| Not Yet Recruiting | Outcome Research in Bowel Irrigation Techniques for the Treatment of Chronic Constipation and/or Faecal Incont NCT07473622 | Qufora A/S | N/A |
| Not Yet Recruiting | "Efficacy and Safety of Linaclotide in Chronic Constipation" NCT07431957 | Md Mehedi Shahriar | Phase 4 |
| Not Yet Recruiting | The Efficacy and Safety of Microbiota Transplantation Combined With Prebiotics for Treatment of Functional Con NCT07386795 | Peking Union Medical College Hospital | N/A |
| Recruiting | The Safety and Efficacy of Fecal Microbiota Transplantation Combined With Nutritional Intervention in the Trea NCT07387952 | Peking Union Medical College Hospital | N/A |
| Recruiting | MSOT and MRI for Non-invasive Assessment of Intestinal Transit Time in Children With Chronic Bowel Emptying Di NCT06911749 | Dr. med. Sonja Diez | N/A |
| Completed | Validation of New Type Radiopaque Marker in The Evaluation of Colonic Transit Time NCT06850415 | Mahidol University | N/A |
| Recruiting | Exploring the Potential Benefits of Probiotic Yogurt NCT06847919 | Wecare Probiotics Co., Ltd. | N/A |
| Completed | Comparing Manual and Automatic Colonic Massage for Chronic Constipation. NCT06695754 | usMIMA S.L. | — |
| Recruiting | Anorectal Manometery in Pediatric Chronic Refractory Constipation NCT06543979 | Ain Shams University | Phase 1 / Phase 2 |
| Not Yet Recruiting | Effect of Antibiotic Pretreatment on the Efficacy of WMT in the Treatment of Chronic Constipation NCT06427863 | Faming Zhang | N/A |
| Active Not Recruiting | "Which Type of Exercise is More Effective in Chronic Constipation? NCT06354855 | Necmettin Erbakan University | N/A |
| Terminated | Elobixibat for Chronic Constipation Without Defecation Desire NCT05703464 | International University of Health and Welfare | Phase 4 |
| Terminated | Effect of Transcutaneous Auricular Vagal Nerve Stimulation on Chronic Constipation NCT05723731 | Air Force Military Medical University, China | N/A |
| Completed | Drinking Effect of Electrolyzed Alkaline Reduced Water on Functional Constipation NCT05734859 | Wonju Severance Christian Hospital | N/A |
| Completed | The Combined Seed Extracts of Cassia Obtusifolia Linne and Foeniculum Vulgare Mill in Patients With Chronic Co NCT05548842 | Pusan National University Yangsan Hospital | N/A |
| Completed | Investigation of Spinal Posture and Anthropometric Characteristics of Women with Chronic Constipation NCT06621160 | Ondokuz Mayıs University | — |
| Unknown | Elobixibat for Chronic Constipation Without Defecation Desire NCT05165199 | Yokohama City University | Phase 4 |
| Unknown | Administration of a Natural Molecular Complex in Functional Chronic Constipation NCT05192317 | Aboca Spa Societa' Agricola | N/A |
| Unknown | The Efficacy of Massage and Reflexology Applications in Children With Cerebral Palsy NCT05202028 | Halic University | N/A |
| Completed | Effectiveness and Safety of Probiotic in Regulating Chronic Constipation NCT05980988 | Wecare Probiotics Co., Ltd. | N/A |
| Unknown | Long-term Elobixibat for Chronic Constipation NCT04784780 | Yokohama City University | Phase 4 |
| Recruiting | Sacral Neuromodulation as Treatment for Chronic Constipation NCT03819062 | McMaster University | N/A |
| Completed | Kiwifruit, Prunes, & Fiber for Abdominal and Bowel Symptoms in US Patients With Chronic Constipation NCT03569527 | University of Michigan | N/A |
| Completed | Synbiotic, Prebiotics and Probiotics in Children With Cerebral Palsy and Constipation NCT03117322 | Andrea Garcia Contreras | Phase 4 |
