Interventional
- Enrollment
- 13 (actual)
- Sponsor
- Shire · Industry
- Sex
- All
- Age
- 18 Years – 75 Years
- Healthy volunteers
- Not accepted
Summary
To evaluate the different effects of prucalopride and PEG 3350 + electrolytes on colon motor activity in subjects that are chronically constipated.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | prucalopride | One 2 mg tablet orally administered on Day 1 |
| DRUG | PEG 3350 | 13.8g polyethylene glycol (PEG) 3350 with sodium bicarbonate, sodium chloride, and potassium chloride as a solution in water. Administered twice orally on Day 1(once in the morning and once prior to lunch). |
Timeline
- Start date
- 2013-02-27
- Primary completion
- 2013-11-27
- Completion
- 2013-11-27
- First posted
- 2012-10-16
- Last updated
- 2021-07-02
- Results posted
- 2014-10-22
Locations
3 sites across 3 countries: United States, Belgium, United Kingdom
Source: ClinicalTrials.gov record NCT01707667. Inclusion in this directory is not an endorsement.