| Recruiting | Laparoscopic Ventral Mesh Rectopexy Combined With or Without Stapled Trans-anal Rectal Resection for Obstructe NCT03060330 | Renmin Hospital of Wuhan University | N/A |
| Unknown | Efficacy of Vibrating Capsule in Patients With Chronic Constipation NCT03508076 | Changhai Hospital | N/A |
| Completed | General Clinical Study of AJG555 in Pediatric Patients With Chronic Constipation NCT02961556 | EA Pharma Co., Ltd. | Phase 3 |
| Completed | A Study of Oral Dosing of ASP0456 in Patients With Chronic Constipation NCT02809105 | Astellas Pharma Inc | Phase 3 |
| Active Not Recruiting | Efficacy of Linaclotide in Type II Diabetics With Chronic Constipation NCT03119584 | Texas Tech University Health Sciences Center, El Paso | Phase 4 |
| Unknown | Effect of Mosapride on Gut Transit in Patients With Chronic Constipation or Constipated Irritable Bowel Syndro NCT02433847 | Seoul National University Hospital | Phase 4 |
| Completed | A Study to Evaluate Dose Responses of Efficacy and Safety of ASP0456 in Patient With Chronic Constipation NCT02425722 | Astellas Pharma Inc | Phase 2 |
| Completed | Phase II Study of KWA-0711 in Patients With Chronic Constipation (CC) NCT02343978 | Kissei Pharmaceutical Co., Ltd. | Phase 2 |
| Completed | Phase II Dose-Finding Study of KWA-0711 in Patients With Chronic Constipation (CC) NCT02281630 | Kissei Pharmaceutical Co., Ltd. | Phase 2 |
| Completed | Study to Evaluate the Effects of RM-131 in Patients With Chronic Constipation NCT02137642 | Motus Therapeutics, Inc. | Phase 1 |
| Completed | Effect to Linaclotide on Colonic Motility NCT06989268 | Universitaire Ziekenhuizen KU Leuven | Phase 4 |
| Completed | Perineal Self-Acupressure NCT01867944 | University of California, Los Angeles | N/A |
| Completed | Study to Investigate Prucalopride vs. Polyethylene Glycol 3350 on Colon Activity NCT01707667 | Shire | Phase 4 |
| Withdrawn | A Post Marketing Surveillance Study on the Safety and Effectiveness of Prucalopride in the Treatment of Chroni NCT01692132 | Janssen Pharmaceutica | — |
| Completed | Effect of PEG, Bisacodyl and Prucalopride on Colonic Motility in Healthy Subjects NCT03279341 | University Hospital, Gasthuisberg | Phase 4 |
| Completed | Effect of Propofol on Internal Anal Sphincter Pressure During ARM NCT01793753 | Massachusetts General Hospital | — |
| Completed | Connective Tissue Manipulation Improves Symptoms and Quality of Life in Patients With Chronic Constipation NCT02321124 | Hacettepe University | N/A |
| Completed | Safety and Efficacy of Linaclotide in Patients With Chronic Constipation and Prominent Abdominal Bloating NCT01642914 | Forest Laboratories | Phase 3 |
| Unknown | Reflexology for Chronic Constipation NCT01599156 | Shaare Zedek Medical Center | Phase 2 |
| Completed | A Phase 2 Study to Evaluate Pharmacodynamics of YKP10811 in Patients With Chronic or Functional Constipation NCT01523184 | SK Life Science, Inc. | Phase 2 |
| Completed | Study of Elobixibat (A3309) in Patients With Chronic Idiopathic Constipation NCT01007123 | Albireo | Phase 2 |
| Completed | Physiotherapeutic Intervention in Children With Chronic Functional Constipation NCT00906971 | Universidade Federal de Pernambuco | N/A |
| Completed | An Open-Label, Long-Term Safety Study of Linaclotide in Patients With Chronic Constipation or Irritable Bowel NCT00765999 | Forest Laboratories | Phase 3 |
| Completed | Acupuncture for Chronic Constipation NCT00746200 | National Taiwan University Hospital | Phase 3 |
| Completed | An Open-label, Long-term Safety Study of Linaclotide in Patients With Chronic Constipation or Irritable Bowel NCT00730171 | Ironwood Pharmaceuticals, Inc. | Phase 3 |
| Completed | Phase III, Randomized, Double-Blind, Placebo-Controlled, Trial of Linaclotide Administered to Patients With Ch NCT00765882 | Forest Laboratories | Phase 3 |
| Completed | Trial of Linaclotide in Patients With Chronic Constipation NCT00730015 | Ironwood Pharmaceuticals, Inc. | Phase 3 |
| Completed | Comparison of TCM and Laxatives for Adults With Chronic Constipation NCT00745147 | National Taiwan University Hospital | Phase 3 |
| Unknown | Clinical Efficacy and Safety Evaluation of the Drug Imescard Compound Water Smartweed Pills NCT00861562 | Hospital de Clinicas de Porto Alegre | Phase 3 |
| Completed | Effects of Oral PEG 3350 on Electrolyte Balance NCT00868985 | Norgine | Phase 1 |
| Unknown | Endoscopic Mucosal Resection (EMR) for Diagnosis of Hirschsprung's Disease NCT00671684 | Massachusetts General Hospital | Phase 1 / Phase 2 |
| Completed | Efficacy and Safety of TJ-100 in the Treatment of Chronic Constipation NCT00522093 | Showa Inan General Hospital | N/A |
| Terminated | Phase II, Randomized, Placebo-Controlled Study of ATI-7505 in Patients With Chronic Idiopathic Constipation NCT00501241 | Procter and Gamble | Phase 2 |
| Completed | Dose-range-finding, Phase 2 Trial of Oral Linaclotide Acetate Administered to Patients With Chronic Constipati NCT00402337 | Ironwood Pharmaceuticals, Inc. | Phase 2 |
| Completed | Evaluate the Safety and Efficacy of a 5-HT4 Agonist in Chronic Constipation (ACCORD Trial) NCT00391820 | Alfasigma S.p.A. | Phase 2 |
| Completed | Effect of Chinese Herb on Chronic Constipation for Residents in Long-Term Care Units NCT00354575 | National Taiwan University Hospital | Phase 2 |
| Terminated | Effect of Tegaserod on Orocecal Transit in Elderly Chronic Constipation Patients NCT00348634 | Novartis | Phase 4 |
| Completed | Study of Stapled Transanal Rectal Resection (STARR) Surgery in Refractory Constipation Associated With Obstruc NCT00256984 | Ethicon Endo-Surgery | Phase 4 |
| Completed | To Determine the Effect of Forlax® Treatment in Children With Chronic Constipation Who May Also Suffer From So NCT00255372 | Ipsen | Phase 3 |
| Completed | Efficacy, Safety and Tolerability of Tegaserod in Patients With Chronic Constipation NCT00149877 | Novartis | Phase 4 |
| Completed | Assessment of Efficacy and Safety of Tegaserod in Male Patients With Chronic Constipation. NCT00141089 | Novartis | Phase 3 |
| Completed | Laxative Effectiveness of a Phytotherapeutic Tea NCT00872430 | Hospital de Clinicas de Porto Alegre | Phase 2 |
| Completed | Study to Examine the Efficacy and Safety of Movicol in the Treatment of Chronic Constipation in Children NCT00403819 | Norgine | Phase 3 |
| Completed | An Open Single Centre Study To Assess Treatment of Chronic Constipation in Children NCT00403897 | Norgine | Phase 3 |
| Completed | Movicol in Childhood Constipation (ProMotion Study) NCT00404040 | Norgine | Phase 2 |
| Completed | Study to Evaluate Long-Term Safety, Tolerability, and Satisfaction With Prucalopride in Chronic Constipation NCT00987844 | Movetis | Phase 3 |
| Completed | Study to Evaluate Long-Term Tolerability and Safety of Oral Prucalopride in Chronic Constipation NCT01070615 | Movetis | Phase 3 |
| Completed | Effect of Prucalopride in Patients With Severe Chronic Idiopathic Constipation NCT00576511 | Movetis | Phase 2 |
| Completed | A Single-blind, Dose-tapering Study of KWA-0711 in Patients With Chronic Constipation NCT01937663 | Kissei Pharmaceutical Co., Ltd. | Phase 2 |
| Completed | A Single-blind, Dose-titration Study of KWA-0711 in Patients With Chronic Constipation NCT01938196 | Kissei Pharmaceutical Co., Ltd. | Phase 2 |